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Bjorn Bakker
Bjorn Bakker
Post-doctoral fellow at the Francis Crick Institute
Verified email at crick.ac.uk
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Cited by
Year
Centrosome amplification is sufficient to promote spontaneous tumorigenesis in mammals
MS Levine, B Bakker, B Boeckx, J Moyett, J Lu, B Vitre, DC Spierings, ...
Developmental cell 40 (3), 313-322. e5, 2017
3562017
Single-cell sequencing reveals karyotype heterogeneity in murine and human malignancies
B Bakker, A Taudt, ME Belderbos, D Porubsky, DCJ Spierings, ...
Genome biology 17, 1-15, 2016
2312016
Ongoing chromosomal instability and karyotype evolution in human colorectal cancer organoids
ACF Bolhaquerio, B Ponsioen, B Bakker, SJ Klaassen, E Kucukosse, ...
Nature Genetics 51, 824-834, 2019
1912019
Lung adenocarcinoma promotion by air pollutants
W Hill, EL Lim, CE Weeden, C Lee, M Augustine, K Chen, FC Kuan, ...
Nature 616 (7955), 159-167, 2023
1782023
Single-cell whole genome sequencing reveals no evidence for common aneuploidy in normal and Alzheimer’s disease neurons
H van den Bos, DCJ Spierings, A Taudt, B Bakker, D Porubský, ...
Genome biology 17 (1), 116, 2016
1572016
p53 prohibits propagation of chromosome segregation errors that produce structural aneuploidies
M Soto, JA Raaijmakers, B Bakker, DCJ Spierings, PM Lansdorp, F Foijer, ...
Cell reports 19 (12), 2423-2431, 2017
1542017
FoxM1 repression during human aging leads to mitotic decline and aneuploidy-driven full senescence
JC Macedo, S Vaz, B Bakker, R Rui, PL Bakker, JM Escandell, ...
Nature Communications 9, 2834, 2018
1132018
Non-random mis-segregation of human chromosomes
JT Worrall, N Tamura, A Mazzagatti, N Shaikh, T van Lingen, B Bakker, ...
Cell reports 23 (11), 3366-3380, 2018
1072018
DNA Replication Vulnerabilities Render Ovarian Cancer Cells Sensitive to Poly(ADP-Ribose) Glycohydrolase Inhibitors
N Pillay, A Tighe, L Nelson, S Littler, C Coulson-Gilmer, N Bah, A Golder, ...
Cancer Cell 35 (3), 518-533.E8, 2019
972019
Premature mitotic entry induced by ATR inhibition potentiates olaparib inhibition‐mediated genomic instability, inflammatory signaling and cytotoxicity in BRCA2‐deficient …
PM Schoonen, YP Kok, E Wierenga, B Bakker, F Foijer, DCJ Spierings, ...
Molecular Oncology, 2019
772019
How to count chromosomes in a cell: An overview of current and novel technologies
B Bakker, H van den Bos, PM Lansdorp, F Foijer
BioEssays 37 (5), 570-577, 2015
762015
Deletion of the MAD2L1 spindle assembly checkpoint gene is tolerated in mouse models of acute T-cell lymphoma and hepatocellular carcinoma
F Foijer, LA Albacker, B Bakker, DC Spierings, Y Yue, SZ Xie, S Davis, ...
Elife 6, e20873, 2017
742017
A living biobank of ovarian cancer ex vivo models reveals profound mitotic heterogeneity
L Nelson, A Tighe, A Golder, S Littler, B Bakker, D Moralli, ...
Nature communications 11 (1), 822, 2020
662020
Transient genomic instability drives tumorigenesis through accelerated clonal evolution
O Shoshani, B Bakker, L de Haan, AE Tijhuis, Y Wang, DH Kim, ...
Genes & development 35 (15-16), 1093-1108, 2021
552021
E2F-family members engage the PIDDosome to limit hepatocyte ploidy in liver development and regeneration
VC Sladky, K Knapp, C Soratroi, J Heppke, F Eichin, L Rocamora-Reverte, ...
Developmental cell 52 (3), 335-349. e7, 2020
532020
Nuclear chromosome locations dictate segregation error frequencies
SJ Klaasen, MA Truong, RH van Jaarsveld, I Koprivec, V Štimac, ...
Nature 607 (7919), 604-609, 2022
492022
CINcere Modelling: What Have Mouse Models for Chromosome Instability Taught Us?
JE Simon, B Bakker, F Foijer
Chromosomal Instability in Cancer Cells, 39-60, 2015
452015
Quantification of Aneuploidy in Mammalian Systems
H Van den Bos, B Bakker, A Taudt, V Guryev, M Colomé-Tatché, ...
Cellular Senescence, 159-190, 2018
442018
CITED2-mediated human hematopoietic stem cell maintenance is critical for acute myeloid leukemia
PM Korthuis, G Berger, B Bakker, M Rozenveld-Geugien, J Jaques, ...
Leukemia 29 (3), 625-635, 2015
442015
Extensive clonal branching shapes the evolutionary history of high-risk pediatric cancers
N Andersson, B Bakker, J Karlsson, A Valind, L Holmquist Mengelbier, ...
Cancer research 80 (7), 1512-1523, 2020
412020
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