Scanning ultrasound removes amyloid-β and restores memory in an Alzheimer’s disease mouse model G Leinenga, J Götz Science translational medicine 7 (278), 278ra33-278ra33, 2015 | 551 | 2015 |
Ultrasound treatment of neurological diseases—current and emerging applications G Leinenga, C Langton, R Nisbet, J Götz Nature Reviews Neurology 12 (3), 161-174, 2016 | 234 | 2016 |
Combined effects of scanning ultrasound and a tau-specific single chain antibody in a tau transgenic mouse model RM Nisbet, A Van der Jeugd, G Leinenga, HT Evans, PW Janowicz, ... Brain 140 (5), 1220-1230, 2017 | 182 | 2017 |
Repeated ultrasound treatment of tau transgenic mice clears neuronal tau by autophagy and improves behavioral functions R Pandit, G Leinenga, J Götz Theranostics 9 (13), 3754, 2019 | 93 | 2019 |
What renders TAU toxic J Götz, D Xia, G Leinenga, YL Chew, HR Nicholas Frontiers in neurology 4, 72, 2013 | 88 | 2013 |
Ultrasound-mediated blood-brain barrier opening enhances delivery of therapeutically relevant formats of a tau-specific antibody PW Janowicz, G Leinenga, J Götz, RM Nisbet Scientific reports 9 (1), 9255, 2019 | 65 | 2019 |
A comparative study of the effects of Aducanumab and scanning ultrasound on amyloid plaques and behavior in the APP23 mouse model of Alzheimer disease G Leinenga, WK Koh, J Götz Alzheimer's research & therapy 13, 1-14, 2021 | 59 | 2021 |
Safety and efficacy of scanning ultrasound treatment of aged APP23 mice G Leinenga, J Götz Frontiers in neuroscience 12, 328839, 2018 | 58 | 2018 |
Establishing sheep as an experimental species to validate ultrasound-mediated blood-brain barrier opening for potential therapeutic interventions M Pelekanos, G Leinenga, M Odabaee, M Odabaee, S Saifzadeh, ... Theranostics 8 (9), 2583, 2018 | 38 | 2018 |
Scanning ultrasound (SUS) causes no changes to neuronal excitability and prevents age-related reductions in hippocampal CA1 dendritic structure in wild-type mice RJ Hatch, G Leinenga, J Götz PLoS One 11 (10), e0164278, 2016 | 28 | 2016 |
Scanning ultrasound in the absence of blood-brain barrier opening is not sufficient to clear β-amyloid plaques in the APP23 mouse model of Alzheimer's disease G Leinenga, WK Koh, J Götz Brain Research Bulletin 153, 8-14, 2019 | 25 | 2019 |
A sporadic Alzheimer's blood-brain barrier model for developing ultrasound-mediated delivery of Aducanumab and anti-Tau antibodies JM Wasielewska, JCS Chaves, RL Johnston, LA Milton, D Hernández, ... Theranostics 12 (16), 6826, 2022 | 18 | 2022 |
Claudin-5 binder enhances focused ultrasound-mediated opening in an in vitro blood-brain barrier model L Chen, R Sutharsan, JLF Lee, E Cruz, B Asnicar, T Palliyaguru, ... Theranostics 12 (5), 1952, 2022 | 15 | 2022 |
Modeling ultrasound propagation through material of increasing geometrical complexity M Odabaee, M Odabaee, M Pelekanos, G Leinenga, J Götz Ultrasonics 90, 52-62, 2018 | 13 | 2018 |
Transcriptional signature in microglia isolated from an Alzheimer's disease mouse model treated with scanning ultrasound G Leinenga, LG Bodea, J Schröder, G Sun, Y Zhou, J Song, A Grubman, ... Bioengineering & Translational Medicine 8 (1), e10329, 2023 | 11 | 2023 |
Delivery of antibodies into the brain using focused scanning ultrasound G Leinenga, LG Bodea, WK Koh, RM Nisbet, J Götz JoVE (Journal of Visualized Experiments), e61372, 2020 | 6 | 2020 |
5th International Symposium on Focused Ultrasound: North Bethesda, MD, USA. 28 August-1 September 2016 M Zaaroor, A Sinai, D Goldsher, A Eran, M Nassar, I Schlesinger, J Parker, ... Journal of Therapeutic Ultrasound 4, 1-113, 2016 | 2 | 2016 |
Ultrasound as a treatment modality for neurological diseases G Leinenga, RM Nisbet, J Götz The Medical Journal of Australia 206 (11), 470-471, 2017 | 1 | 2017 |
Scanning ultrasound-mediated memory and functional improvements do not require amyloid-β reduction G Leinenga, XV To, LG Bodea, J Yousef, G Richter-Stretton, T Palliyaguru, ... Molecular Psychiatry, 1-16, 2024 | | 2024 |
Scanning ultrasound improves memory and enhances functional outcomes in Alzheimer mice in the absence of amyloid-beta reduction G Leinenga, XV To, L Bodea, J Yousef, G Richter-Stretton, T Palliyaguru, ... | | 2023 |