Endogenous formaldehyde is a hematopoietic stem cell genotoxin and metabolic carcinogen LB Pontel, IV Rosado, G Burgos-Barragan, JI Garaycoechea, R Yu, ... Molecular cell 60 (1), 177-188, 2015 | 338 | 2015 |
Mammals divert endogenous genotoxic formaldehyde into one-carbon metabolism G Burgos-Barragan, N Wit, J Meiser, FA Dingler, M Pietzke, L Mulderrig, ... Nature 548 (7669), 549-554, 2017 | 280 | 2017 |
Formaldehyde metabolism and its impact on human health H Reingruber, LB Pontel Current opinion in toxicology 9, 28-34, 2018 | 136 | 2018 |
Development of a general aza-cope reaction trigger applied to fluorescence imaging of formaldehyde in living cells KJ Bruemmer, RR Walvoord, TF Brewer, G Burgos-Barragan, N Wit, ... Journal of the American Chemical Society 139 (15), 5338-5350, 2017 | 127 | 2017 |
GolS controls the response to gold by the hierarchical induction of Salmonella‐specific genes that include a CBA efflux‐coding operon LB Pontel, MEP Audero, M Espariz, SK Checa, FC Soncini Molecular microbiology 66 (3), 814-825, 2007 | 127 | 2007 |
Alternative periplasmic copper‐resistance mechanisms in Gram negative bacteria LB Pontel, FC Soncini Molecular microbiology 73 (2), 212-225, 2009 | 121 | 2009 |
Two aldehyde clearance systems are essential to prevent lethal formaldehyde accumulation in mice and humans FA Dingler, M Wang, A Mu, CL Millington, N Oberbeck, S Watcham, ... Molecular cell 80 (6), 996-1012. e9, 2020 | 113 | 2020 |
Dissecting the Salmonella response to copper M Espariz, SK Checa, MEP Audero, LB Pontel, FC Soncini Microbiology 153 (9), 2989-2997, 2007 | 109 | 2007 |
Regulation of magnesium homeostasis in Salmonella: Mg2+ targets the mgtA transcript for degradation by RNase E SV Spinelli, LB Pontel, E García Véscovi, FC Soncini FEMS microbiology letters 280 (2), 226-234, 2008 | 76 | 2008 |
Endogenous formaldehyde scavenges cellular glutathione resulting in redox disruption and cytotoxicity C Umansky, AE Morellato, M Rieckher, MA Scheidegger, MR Martinefski, ... Nature communications 13 (1), 745, 2022 | 47 | 2022 |
The toxic side of one-carbon metabolism and epigenetics AE Morellato, C Umansky, LB Pontel Redox Biology 40, 101850, 2021 | 42 | 2021 |
Identification of a Salmonella ancillary copper detoxification mechanism by a comparative analysis of the genome-wide transcriptional response to copper and zinc … LB Pontel, NL Scampoli, S Porwollik, SK Checa, M McClelland, ... Microbiology 160 (8), 1659-1669, 2014 | 41 | 2014 |
Compartment and signal-specific codependence in the transcriptional control of Salmonella periplasmic copper homeostasis A Pezza, LB Pontel, C López, FC Soncini Proceedings of the National Academy of Sciences 113 (41), 11573-11578, 2016 | 34 | 2016 |
Acute lymphoblastic leukemia necessitates GSH-dependent ferroptosis defenses to overcome FSP1-epigenetic silencing LB Pontel, A Bueno-Costa, AE Morellato, JC Santos, G Roué, M Esteller Redox biology 55, 102408, 2022 | 32 | 2022 |
Bacterial copper resistance and virulence LB Pontel, SK Checa, FC Soncini Bacteria-metal interactions, 1-19, 2015 | 17 | 2015 |
Copper Stress Targets the Rcs System To Induce Multiaggregative Behavior in a Copper-Sensitive Salmonella Strain LB Pontel, A Pezza, FC Soncini Journal of bacteriology 192 (23), 6287-6290, 2010 | 16 | 2010 |
Illuminating cellular formaldehyde C Umansky, AE Morellato, LB Pontel Nature Communications 12 (1), 580, 2021 | 10 | 2021 |
Formaldehyde regulates S-adenosylmethionine biosynthesis and one-carbon metabolism VN Pham, KJ Bruemmer, JDW Toh, EJ Ge, L Tenney, CC Ward, ... Science 382 (6670), eabp9201, 2023 | 9 | 2023 |
Xpf suppresses the mutagenic consequences of phagocytosis in Dictyostelium LB Pontel, J Langenick, IV Rosado, XY Zhang, D Traynor, RR Kay, ... Journal of Cell Science 129 (24), 4449-4454, 2016 | 9 | 2016 |
A dimerization interface mediated by functionally critical residues creates interfacial disulfide bonds and copper sites in CueP LA Abriata, LB Pontel, AJ Vila, M Dal Peraro, FC Soncini Journal of inorganic biochemistry 140, 199-201, 2014 | 7 | 2014 |