Inhibition of glycolysis modulates prednisolone resistance in acute lymphoblastic leukemia cells E Hulleman, KM Kazemier, A Holleman, DJ VanderWeele, CM Rudin, ... Blood, The Journal of the American Society of Hematology 113 (9), 2014-2021, 2009 | 257 | 2009 |
Activity of durvalumab plus olaparib in metastatic castration-resistant prostate cancer in men with and without DNA damage repair mutations F Karzai, D VanderWeele, RA Madan, H Owens, LM Cordes, A Hankin, ... Journal for immunotherapy of cancer 6, 1-12, 2018 | 243 | 2018 |
Inhibition of glutathione synthesis reverses Bcl-2-mediated cisplatin resistance CM Rudin, Z Yang, LM Schumaker, DJ VanderWeele, K Newkirk, ... Cancer research 63 (2), 312-318, 2003 | 228 | 2003 |
Akt up-regulation increases resistance to microtubule-directed chemotherapeutic agents through mammalian target of rapamycin DJ VanderWeele, R Zhou, CM Rudin Molecular cancer therapeutics 3 (12), 1605-1613, 2004 | 130 | 2004 |
Past, current, and future of immunotherapies for prostate cancer AN Boettcher, A Usman, A Morgans, DJ VanderWeele, J Sosman, JD Wu Frontiers in oncology 9, 884, 2019 | 105 | 2019 |
Bcl-x L complements Saccharomyces cerevisiae genes that facilitate the switch from glycolytic to oxidative metabolism MG Vander Heiden, JS Choy, DJ VanderWeele, JL Brace, MH Harris, ... Journal of Biological Chemistry 277 (47), 44870-44876, 2002 | 83 | 2002 |
Accelerating precision medicine in metastatic prostate cancer J Mateo, R McKay, W Abida, R Aggarwal, J Alumkal, A Alva, F Feng, ... Nature cancer 1 (11), 1041-1053, 2020 | 56 | 2020 |
Quantitative Multiparametric MRI Features and PTEN Expression of Peripheral Zone Prostate Cancer: A Pilot Study SM McCann, Y Jiang, X Fan, J Wang, T Antic, F Prior, D VanderWeele, ... American Journal of Roentgenology 206 (3), 559-565, 2016 | 56 | 2016 |
Low‐grade prostate cancer diverges early from high grade and metastatic disease DJ VanderWeele, CD Brown, JB Taxy, M Gillard, DM Hatcher, WR Tom, ... Cancer science 105 (8), 1079-1085, 2014 | 55 | 2014 |
Nascent prostate cancer heterogeneity drives evolution and resistance to intense hormonal therapy S Wilkinson, H Ye, F Karzai, SA Harmon, NT Terrigino, DJ VanderWeele, ... European urology 80 (6), 746-757, 2021 | 53 | 2021 |
Quantitative characterization of androgen receptor protein expression and cellular localization in circulating tumor cells from patients with metastatic castration-resistant … EE Reyes, DJ VanderWeele, M Isikbay, R Duggan, A Campanile, ... Journal of translational medicine 12, 1-15, 2014 | 50 | 2014 |
Targeting the PI3K/AKT pathway overcomes enzalutamide resistance by inhibiting induction of the glucocorticoid receptor R Adelaiye-Ogala, BE Gryder, YTM Nguyen, AN Alilin, AR Grayson, ... Molecular cancer therapeutics 19 (7), 1436-1447, 2020 | 41 | 2020 |
Svf1 inhibits reactive oxygen species generation and promotes survival under conditions of oxidative stress in Saccharomyces cerevisiae JL Brace, DJ VanderWeele, CM Rudin Yeast 22 (8), 641-652, 2005 | 34 | 2005 |
Circulating tumor cells capture disease evolution in advanced prostate cancer J Lack, M Gillard, M Cam, GP Paner, DJ VanderWeele Journal of translational medicine 15, 1-8, 2017 | 33 | 2017 |
Contemporary population-based comparison of localized ductal adenocarcinoma and high-risk acinar adenocarcinoma of the prostate VT Packiam, SG Patel, JJ Pariser, KA Richards, AB Weiner, GP Paner, ... Urology 86 (4), 777-782, 2015 | 33 | 2015 |
Integrative genomic analysis of coincident cancer foci implicates CTNNB1 and PTEN alterations in ductal prostate cancer M Gillard, J Lack, A Pontier, D Gandla, D Hatcher, AG Sowalsky, ... European urology focus 5 (3), 433-442, 2019 | 31 | 2019 |
Sequential prostate magnetic resonance imaging in newly diagnosed high-risk prostate cancer treated with neoadjuvant enzalutamide is predictive of therapeutic response F Karzai, SM Walker, S Wilkinson, RA Madan, JH Shih, MJ Merino, ... Clinical Cancer Research 27 (2), 429-437, 2021 | 26 | 2021 |
A case report of multiple primary prostate tumors with differential drug sensitivity S Wilkinson, SA Harmon, NT Terrigino, F Karzai, PA Pinto, RA Madan, ... Nature communications 11 (1), 837, 2020 | 26 | 2020 |
Genomic heterogeneity within individual prostate cancer foci impacts predictive biomarkers of targeted therapy DJ VanderWeele, R Finney, K Katayama, M Gillard, G Paner, S Imoto, ... European urology focus 5 (3), 416-424, 2019 | 25 | 2019 |
Mammalian target of rapamycin promotes vincristine resistance through multiple mechanisms independent of maintained glycolytic rate DJ VanderWeele, CM Rudin Molecular cancer research 3 (11), 635-644, 2005 | 18 | 2005 |