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Lucas Pontel
Lucas Pontel
Group Leader, IBioBA-MPSP and Josep Carreras Leukaemia Research Institute
Verified email at ibioba-mpsp-conicet.gov.ar
Title
Cited by
Cited by
Year
Endogenous formaldehyde is a hematopoietic stem cell genotoxin and metabolic carcinogen
LB Pontel, IV Rosado, G Burgos-Barragan, JI Garaycoechea, R Yu, ...
Molecular cell 60 (1), 177-188, 2015
3352015
Mammals divert endogenous genotoxic formaldehyde into one-carbon metabolism
G Burgos-Barragan, N Wit, J Meiser, FA Dingler, M Pietzke, L Mulderrig, ...
Nature 548 (7669), 549-554, 2017
2772017
Formaldehyde metabolism and its impact on human health
H Reingruber, LB Pontel
Current opinion in toxicology 9, 28-34, 2018
1322018
GolS controls the response to gold by the hierarchical induction of Salmonella‐specific genes that include a CBA efflux‐coding operon
LB Pontel, MEP Audero, M Espariz, SK Checa, FC Soncini
Molecular microbiology 66 (3), 814-825, 2007
1272007
Development of a general aza-cope reaction trigger applied to fluorescence imaging of formaldehyde in living cells
KJ Bruemmer, RR Walvoord, TF Brewer, G Burgos-Barragan, N Wit, ...
Journal of the American Chemical Society 139 (15), 5338-5350, 2017
1252017
Alternative periplasmic copper‐resistance mechanisms in Gram negative bacteria
LB Pontel, FC Soncini
Molecular microbiology 73 (2), 212-225, 2009
1212009
Two aldehyde clearance systems are essential to prevent lethal formaldehyde accumulation in mice and humans
FA Dingler, M Wang, A Mu, CL Millington, N Oberbeck, S Watcham, ...
Molecular cell 80 (6), 996-1012. e9, 2020
1122020
Dissecting the Salmonella response to copper
M Espariz, SK Checa, MEP Audero, LB Pontel, FC Soncini
Microbiology 153 (9), 2989-2997, 2007
1092007
Regulation of magnesium homeostasis in Salmonella: Mg2+ targets the mgtA transcript for degradation by RNase E
SV Spinelli, LB Pontel, E García Véscovi, FC Soncini
FEMS microbiology letters 280 (2), 226-234, 2008
762008
Endogenous formaldehyde scavenges cellular glutathione resulting in redox disruption and cytotoxicity
C Umansky, AE Morellato, M Rieckher, MA Scheidegger, MR Martinefski, ...
Nature communications 13 (1), 745, 2022
472022
The toxic side of one-carbon metabolism and epigenetics
AE Morellato, C Umansky, LB Pontel
Redox Biology 40, 101850, 2021
422021
Identification of a Salmonella ancillary copper detoxification mechanism by a comparative analysis of the genome-wide transcriptional response to copper and zinc …
LB Pontel, NL Scampoli, S Porwollik, SK Checa, M McClelland, ...
Microbiology 160 (8), 1659-1669, 2014
412014
Compartment and signal-specific codependence in the transcriptional control of Salmonella periplasmic copper homeostasis
A Pezza, LB Pontel, C López, FC Soncini
Proceedings of the National Academy of Sciences 113 (41), 11573-11578, 2016
342016
Acute lymphoblastic leukemia necessitates GSH-dependent ferroptosis defenses to overcome FSP1-epigenetic silencing
LB Pontel, A Bueno-Costa, AE Morellato, JC Santos, G Roué, M Esteller
Redox biology 55, 102408, 2022
322022
Bacterial copper resistance and virulence
LB Pontel, SK Checa, FC Soncini
Bacteria-metal interactions, 1-19, 2015
172015
Copper Stress Targets the Rcs System To Induce Multiaggregative Behavior in a Copper-Sensitive Salmonella Strain
LB Pontel, A Pezza, FC Soncini
Journal of bacteriology 192 (23), 6287-6290, 2010
162010
Illuminating cellular formaldehyde
C Umansky, AE Morellato, LB Pontel
Nature Communications 12 (1), 580, 2021
102021
Formaldehyde regulates S-adenosylmethionine biosynthesis and one-carbon metabolism
VN Pham, KJ Bruemmer, JDW Toh, EJ Ge, L Tenney, CC Ward, ...
Science 382 (6670), eabp9201, 2023
82023
Xpf suppresses the mutagenic consequences of phagocytosis in Dictyostelium
LB Pontel, J Langenick, IV Rosado, XY Zhang, D Traynor, RR Kay, ...
Journal of Cell Science 129 (24), 4449-4454, 2016
82016
A dimerization interface mediated by functionally critical residues creates interfacial disulfide bonds and copper sites in CueP
LA Abriata, LB Pontel, AJ Vila, M Dal Peraro, FC Soncini
Journal of inorganic biochemistry 140, 199-201, 2014
72014
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