| Formation of pluripotent stem cells in the mammalian embryo depends on the POU transcription factor Oct4 J Nichols, B Zevnik, K Anastassiadis, H Niwa, D Klewe-Nebenius, ... Cell 95 (3), 379-391, 1998 | 4350 | 1998 |
| Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells I Chambers, D Colby, M Robertson, J Nichols, S Lee, S Tweedie, A Smith Cell 113 (5), 643-655, 2003 | 4329 | 2003 |
| The ground state of embryonic stem cell self-renewal QL Ying, J Wray, J Nichols, L Batlle-Morera, B Doble, J Woodgett, ... nature 453 (7194), 519-523, 2008 | 3885 | 2008 |
| BMP induction of Id proteins suppresses differentiation and sustains embryonic stem cell self-renewal in collaboration with STAT3 QL Ying, J Nichols, I Chambers, A Smith Cell 115 (3), 281-292, 2003 | 2735 | 2003 |
| Changing potency by spontaneous fusion QL Ying, J Nichols, EP Evans, AG Smith Nature 416 (6880), 545-548, 2002 | 2108 | 2002 |
| Naive and primed pluripotent states J Nichols, A Smith Cell stem cell 4 (6), 487-492, 2009 | 2082 | 2009 |
| Nanog safeguards pluripotency and mediates germline development I Chambers, J Silva, D Colby, J Nichols, B Nijmeijer, M Robertson, ... Nature 450 (7173), 1230-1234, 2007 | 1784 | 2007 |
| Nanog is the gateway to the pluripotent ground state J Silva, J Nichols, TW Theunissen, G Guo, AL van Oosten, O Barrandon, ... Cell 138 (4), 722-737, 2009 | 1253 | 2009 |
| Evaluating the effects of SARS-CoV-2 spike mutation D614G on transmissibility and pathogenicity E Volz, V Hill, JT McCrone, A Price, D Jorgensen, Á O’Toole, J Southgate, ... Cell 184 (1), 64-75. e11, 2021 | 1058 | 2021 |
| Promotion of reprogramming to ground state pluripotency by signal inhibition J Silva, O Barrandon, J Nichols, J Kawaguchi, TW Theunissen, A Smith PLoS biology 6 (10), e253, 2008 | 1033 | 2008 |
| Resetting transcription factor control circuitry toward ground-state pluripotency in human Y Takashima, G Guo, R Loos, J Nichols, G Ficz, F Krueger, D Oxley, ... Cell 158 (6), 1254-1269, 2014 | 975 | 2014 |
| The transcriptional and epigenomic foundations of ground state pluripotency H Marks, T Kalkan, R Menafra, S Denissov, K Jones, H Hofemeister, ... Cell 149 (3), 590-604, 2012 | 952 | 2012 |
| Klf4 reverts developmentally programmed restriction of ground state pluripotency G Guo, J Yang, J Nichols, JS Hall, I Eyres, W Mansfield, A Smith Oxford University Press for The Company of Biologists Limited 136 (7), 1063-1069, 2009 | 852 | 2009 |
| Hospital admission and emergency care attendance risk for SARS-CoV-2 delta (B. 1.617. 2) compared with alpha (B. 1.1. 7) variants of concern: a cohort study KA Twohig, T Nyberg, A Zaidi, S Thelwall, MA Sinnathamby, S Aliabadi, ... The Lancet Infectious Diseases 22 (1), 35-42, 2022 | 801 | 2022 |
| Suppression of SHP-2 and ERK signalling promotes self-renewal of mouse embryonic stem cells T Burdon, C Stracey, I Chambers, J Nichols, A Smith Developmental biology 210 (1), 30-43, 1999 | 731 | 1999 |
| A single-cell molecular map of mouse gastrulation and early organogenesis B Pijuan-Sala, JA Griffiths, C Guibentif, TW Hiscock, W Jawaid, ... Nature 566 (7745), 490-495, 2019 | 704 | 2019 |
| Suppression of Erk signalling promotes ground state pluripotency in the mouse embryo J Nichols, J Silva, M Roode, A Smith Development 136 (19), 3215-3222, 2009 | 660 | 2009 |
| Regulated fluctuations in nanog expression mediate cell fate decisions in embryonic stem cells T Kalmar, C Lim, P Hayward, S Muñoz-Descalzo, J Nichols, ... PLoS biology 7 (7), e1000149, 2009 | 641 | 2009 |
| Circulating SARS-CoV-2 spike N439K variants maintain fitness while evading antibody-mediated immunity EC Thomson, LE Rosen, JG Shepherd, R Spreafico, A da Silva Filipe, ... Cell 184 (5), 1171-1187. e20, 2021 | 557 | 2021 |
| Establishment of germ-line-competent embryonic stem (ES) cells using differentiation inhibiting activity J Nichols, EP Evans, AG Smith Development 110 (4), 1341-1348, 1990 | 474 | 1990 |
