| 3D self-organized microvascular model of the human blood-brain barrier with endothelial cells, pericytes and astrocytes M Campisi, Y Shin, T Osaki, C Hajal, V Chiono, RD Kamm Biomaterials 180, 117-129, 2018 | 567 | 2018 |
| Inflamed neutrophils sequestered at entrapped tumor cells via chemotactic confinement promote tumor cell extravasation MB Chen, C Hajal, DC Benjamin, C Yu, H Azizgolshani, RO Hynes, ... Proceedings of the National Academy of Sciences 115 (27), 7022-7027, 2018 | 147 | 2018 |
| Dynamic interplay between tumour, stroma and immune system can drive or prevent tumour progression RJ Seager, C Hajal, F Spill, RD Kamm, MH Zaman Convergent science physical oncology 3 (3), 034002, 2017 | 137 | 2017 |
| Engineered human blood–brain barrier microfluidic model for vascular permeability analyses C Hajal, GS Offeddu, Y Shin, S Zhang, O Morozova, D Hickman, ... Nature protocols 17 (1), 95-128, 2022 | 93 | 2022 |
| EGFR and HER2 activate rigidity sensing only on rigid matrices M Saxena, S Liu, B Yang, C Hajal, R Changede, J Hu, H Wolfenson, ... Nature materials 16 (7), 775-781, 2017 | 86 | 2017 |
| Biology and models of the blood–brain barrier C Hajal, B Le Roi, RD Kamm, BM Maoz Annual review of biomedical engineering 23, 359-384, 2021 | 80 | 2021 |
| In vitro models of molecular and nano-particle transport across the blood-brain barrier C Hajal, M Campisi, C Mattu, V Chiono, RD Kamm Biomicrofluidics 12 (4), 2018 | 70 | 2018 |
| Pericytes contribute to dysfunction in a human 3D model of placental microvasculature through VEGF‐Ang‐Tie2 signaling K Haase, MR Gillrie, C Hajal, RD Kamm Advanced Science 6 (23), 1900878, 2019 | 65 | 2019 |
| Epithelial-mesenchymal transition induces podocalyxin to promote extravasation via ezrin signaling J Fröse, MB Chen, KE Hebron, F Reinhardt, C Hajal, A Zijlstra, RD Kamm, ... Cell reports 24 (4), 962-972, 2018 | 61 | 2018 |
| A predictive microfluidic model of human glioblastoma to assess trafficking of blood–brain barrier-penetrant nanoparticles JP Straehla, C Hajal, HC Safford, GS Offeddu, N Boehnke, TG Dacoba, ... Proceedings of the National Academy of Sciences 119 (23), e2118697119, 2022 | 50 | 2022 |
| The cancer glycocalyx mediates intravascular adhesion and extravasation during metastatic dissemination GS Offeddu, C Hajal, CR Foley, Z Wan, L Ibrahim, MF Coughlin, ... Communications biology 4 (1), 255, 2021 | 49* | 2021 |
| The effects of luminal and trans-endothelial fluid flows on the extravasation and tissue invasion of tumor cells in a 3D in vitro microvascular platform C Hajal, L Ibrahim, JC Serrano, GS Offeddu, RD Kamm Biomaterials 265, 120470, 2021 | 49 | 2021 |
| The CCL2-CCR2 astrocyte-cancer cell axis in tumor extravasation at the brain C Hajal, Y Shin, L Li, JC Serrano, T Jacks, RD Kamm Science advances 7 (26), eabg8139, 2021 | 48 | 2021 |
| Omentum-on-a-chip: A multicellular, vascularized microfluidic model of the human peritoneum for the study of ovarian cancer metastases LI Ibrahim, C Hajal, GS Offeddu, MR Gillrie, RD Kamm Biomaterials 288, 121728, 2022 | 23 | 2022 |
| Classical and non-classical fibrosis phenotypes are revealed by lung and cardiac specific microvessels on-chip A Akinbote, VB Sastre, R Visone, C Hajal, D Cobanaglu, K Haase Frontiers in Physiology, 1622, 2021 | 13* | 2021 |
| Blood-brain barrier model on a microfluidic chip for the study of tumor cell extravasation C Hajal Massachusetts Institute of Technology, 2018 | 3 | 2018 |
| DDEL-04. ENGINEERED NANOCARRIERS TO ENHANCE DRUG DELIVERY ACROSS THE BLOOD-BRAIN BARRIER JP Straehla, C Hajal, H Safford, G Offeddu, J Wyckoff, RD Kamm, ... Neuro-Oncology 22 (Suppl 3), iii284, 2020 | 1 | 2020 |
| THER-15. FUNCTIONALIZED NANOPARTICLE TRAFFICKING ASSESSED IN A NOVEL MICROFLUIDIC MODEL OF THE BLOOD-BRAIN BARRIER WITH HIGH GRADE GLIOMA SPHEROIDS JP Straehla, C Hajal, T Dacoba, RD Kamm, PT Hammond Neuro-Oncology 21 (Suppl 2), ii117, 2019 | 1 | 2019 |
| DDDR-09. FUNCTIONAL GENOMICS AND CHEMOTHERAPY RESISTANCE SCREENING IDENTIFIES BIOMARKERS AND TARGETABLE MECHANISMS OF CCNU RESISTANCE IN GLIOMAS C Hajal, S Dalin, G Raskind, M Cusick, S Malinowski, J Ito, C Bossi, ... Neuro-Oncology 25 (Supplement_5), v106-v107, 2023 | | 2023 |
| TMOD-11. A PREDICTIVE MICROFLUIDIC MODEL OF VASCULARIZED GLIOMA TUMORS TO ASSESS TRAFFICKING OF THERAPEUTICS ACROSS THE BLOOD-BRAIN BARRIER C Hajal, JP Straehla, GS Offeddu, H Safford, PT Hammond, RD Kamm Neuro-Oncology 23 (Suppl 6), vi217–vi218, 2021 | | 2021 |
Roger D. KammCecil and Ida Green Distinguished Professor of Biological and Mechanical EngineeringVerified email at mit.edu
