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Kirsten McMahon
Kirsten McMahon
University of Queensland, The Francis Crick Institute
Verified email at uq.edu.au
Title
Cited by
Cited by
Year
A Genomic Safe Haven for Mutant Complementation in Cryptococcus neoformans
SDM Arras, JL Chitty, KL Blake, BL Schulz, JA Fraser
PloS one 10 (4), e0122916, 2015
872015
Disruption of de Novo Adenosine Triphosphate (ATP) Biosynthesis Abolishes Virulence in Cryptococcus neoformans
RD Blundell, SJ Williams, SDM Arras, JL Chitty, KL Blake, DJ Ericsson, ...
ACS infectious diseases 2 (9), 651-663, 2016
222016
Manipulation of a spider peptide toxin alters its affinity for lipid bilayers and potency and selectivity for voltage-gated sodium channel subtype 1.7
AJ Agwa, P Tran, A Mueller, HNT Tran, JR Deuis, MR Israel, KL McMahon, ...
Journal of Biological Chemistry 295 (15), 5067-5080, 2020
202020
Small cyclic sodium channel inhibitors
S Peigneur, C da Costa Oliveira, FC de Sousa Fonseca, KL McMahon, ...
Biochemical pharmacology 183, 114291, 2021
172021
Discovery, Pharmacological Characterisation and NMR Structure of the Novel µ-Conotoxin SxIIIC, a Potent and Irreversible NaV Channel Inhibitor
KL McMahon, HNT Tran, JR Deuis, RJ Lewis, I Vetter, CI Schroeder
Biomedicines 8 (10), 391, 2020
162020
Cryptococcus neoformans ADS lyase is an enzyme essential for virulence whose crystal structure reveals features exploitable in antifungal drug design
JL Chitty, KL Blake, RD Blundell, YQAE Koh, M Thompson, ...
Journal of Biological Chemistry 292 (28), 11829-11839, 2017
152017
Structural and functional insights into the inhibition of human voltage-gated sodium channels by μ-conotoxin KIIIA disulfide isomers
HNT Tran, KL McMahon, JR Deuis, I Vetter, CI Schroeder
Journal of Biological Chemistry 298 (3), 2022
92022
The Tarantula Venom Peptide Eo1a Binds to the Domain II S3-S4 Extracellular Loop of Voltage-Gated Sodium Channel NaV1.8 to Enhance Activation
JR Deuis, L Ragnarsson, SD Robinson, Z Dekan, L Chan, AH Jin, P Tran, ...
Frontiers in Pharmacology 12, 789570, 2022
72022
Pain-causing stinging nettle toxins target TMEM233 to modulate NaV1.7 function
S Jami, JR Deuis, T Klasfauseweh, X Cheng, S Kurdyukov, F Chung, ...
Nature Communications 14 (1), 2442, 2023
62023
Evaluation of efficient non-reducing enzymatic and chemical ligation strategies for complex disulfide-rich peptides
HNT Tran, P Tran, JR Deuis, KL McMahon, K Yap, DJ Craik, I Vetter, ...
Bioconjugate chemistry 32 (11), 2407-2419, 2021
62021
µ-Conotoxins Targeting the Human Voltage-Gated Sodium Channel Subtype NaV1.7
KL McMahon, HNT Tran, JR Deuis, DJ Craik, I Vetter, CI Schroeder
Toxins 14 (9), 600, 2022
42022
Pharmacological activity and NMR solution structure of the leech peptide HSTX-I
KL McMahon, B Tay, JR Deuis, BS Tanaka, S Peigneur, AH Jin, J Tytgat, ...
Biochemical pharmacology 181, 114082, 2020
42020
Identification of sodium channel toxins from marine cone snails of the subgenera Textilia and Afonsoconus
KL McMahon, H O’Brien, CI Schroeder, JR Deuis, D Venkatachalam, ...
Cellular and Molecular Life Sciences 80 (10), 287, 2023
12023
Voltage-Gated Sodium Channel Inhibition by µ-Conotoxins
KL McMahon, I Vetter, CI Schroeder
Toxins 16 (1), 55, 2024
2024
Changes in Potency and Subtype Selectivity of Bivalent NaV Toxins are Knot-Specific
P Tran, HNT Tran, KL McMahon, JR Deuis, L Ragnarsson, A Norman, ...
Bioconjugate Chemistry 34 (6), 1072-1083, 2023
2023
Solving painful problems: Developing potent and selective NaV channel inhibitors from animal venom
KL McMahon
2021
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Articles 1–16