Lai Yue Angeline Chan
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Engineering pro-angiogenic peptides using stable, disulfide-rich cyclic scaffolds
LY Chan, S Gunasekera, ST Henriques, NF Worth, SJ Le, RJ Clark, ...
Blood, The Journal of the American Society of Hematology 118 (25), 6709-6717, 2011
High-affinity cyclic peptide matriptase inhibitors
P Quimbar, U Malik, CP Sommerhoff, Q Kaas, LY Chan, YH Huang, ...
Journal of Biological Chemistry 288 (19), 13885-13896, 2013
Cyclic peptides arising by evolutionary parallelism via asparaginyl-endopeptidase–mediated biosynthesis
JS Mylne, LY Chan, AH Chanson, NL Daly, H Schaefer, TL Bailey, ...
The Plant Cell 24 (7), 2765-2778, 2012
Cyclotides as grafting frameworks for protein engineering and drug design applications
AG Poth, LY Chan, DJ Craik
Peptide Science 100 (5), 480-491, 2013
Molecular basis for the production of cyclic peptides by plant asparaginyl endopeptidases
MA Jackson, EK Gilding, T Shafee, KS Harris, Q Kaas, S Poon, K Yap, ...
Nature communications 9 (1), 2411, 2018
Semienzymatic cyclization of disulfide-rich peptides using Sortase A
X Jia, S Kwon, CIA Wang, YH Huang, LY Chan, CC Tan, KJ Rosengren, ...
Journal of Biological Chemistry 289 (10), 6627-6638, 2014
Carcinogenic parasite secretes growth factor that accelerates wound healing and potentially promotes neoplasia
MJ Smout, J Sotillo, T Laha, A Papatpremsiri, G Rinaldi, RN Pimenta, ...
PLoS pathogens 11 (10), e1005209, 2015
Cyclization of the antimicrobial peptide gomesin with native chemical ligation: influences on stability and bioactivity
LY Chan, VM Zhang, Y Huang, NC Waters, PS Bansal, DJ Craik, NL Daly
ChemBioChem 14 (5), 617-624, 2013
Isolation and characterization of cytotoxic cyclotides from Viola philippica
W He, LY Chan, G Zeng, NL Daly, DJ Craik, N Tan
Peptides 32 (8), 1719-1723, 2011
Dual-targeting anti-angiogenic cyclic peptides as potential drug leads for cancer therapy
LY Chan, DJ Craik, NL Daly
Scientific reports 6 (1), 35347, 2016
Identification, Characterization, and Three-Dimensional Structure of the Novel Circular Bacteriocin, Enterocin NKR-5-3B, from Enterococcus faecium
K Himeno, KJ Rosengren, T Inoue, RH Perez, ML Colgrave, HS Lee, ...
Biochemistry 54 (31), 4863-4876, 2015
A bifunctional asparaginyl endopeptidase efficiently catalyzes both cleavage and cyclization of cyclic trypsin inhibitors
J Du, K Yap, LY Chan, FBH Rehm, FY Looi, AG Poth, EK Gilding, Q Kaas, ...
Nature Communications 11 (1), 1575, 2020
Using the MCoTI-II cyclotide scaffold to design a stable cyclic peptide antagonist of SET, a protein overexpressed in human cancer
C D’Souza, ST Henriques, CK Wang, O Cheneval, LY Chan, NJ Bokil, ...
Biochemistry 55 (2), 396-405, 2016
Cyclic thrombospondin-1 mimetics: grafting of a thrombospondin sequence into circular disulfide-rich frameworks to inhibit endothelial cell migration
LY Chan, DJ Craik, NL Daly
Bioscience reports 35 (6), e00270, 2015
Isolation and Characterization of Peptides from Momordica cochinchinensis Seeds
LY Chan, CKL Wang, JM Major, KP Greenwood, RJ Lewis, DJ Craik, ...
Journal of natural products 72 (8), 1453-1458, 2009
Redesigned spider peptide with improved antimicrobial and anticancer properties
S Troeira Henriques, N Lawrence, S Chaousis, AS Ravipati, O Cheneval, ...
ACS Chemical Biology 12 (9), 2324-2334, 2017
Short cationic peptide derived from Archaea with dual antibacterial properties and anti-infective potential
ES Candido, MH Cardoso, LY Chan, MDT Torres, KGN Oshiro, WF Porto, ...
ACS infectious diseases 5 (7), 1081-1086, 2019
A Computationally Designed Peptide Derived from Escherichia coli as a Potential Drug Template for Antibacterial and Antibiofilm Therapies
MH Cardoso, ES Candido, LY Chan, M Der Torossian Torres, KGN Oshiro, ...
ACS infectious diseases 4 (12), 1727-1736, 2018
The role of disulfide bonds in structure and activity of chlorotoxin
PG Ojeda, LY Chan, AG Poth, CK Wang, DJ Craik
Future medicinal chemistry 6 (15), 1617-1628, 2014
Discovery and mechanistic studies of cytotoxic cyclotides from the medicinal herb Hybanthus enneaspermus
Q Du, LY Chan, EK Gilding, ST Henriques, ND Condon, AS Ravipati, ...
Journal of Biological Chemistry 295 (32), 10911-10925, 2020
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