Modeling T-cell acute lymphoblastic leukemia induced by the SCL and LMO1 oncogenes M Tremblay, CS Tremblay, S Herblot, PD Aplan, J Hébert, C Perreault, ... Genes & development 24 (11), 1093-1105, 2010 | 138 | 2010 |
ZEB2 drives immature T-cell lymphoblastic leukaemia development via enhanced tumour-initiating potential and IL-7 receptor signalling S Goossens, E Radaelli, O Blanchet, K Durinck, J Van der Meulen, ... Nature communications 6 (1), 5794, 2015 | 94 | 2015 |
SCL, LMO1 and Notch1 Reprogram Thymocytes into Self-Renewing Cells B Gerby, CS Tremblay, M Tremblay, S Rojas-Sutterlin, S Herblot, J Hébert, ... PLoS genetics 10 (12), e1004768, 2014 | 82 | 2014 |
Requirement for Lyl1 in a model of Lmo2-driven early T-cell precursor ALL MP McCormack, BJ Shields, JT Jackson, C Nasa, W Shi, NJ Slater, ... Blood, The Journal of the American Society of Hematology 122 (12), 2093-2103, 2013 | 77 | 2013 |
HES1 is a novel interactor of the Fanconi anemia core complex CS Tremblay, FF Huang, O Habi, CC Huard, C Godin, G Lévesque, ... Blood, The Journal of the American Society of Hematology 112 (5), 2062-2070, 2008 | 73 | 2008 |
Loss-of-function mutations of Dynamin 2 promote T-ALL by enhancing IL-7 signalling CS Tremblay, FC Brown, M Collett, J Saw, SK Chiu, SE Sonderegger, ... Leukemia 30 (10), 1993-2001, 2016 | 66 | 2016 |
Conserved IKAROS-regulated genes associated with B-progenitor acute lymphoblastic leukemia outcome MT Witkowski, Y Hu, KG Roberts, JM Boer, MD McKenzie, GJ Liu, ... Journal of Experimental Medicine 214 (3), 773-791, 2017 | 38 | 2017 |
Fanconi anemia proteins interact with CtBP1 and modulate the expression of the Wnt antagonist Dickkopf-1 CC Huard, CS Tremblay, K Helsper, MC Delisle, D Schindler, G Lévesque, ... Blood, The Journal of the American Society of Hematology 121 (10), 1729-1739, 2013 | 32 | 2013 |
The clonal evolution of leukemic stem cells in T-cell acute lymphoblastic leukemia CS Tremblay, DJ Curtis Current opinion in hematology 21 (4), 320-325, 2014 | 29 | 2014 |
Regulation of the Fanconi anemia group C protein through proteolytic modification I Brodeur, I Goulet, CS Tremblay, C Charbonneau, MC Delisle, C Godin, ... Journal of Biological Chemistry 279 (6), 4713-4720, 2004 | 29 | 2004 |
The fanconi anemia core complex acts as a transcriptional co-regulator in hairy enhancer of split 1 signaling CS Tremblay, CC Huard, FF Huang, O Habi, V Bourdages, G Levesque, ... Journal of Biological Chemistry 284 (20), 13384-13395, 2009 | 27 | 2009 |
ZEB2 and LMO2 drive immature T-cell lymphoblastic leukemia via distinct oncogenic mechanisms S Goossens, J Wang, CS Tremblay, J De Medts, S T’Sas, T Nguyen, ... haematologica 104 (8), 1608, 2019 | 26 | 2019 |
Small molecule inhibition of Dynamin-dependent endocytosis targets multiple niche signals and impairs leukemia stem cells CS Tremblay, SK Chiu, J Saw, H McCalmont, V Litalien, J Boyle, ... Nature communications 11 (1), 6211, 2020 | 24 | 2020 |
Restricted cell cycle is essential for clonal evolution and therapeutic resistance of pre-leukemic stem cells CS Tremblay, J Saw, SK Chiu, NC Wong, K Tsyganov, S Ghotb, ... Nature communications 9 (1), 3535, 2018 | 23 | 2018 |
Early T cell differentiation: Lessons from T-cell acute lymphoblastic leukemia CS Tremblay, T Hoang, T Hoang Progress in molecular biology and translational science 92, 121-156, 2010 | 23 | 2010 |
The Fanconi anemia pathway has a dual function in Dickkopf-1 transcriptional repression CC Huard, CS Tremblay, A Magron, G Lévesque, M Carreau Proceedings of the National Academy of Sciences 111 (6), 2152-2157, 2014 | 20 | 2014 |
Inflammatory signals in HSPC development and homeostasis: Too much of a good thing? TC Luis, CS Tremblay, MG Manz, TE North, KY King, GA Challen Experimental hematology 44 (10), 908-912, 2016 | 19 | 2016 |
PUMA promotes apoptosis of hematopoietic progenitors driving leukemic progression in a mouse model of myelodysplasia AA Guirguis, CI Slape, LM Failla, J Saw, CS Tremblay, DR Powell, ... Cell Death & Differentiation 23 (6), 1049-1059, 2016 | 17 | 2016 |
Shared roles for Scl and Lyl1 in murine platelet production and function SK Chiu, SL Orive, MJ Moon, J Saw, S Ellis, BT Kile, Y Huang, D Chacon, ... Blood, The Journal of the American Society of Hematology 134 (10), 826-835, 2019 | 16 | 2019 |
Utility of CRISPR/Cas9 systems in hematology research D Lucas, HA O'Leary, BL Ebert, CA Cowan, CS Tremblay Experimental Hematology 54, 1-3, 2017 | 16 | 2017 |