Multifidus muscle changes after back injury are characterized by structural remodeling of muscle, adipose and connective tissue, but not muscle atrophy: molecular and … PW Hodges, G James, L Blomster, L Hall, A Schmid, C Shu, C Little, ... Spine 40 (14), 1057-1071, 2015 | 137 | 2015 |
The cartilage extracellular matrix as a transient developmental scaffold for growth plate maturation J Melrose, C Shu, JM Whitelock, MS Lord Matrix Biology 52, 363-383, 2016 | 86 | 2016 |
Mechanical destabilization induced by controlled annular incision of the intervertebral disc dysregulates metalloproteinase expression and induces disc degeneration J Melrose, C Shu, C Young, R Ho, MM Smith, AA Young, SS Smith, ... Spine 37 (1), 18-25, 2012 | 78 | 2012 |
Can proinflammatory cytokine gene expression explain multifidus muscle fiber changes after an intervertebral disc lesion? PW Hodges, G James, L Blomster, L Hall, AB Schmid, C Shu, C Little, ... Spine 39 (13), 1010-1017, 2014 | 73 | 2014 |
Comparative immunolocalisation of perlecan with collagen II and aggrecan in human foetal, newborn and adult ovine joint tissues demonstrates perlecan as an early developmental … SM Smith, C Shu, J Melrose Histochemistry and cell biology 134, 251-263, 2010 | 66 | 2010 |
Macrophage polarization contributes to local inflammation and structural change in the multifidus muscle after intervertebral disc injury G James, KA Sluka, L Blomster, L Hall, AB Schmid, CC Shu, CB Little, ... European Spine Journal 27, 1744-1756, 2018 | 60 | 2018 |
Ablation of perlecan domain 1 heparan sulfate reduces progressive cartilage degradation, synovitis, and osteophyte size in a preclinical model of posttraumatic osteoarthritis CC Shu, MT Jackson, MM Smith, SM Smith, S Penm, MS Lord, ... Arthritis & Rheumatology 68 (4), 868-879, 2016 | 54 | 2016 |
Allogeneic mesenchymal precursor cells promote healing in postero-lateral annular lesions and improve indices of lumbar intervertebral disc degeneration in an ovine model BJC Freeman, JS Kuliwaba, CF Jones, CC Shu, CJ Colloca, ... Spine 41 (17), 1331-1339, 2016 | 47 | 2016 |
A histopathological scheme for the quantitative scoring of intervertebral disc degeneration and the therapeutic utility of adult mesenchymal stem cells for intervertebral disc … CC Shu, MM Smith, SM Smith, AJ Dart, CB Little, J Melrose International journal of molecular sciences 18 (5), 1049, 2017 | 39 | 2017 |
Use of FGF-2 and FGF-18 to direct bone marrow stromal stem cells to chondrogenic and osteogenic lineages C Shu, SM Smith, CB Little, J Melrose Future science OA 2 (4), FSO142, 2016 | 38 | 2016 |
Pericellular colocalisation and interactive properties of type VI collagen and perlecan in the intervertebral disc AJ Hayes, CC Shu, MS Lord, CB Little, JM Whitelock, J Melrose European Cells and Materials 32, 40-57, 2016 | 36 | 2016 |
The relationship between synovial inflammation, structural pathology, and pain in post-traumatic osteoarthritis: differential effect of stem cell and hyaluronan treatment CC Shu, S Zaki, V Ravi, A Schiavinato, MM Smith, CB Little Arthritis Research & Therapy 22, 1-13, 2020 | 35 | 2020 |
Hyaluronan oligosaccharides stimulate matrix metalloproteinase and anabolic gene expression in vitro by intervertebral disc cells and annular repair in vivo ES Fuller, C Shu, MM Smith, CB Little, J Melrose Journal of tissue engineering and regenerative medicine 12 (1), e216-e226, 2018 | 34 | 2018 |
Catabolism of fibromodulin in developmental rudiment and pathologic articular cartilage demonstrates novel roles for MMP-13 and ADAMTS-4 in C-terminal processing of SLRPs CC Shu, CR Flannery, CB Little, J Melrose International Journal of Molecular Sciences 20 (3), 579, 2019 | 29 | 2019 |
Mesenchymal stem cell treatment of intervertebral disc lesion prevents fatty infiltration and fibrosis of the multifidus muscle, but not cytokine and muscle fiber changes G James, L Blomster, L Hall, AB Schmid, CC Shu, CB Little, J Melrose, ... Spine 41 (15), 1208-1217, 2016 | 26 | 2016 |
Efficacy of administered mesenchymal stem cells in the initiation and co‐ordination of repair processes by resident disc cells in an ovine (Ovis aries) large … CC Shu, A Dart, R Bell, C Dart, E Clarke, MM Smith, CB Little, J Melrose JOR spine 1 (4), e1037, 2018 | 24 | 2018 |
The ovine newborn and human foetal intervertebral disc contain perlecan and aggrecan variably substituted with native 7D4 CS sulphation motif: spatiotemporal immunolocalisation … C Shu, C Hughes, SM Smith, MM Smith, A Hayes, B Caterson, CB Little, ... Glycoconjugate journal 30, 717-725, 2013 | 24 | 2013 |
Comparative immunolocalisation of perlecan, heparan sulphate, fibroblast growth factor-18, and fibroblast growth factor receptor-3 and their prospective roles in chondrogenic … C Shu, SS Smith, CB Little, J Melrose European Spine Journal 22, 1774-1784, 2013 | 20 | 2013 |
Confocal microscopy demonstrates association of LTBP-2 in fibrillin-1 microfibrils and colocalisation with perlecan in the disc cell pericellular matrix AJ Hayes, MA Gibson, C Shu, J Melrose Tissue and Cell 46 (3), 185-197, 2014 | 19 | 2014 |
Flow cytometry analysis of immune cell subsets within the murine spleen, bone marrow, lymph nodes and synovial tissue in an osteoarthritis model P Haubruck, AC Colbath, Y Liu, S Stoner, C Shu, CB Little JoVE (Journal of Visualized Experiments), e61008, 2020 | 15 | 2020 |