| Neurokinin 1 receptor signaling in endosomes mediates sustained nociception and is a viable therapeutic target for prolonged pain relief DD Jensen, TM Lieu, ML Halls, NA Veldhuis, WL Imlach, QN Mai, ... Science Translational Medicine 9 (392), eaal3447, 2017 | 191 | 2017 |
| Cathepsin S causes inflammatory pain via biased agonism of PAR2 and TRPV4 P Zhao, TM Lieu, N Barlow, M Metcalf, NA Veldhuis, DD Jensen, M Kocan, ... Journal of Biological Chemistry 289 (39), 27215-27234, 2014 | 182 | 2014 |
| G protein-coupled receptors: dynamic machines for signaling pain and itch P Geppetti, NA Veldhuis, TM Lieu, NW Bunnett Neuron 88 (4), 635-649, 2015 | 170 | 2015 |
| Protease-activated receptor 2 (PAR2) protein and transient receptor potential vanilloid 4 (TRPV4) protein coupling is required for sustained inflammatory signaling DP Poole, S Amadesi, NA Veldhuis, FC Abogadie, TM Lieu, W Darby, ... Journal of biological chemistry 288 (8), 5790-5802, 2013 | 165 | 2013 |
| The G protein–coupled receptor–transient receptor potential channel axis: molecular insights for targeting disorders of sensation and inflammation NA Veldhuis, DP Poole, M Grace, P McIntyre, NW Bunnett Pharmacological Reviews 67 (1), 36-73, 2015 | 164 | 2015 |
| Endosomal signaling of the receptor for calcitonin gene-related peptide mediates pain transmission RE Yarwood, WL Imlach, TM Lieu, NA Veldhuis, DD Jensen, ... Proceedings of the National Academy of Sciences 114 (46), 12309-12314, 2017 | 152 | 2017 |
| Protease-activated receptor-2 in endosomes signals persistent pain of irritable bowel syndrome NN Jimenez-Vargas, LA Pattison, P Zhao, TM Lieu, R Latorre, DD Jensen, ... Proceedings of the National Academy of Sciences 115 (31), E7438-E7447, 2018 | 149 | 2018 |
| Quantification and potential functions of endogenous agonists of transient receptor potential channels in patients with irritable bowel syndrome N Cenac, T Bautzova, P Le Faouder, NA Veldhuis, DP Poole, C Rolland, ... Gastroenterology 149 (2), 433-444. e7, 2015 | 130 | 2015 |
| Cysteine-rich secretory protein 4 is an inhibitor of transient receptor potential M8 with a role in establishing sperm function GM Gibbs, G Orta, T Reddy, AJ Koppers, P Martínez-López, ... Proceedings of the National Academy of Sciences 108 (17), 7034-7039, 2011 | 118 | 2011 |
| A pH-responsive nanoparticle targets the neurokinin 1 receptor in endosomes to prevent chronic pain PD Ramírez-García, JS Retamal, P Shenoy, W Imlach, M Sykes, N Truong, ... Nature Nanotechnology 14 (12), 1150-1159, 2019 | 113 | 2019 |
| The multi-layered regulation of copper translocating P-type ATPases NA Veldhuis, AP Gaeth, RB Pearson, K Gabriel, J Camakaris Biometals 22, 177-190, 2009 | 85 | 2009 |
| Endosomal signaling of delta opioid receptors is an endogenous mechanism and therapeutic target for relief from inflammatory pain NN Jimenez-Vargas, J Gong, MJ Wisdom, DD Jensen, R Latorre, ... Proceedings of the National Academy of Sciences 117 (26), 15281-15292, 2020 | 82 | 2020 |
| A novel ultra-stable, monomeric green fluorescent protein for direct volumetric imaging of whole organs using CLARITY DJ Scott, NJ Gunn, KJ Yong, VC Wimmer, NA Veldhuis, LM Challis, ... Scientific reports 8 (1), 667, 2018 | 76 | 2018 |
| Cellular interactions of liposomes and PISA nanoparticles during human blood flow in a microvascular network MN Vu, HG Kelly, AK Wheatley, S Peng, EH Pilkington, NA Veldhuis, ... Small 16 (33), 2002861, 2020 | 75 | 2020 |
| Schwann cell endosome CGRP signals elicit periorbital mechanical allodynia in mice F De Logu, R Nassini, A Hegron, L Landini, DD Jensen, R Latorre, J Ding, ... Nature communications 13 (1), 646, 2022 | 72 | 2022 |
| Phosphorylation regulates copper-responsive trafficking of the Menkes copper transporting P-type ATPase NA Veldhuis, VA Valova, AP Gaeth, N Palstra, KM Hannan, BJ Michell, ... The international journal of biochemistry & cell biology 41 (12), 2403-2412, 2009 | 69 | 2009 |
| N-glycosylation determines ionic permeability and desensitization of the TRPV1 capsaicin receptor NA Veldhuis, MJ Lew, FC Abogadie, DP Poole, EA Jennings, JJ Ivanusic, ... Journal of Biological Chemistry 287 (26), 21765-21772, 2012 | 61 | 2012 |
| Activation of mu opioid receptors sensitizes transient receptor potential vanilloid type 1 (TRPV1) via β-arrestin-2-mediated cross-talk MP Rowan, SM Bierbower, MA Eskander, K Szteyn, ED Por, R Gomez, ... PloS one 9 (4), e93688, 2014 | 55 | 2014 |
| The tyrosine kinase inhibitor bafetinib inhibits PAR2‐induced activation of TRPV4 channels in vitro and pain in vivo MS Grace, T Lieu, B Darby, FC Abogadie, N Veldhuis, NW Bunnett, ... British journal of pharmacology 171 (16), 3881-3894, 2014 | 54 | 2014 |
| Selective G protein signaling driven by substance P–neurokinin receptor dynamics JA Harris, B Faust, AB Gondin, MA Dämgen, CM Suomivuori, NA Veldhuis, ... Nature chemical biology 18 (1), 109-115, 2022 | 49 | 2022 |
Daniel PooleMonash Institute of Pharmaceutical Sciences, Monash UniversityVerified email at Monash.edu
