Lysine-specific histone demethylase 1A regulates macrophage polarization and checkpoint molecules in the tumor microenvironment of triple-negative breast cancer AHY Tan, WJ Tu, R McCuaig, K Hardy, T Donovan, S Tsimbalyuk, ... Frontiers in Immunology 10, 447594, 2019 | 70 | 2019 |
Structural basis for importin alpha 3 specificity of W proteins in Hendra and Nipah viruses KM Smith, S Tsimbalyuk, MR Edwards, EM Cross, J Batra, ... Nature communications 9 (1), 3703, 2018 | 55 | 2018 |
Targeting nuclear LSD1 to reprogram cancer cells and reinvigorate exhausted T cells via a novel LSD1-EOMES switch WJ Tu, RD McCuaig, AHY Tan, K Hardy, N Seddiki, S Ali, JE Dahlstrom, ... Frontiers in Immunology 11, 1228, 2020 | 42 | 2020 |
Structural basis for importin-α binding of the human immunodeficiency virus tat KM Smith, Z Himiari, S Tsimbalyuk, JK Forwood Scientific reports 7 (1), 1650, 2017 | 29 | 2017 |
The intrinsically disordered W protein is multifunctional during Henipavirus infection, disrupting host signalling pathways and nuclear import S Tsimbalyuk, EM Cross, M Hoad, CM Donnelly, JA Roby, JK Forwood Cells 9 (8), 1913, 2020 | 17 | 2020 |
Henipavirus W proteins interact with 14-3-3 to modulate host gene expression MR Edwards, M Hoad, S Tsimbalyuk, AR Menicucci, I Messaoudi, ... Journal of Virology 94 (14), 10.1128/jvi. 00373-20, 2020 | 17 | 2020 |
MERS-CoV ORF4b employs an unusual binding mechanism to target IMPα and block innate immunity TS Munasinghe, MR Edwards, S Tsimbalyuk, OA Vogel, KM Smith, ... Nature Communications 13 (1), 1604, 2022 | 14 | 2022 |
Targeting novel LSD1-dependent ACE2 demethylation domains inhibits SARS-CoV-2 replication WJ Tu, RD McCuaig, M Melino, DJ Rawle, TT Le, K Yan, A Suhrbier, ... Cell Discovery 7 (1), 37, 2021 | 13 | 2021 |
In vivo inhibition of nuclear ACE2 translocation protects against SARS-CoV-2 replication and lung damage through epigenetic imprinting WJ Tu, M Melino, J Dunn, RD McCuaig, H Bielefeldt-Ohmann, ... Nature Communications 14 (1), 3680, 2023 | 7 | 2023 |
SpeG polyamine acetyltransferase enzyme from Bacillus thuringiensis forms a dodecameric structure and exhibits high catalytic efficiency S Tsimbalyuk, A Shornikov, ML Kuhn, JK Forwood Journal of structural biology 210 (3), 107506, 2020 | 6 | 2020 |
Selective Targeting of Protein Kinase C (PKC)-θ Nuclear Translocation Reduces Mesenchymal Gene Signatures and Reinvigorates Dysfunctional CD8+ T Cells in … J Dunn, RD McCuaig, AHY Tan, WJ Tu, F Wu, KM Wagstaff, A Zafar, S Ali, ... Cancers 14 (6), 1596, 2022 | 5 | 2022 |
Structural characterization of human importin alpha 7 in its cargo-free form at 2.5 Å resolution S Tsimbalyuk, CM Donnelly, JK Forwood Scientific Reports 12 (1), 315, 2022 | 3 | 2022 |
Structural and Kinetic Characterization of the SpeG Spermidine/Spermine N-acetyltransferase from Methicillin-Resistant Staphylococcus aureus USA300 S Tsimbalyuk, A Shornikov, P Srivastava, VTB Le, I Warren, ... Cells 12 (14), 1829, 2023 | 2 | 2023 |
Structural characterisation of a MAPR‐related archaeal cytochrome b5M protein S Teakel, M Marama, D Aragão, S Tsimbalyuk, ERR Mackie, ... FEBS letters 596 (18), 2409-2417, 2022 | 2 | 2022 |
The Vibrio cholerae SpeG Spermidine/Spermine N-Acetyltransferase Allosteric Loop and β6-β7 Structural Elements Are Critical for Kinetic Activity VTB Le, S Tsimbalyuk, EQ Lim, A Solis, D Gawat, P Boeck, EQ Lim, ... Frontiers in Molecular Biosciences 8, 645768, 2021 | 1 | 2021 |
Correction: Tsimbalyuk et al. The Intrinsically Disordered W Protein Is Multifunctional during Henipavirus Infection, Disrupting Host Signalling Pathways and Nuclear Import … S Tsimbalyuk, EM Cross, M Hoad, CM Donnelly, JA Roby, JK Forwood Cells 11 (8), 1290, 2022 | | 2022 |
The Intrinsically DisorderedW Protein Is Multifunctional during Henipavirus Infection, Disrupting Host Signalling Pathways and Nuclear Import (vol 9, 1913, 2020) S Tsimbalyuk, EM Cross, M Hoad, CM Donnelly, JA Roby, JK Forwood CELLS 11 (8), 2022 | | 2022 |
Understanding viral host interactions that modulate nuclear transport and innate immunity S Tsimbalyuk, KM Smith, MR Edwards, EM Cross, J Batra, ... Acta Crystallographica Section A: Foundations and Advances 77, C98-C98, 2021 | | 2021 |
Author Correction: Targeting novel LSD1-dependent ACE2 demethylation domains inhibits SARS-CoV-2 replication (Cell Discovery,(2021), 7, 1,(37), 10.1038/s41421-021-00279-w) WJ Tu, RD McCuaig, M Melino, DJ Rawle, TT Le, K Yan, A Suhrbier, ... Cell Discovery 7, 1-2, 2021 | | 2021 |
Proteins in health and disease: A structural approach to understanding cell mechanisms S Tsimbalyuk | | 2021 |