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Nathan Zammit
Nathan Zammit
Harvard Medical School
Verified email at hms.harvard.edu
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Cited by
Cited by
Year
MicroRNA-125a and-b inhibit A20 and MAVS to promote inflammation and impair antiviral response in COPD
ACY Hsu, K Dua, MR Starkey, TJ Haw, PM Nair, K Nichol, N Zammit, ...
JCI insight 2 (7), 2017
1092017
Human islets express a marked proinflammatory molecular signature prior to transplantation
MJ Cowley, A Weinberg, NW Zammit, SN Walters, WJ Hawthorne, ...
Cell transplantation 21 (9), 2063-2078, 2012
992012
Nuclear factor κB–inducing kinase activation as a mechanism of pancreatic β cell failure in obesity
EK Malle, NW Zammit, SN Walters, YC Koay, J Wu, BM Tan, ...
Journal of Experimental Medicine 212 (8), 1239-1254, 2015
592015
Denisovan, modern human and mouse TNFAIP3 alleles tune A20 phosphorylation and immunity
NW Zammit, OM Siggs, PE Gray, K Horikawa, DB Langley, SN Walters, ...
Nature immunology 20 (10), 1299-1310, 2019
542019
β cell replacement therapy: the next 10 years
C Schuetz, T Anazawa, SE Cross, L Labriola, RPH Meier, RR Redfield III, ...
Transplantation 102 (2), 215-229, 2018
472018
Spatial and temporal control of CRISPR-Cas9-mediated gene editing delivered via a light-triggered liposome system
YA Aksoy, B Yang, W Chen, T Hung, RP Kuchel, NW Zammit, ST Grey, ...
ACS applied materials & interfaces 12 (47), 52433-52444, 2020
422020
Acute phase proteins are major clients for the chaperone action of α2-macroglobulin in human plasma
AR Wyatt, MR Wilson
Cell Stress and Chaperones 18 (2), 161-170, 2013
402013
A20 as an immune tolerance factor can determine islet transplant outcomes
NW Zammit, SN Walters, KL Seeberger, PJ O’Connell, GS Korbutt, ...
JCI insight 4 (21), 2019
372019
Baculoviral inhibitors of apoptosis repeat containing (BIRC) proteins fine-tune TNF-induced nuclear factor κB and c-Jun N-terminal kinase signalling in mouse pancreatic beta cells
BM Tan, NW Zammit, AO Yam, R Slattery, SN Walters, E Malle, ST Grey
Diabetologia 56, 520-532, 2013
312013
Low-Dose Rapamycin Unmasks the Protective Potential of Targeting Intragraft NF-κB for Islet Transplants.
NW Zammit, BM Tan, SN Walters, D Liuwantara, JE Villanueva, ST Grey
Cell transplantation, 2013
192013
TRAF2 regulates peripheral CD8+ T‐cell and NKT‐cell homeostasis by modulating sensitivity to IL‐15
JE Villanueva, EK Malle, S Gardam, PA Silveira, NW Zammit, SN Walters, ...
European Journal of Immunology 45 (6), 1820-1831, 2015
162015
Emerging roles for A20 in islet biology and pathology
NW Zammit, ST Grey
The Multiple Therapeutic Targets of A20, 141-162, 2014
152014
The retroelement Lx9 puts a brake on the immune response to virus infection
N Bartonicek, R Rouet, J Warren, C Loetsch, GS Rodriguez, S Walters, ...
Nature 608 (7924), 757-765, 2022
82022
Targeted deletion of Traf2 allows immunosuppression-free islet allograft survival in mice
JE Villanueva, SN Walters, M Saito, EK Malle, NW Zammit, KA Watson, ...
Diabetologia 60, 679-689, 2017
82017
Equipping the islet graft for self defence: targeting nuclear factor κB and implications for tolerance
NW Zammit, ST Grey
Current Opinion in Organ Transplantation 23 (1), 97-105, 2018
62018
A zebrafish functional genomics model to investigate the role of human A20 variants in vivo
D Cultrone, NW Zammit, E Self, B Postert, JZR Han, J Bailey, J Warren, ...
Scientific reports 10 (1), 19085, 2020
52020
Selection of a novel AAV2/TNFAIP3 vector for local suppression of islet xenograft inflammation
NW Zammit, KL Seeberger, J Zamerli, SN Walters, L Lisowski, GS Korbutt, ...
Xenotransplantation 28 (3), e12669, 2021
42021
RELA governs a network of islet-specific metabolic genes necessary for beta cell function
NW Zammit, YY Wong, SN Walters, J Warren, SC Barry, ST Grey
Diabetologia 66 (8), 1516-1531, 2023
32023
TNFAIP3 reduction-of-function drives female infertility and CNS inflammation
NW Zammit, J McDowell, J Warren, W Muskovic, J Gamble, YC Shi, ...
Frontiers in Immunology 13, 811525, 2022
32022
The impact of the cytoplasmic ubiquitin ligase TNFAIP3 gene variation on transcription factor NF-κB activation in acute kidney injury
NM Rogers, N Zammit, D Nguyen-Ngo, Y Souilmi, N Minhas, DN Meijles, ...
Kidney International 103 (6), 1105-1119, 2023
2023
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