Anne Hersey
Anne Hersey
Verified email at ebi.ac.uk
TitleCited byYear
ChEMBL: a large-scale bioactivity database for drug discovery
A Gaulton, LJ Bellis, AP Bento, J Chambers, M Davies, A Hersey, Y Light, ...
Nucleic acids research 40 (D1), D1100-D1107, 2012
22512012
The ChEMBL bioactivity database: an update
AP Bento, A Gaulton, A Hersey, LJ Bellis, J Chambers, M Davies, ...
Nucleic acids research 42 (D1), D1083-D1090, 2014
10392014
A comprehensive map of molecular drug targets
R Santos, O Ursu, A Gaulton, AP Bento, RS Donadi, CG Bologa, ...
Nature reviews Drug discovery 16 (1), 19, 2017
6562017
The ChEMBL database in 2017
A Gaulton, A Hersey, M Nowotka, AP Bento, J Chambers, D Mendez, ...
Nucleic acids research 45 (D1), D945-D954, 2017
5602017
Evaluation of human intestinal absorption data and subsequent derivation of a quantitative structure–activity relationship (QSAR) with the Abraham descriptors
YH Zhao, J Le, MH Abraham, A Hersey, PJ Eddershaw, CN Luscombe, ...
Journal of pharmaceutical sciences 90 (6), 749-784, 2001
4652001
Rate-limited steps of human oral absorption and QSAR studies
YH Zhao, MH Abraham, J Le, A Hersey, CN Luscombe, G Beck, ...
Pharmaceutical research 19 (10), 1446-1457, 2002
4512002
Estimation of molecular linear free energy relation descriptors using a group contribution approach
JA Platts, D Butina, MH Abraham, A Hersey
Journal of Chemical Information and Computer Sciences 39 (5), 835-845, 1999
4211999
Probing the links between in vitro potency, ADMET and physicochemical parameters
MP Gleeson, A Hersey, D Montanari, J Overington
Nature reviews Drug discovery 10 (3), 197-208, 2011
3402011
Correlation and prediction of a large blood–brain distribution data set—an LFER study
JA Platts, MH Abraham, YH Zhao, A Hersey, L Ijaz, D Butina
European journal of medicinal chemistry 36 (9), 719-730, 2001
2122001
Open Targets: a platform for therapeutic target identification and validation
G Koscielny, P An, D Carvalho-Silva, JA Cham, L Fumis, R Gasparyan, ...
Nucleic acids research 45 (D1), D985-D994, 2017
1632017
Improving the in vitro prediction of in vivo central nervous system penetration: integrating permeability, P-glycoprotein efflux, and free fractions in blood and brain
SG Summerfield, AJ Stevens, L Cutler, M del Carmen Osuna, ...
Journal of Pharmacology and Experimental Therapeutics 316 (3), 1282-1290, 2006
1582006
X-ray Crystal Structure of Human Dopamine Sulfotransferase, SULT1A3 MOLECULAR MODELING AND QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP ANALYSIS DEMONSTRATE A MOLECULAR BASIS …
R Dajani, A Cleasby, M Neu, AJ Wonacott, H Jhoti, AM Hood, S Modi, ...
Journal of Biological Chemistry 274 (53), 37862-37868, 1999
1561999
Estimation of molecular linear free energy relationship descriptors by a group contribution approach. 2. Prediction of partition coefficients
JA Platts, MH Abraham, D Butina, A Hersey
Journal of Chemical Information and Computer Sciences 40 (1), 71-80, 2000
1512000
In-silico ADME models: a general assessment of their utility in drug discovery applications
M Paul Gleeson, A Hersey, S Hannongbua
Current topics in medicinal chemistry 11 (4), 358-381, 2011
1222011
Evaluation of rat intestinal absorption data and correlation with human intestinal absorption
YH Zhao, MH Abraham, J Le, A Hersey, CN Luscombe, G Beck, ...
European journal of medicinal chemistry 38 (3), 233-243, 2003
1082003
UniChem: a unified chemical structure cross-referencing and identifier tracking system
J Chambers, M Davies, A Gaulton, A Hersey, S Velankar, R Petryszak, ...
Journal of cheminformatics 5 (1), 3, 2013
1052013
Correlation and estimation of gas–chloroform and water–chloroform partition coefficients by a linear free energy relationship method
MH Abraham, JA Platts, A Hersey, AJ Leo, RW Taft
Journal of pharmaceutical sciences 88 (7), 670-679, 1999
951999
Unexplored therapeutic opportunities in the human genome
TI Oprea, CG Bologa, S Brunak, A Campbell, GN Gan, A Gaulton, ...
Nature reviews Drug discovery 17 (5), 317, 2018
892018
Pharos: collating protein information to shed light on the druggable genome
DT Nguyen, S Mathias, C Bologa, S Brunak, N Fernandez, A Gaulton, ...
Nucleic acids research 45 (D1), D995-D1002, 2017
882017
SureChEMBL: a large-scale, chemically annotated patent document database
G Papadatos, M Davies, N Dedman, J Chambers, A Gaulton, J Siddle, ...
Nucleic acids research 44 (D1), D1220-D1228, 2016
882016
The system can't perform the operation now. Try again later.
Articles 1–20