Alan Aderem
Alan Aderem
Verified email at
Cited by
Cited by
The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5
F Hayashi, KD Smith, A Ozinsky, TR Hawn, CY Eugene, DR Goodlett, ...
Nature 410 (6832), 1099-1103, 2001
Toll-like receptors in the induction of the innate immune response
A Aderem, RJ Ulevitch
Nature 406 (6797), 782-787, 2000
Mechanisms of phagocytosis in macrophages
A Aderem, DM Underhill
Annual review of immunology 17 (1), 593-623, 1999
The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between toll-like receptors
A Ozinsky, DM Underhill, JD Fontenot, AM Hajjar, KD Smith, CB Wilson, ...
Proceedings of the National Academy of Sciences 97 (25), 13766-13771, 2000
The Toll-like receptor 2 is recruited to macrophage phagosomes and discriminates between pathogens
DM Underhill, A Ozinsky, AM Hajjar, A Stevens, CB Wilson, M Bassetti, ...
Nature 401 (6755), 811-815, 1999
Lipocalin 2 mediates an innate immune response to bacterial infection by sequestrating iron
TH Flo, KD Smith, S Sato, DJ Rodriguez, MA Holmes, RK Strong, S Akira, ...
Nature 432 (7019), 917-921, 2004
The evolution of vertebrate Toll-like receptors
JC Roach, G Glusman, L Rowen, A Kaur, MK Purcell, KD Smith, LE Hood, ...
Proceedings of the National Academy of Sciences 102 (27), 9577-9582, 2005
Cytoplasmic flagellin activates caspase-1 and secretion of interleukin 1β via Ipaf
EA Miao, CM Alpuche-Aranda, M Dors, AE Clark, MW Bader, SI Miller, ...
Nature immunology 7 (6), 569-575, 2006
Toll-like receptor-2 mediates mycobacteria-induced proinflammatory signaling in macrophages
DM Underhill, A Ozinsky, KD Smith, A Aderem
Proceedings of the National Academy of Sciences 96 (25), 14459-14463, 1999
Systems biology approach predicts immunogenicity of the yellow fever vaccine in humans
TD Querec, RS Akondy, EK Lee, W Cao, HI Nakaya, D Teuwen, A Pirani, ...
Nature immunology 10 (1), 116, 2009
Caspase-1-induced pyroptosis is an innate immune effector mechanism against intracellular bacteria
EA Miao, IA Leaf, PM Treuting, DP Mao, M Dors, A Sarkar, SE Warren, ...
Nature immunology 11 (12), 1136-1142, 2010
Pyogenic bacterial infections in humans with IRAK-4 deficiency
C Picard, A Puel, M Bonnet, CL Ku, J Bustamante, K Yang, C Soudais, ...
Science 299 (5615), 2076-2079, 2003
Toll-like receptor 5 recognizes a conserved site on flagellin required for protofilament formation and bacterial motility
KD Smith, E Andersen-Nissen, F Hayashi, K Strobe, MA Bergman, ...
Nature immunology 4 (12), 1247-1253, 2003
Leptospiral lipopolysaccharide activates cells through a TLR2-dependent mechanism
C Werts, RI Tapping, JC Mathison, TH Chuang, V Kravchenko, ...
Nature immunology 2 (4), 346-352, 2001
MARCKS is an actin filament crosslinking protein regulated by protein kinase C and calcium–calmodulin
JH Hartwig, M Thelen, A Resen, PA Janmey, AC Nairn, A Aderem
Nature 356 (6370), 618-622, 1992
The myristoyl-electrostatic switch: a modulator of reversible protein-membrane interactions
S McLaughlin, A Aderem
Trends in biochemical sciences 20 (7), 272-276, 1995
Caspase‐1‐induced pyroptotic cell death
EA Miao, JV Rajan, A Aderem
Immunological reviews 243 (1), 206-214, 2011
Systems biology approaches identify ATF3 as a negative regulator of Toll-like receptor 4
M Gilchrist, V Thorsson, B Li, AG Rust, M Korb, K Kennedy, T Hai, ...
Nature 441 (7090), 173-178, 2006
Innate immune detection of the type III secretion apparatus through the NLRC4 inflammasome
EA Miao, DP Mao, N Yudkovsky, R Bonneau, CG Lorang, SE Warren, ...
Proceedings of the National Academy of Sciences 107 (7), 3076-3080, 2010
A common dominant TLR5 stop codon polymorphism abolishes flagellin signaling and is associated with susceptibility to legionnaires' disease
TR Hawn, A Verbon, KD Lettinga, LP Zhao, SS Li, RJ Laws, SJ Skerrett, ...
Journal of Experimental Medicine 198 (10), 1563-1572, 2003
The system can't perform the operation now. Try again later.
Articles 1–20