Martin Scanlon
Martin Scanlon
Professor of Medicinal Chemistry, Monash University
Verified email at - Homepage
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Activation of the pseudokinase MLKL unleashes the four-helix bundle domain to induce membrane localization and necroptotic cell death
JM Hildebrand, MC Tanzer, IS Lucet, SN Young, SK Spall, P Sharma, ...
Proceedings of the National Academy of Sciences 111 (42), 15072-15077, 2014
DSB proteins and bacterial pathogenicity
B Heras, SR Shouldice, M Totsika, MJ Scanlon, MA Schembri, JL Martin
Nature Reviews Microbiology 7 (3), 215-225, 2009
Isolation, Solution Structure, and Insecticidal Activity of Kalata B2, a Circular Protein with a Twist:  Do Möbius Strips Exist in Nature?,
CV Jennings, KJ Rosengren, NL Daly, M Plan, J Stevens, MJ Scanlon, ...
Biochemistry 44 (3), 851-860, 2005
Three-dimensional structure of a cysteine-rich repeat from the low-density lipoprotein receptor
NL Daly, MJ Scanlon, JT Djordjevic, PA Kroon, R Smith
Proceedings of the National Academy of Sciences 92 (14), 6334-6338, 1995
Conformational selection of inhibitors and substrates by proteolytic enzymes: implications for drug design and polypeptide processing
DP Fairlie, JDA Tyndall, RC Reid, AK Wong, G Abbenante, MJ Scanlon, ...
Journal of medicinal chemistry 43 (7), 1271-1281, 2000
The three-dimensional solution structure of NaD1, a new floral defensin from Nicotiana alata and its application to a homology model of the crop defense protein alfAFP
FT Lay, HJ Schirra, MJ Scanlon, MA Anderson, DJ Craik
Journal of molecular biology 325 (1), 175-188, 2003
The cysteine-rich secretory protein domain of Tpx-1 is related to ion channel toxins and regulates ryanodine receptor Ca2+ signaling
GM Gibbs, MJ Scanlon, J Swarbrick, S Curtis, E Gallant, AF Dulhunty, ...
Journal of Biological Chemistry 281 (7), 4156-4163, 2006
Targeting virulence not viability in the search for future antibacterials
B Heras, MJ Scanlon, JL Martin
British journal of clinical pharmacology 79 (2), 208-215, 2015
A Backbone Linker for BOC-Based Peptide Synthesis and On-Resin Cyclization:  Synthesis of Stylostatin 1,
GT Bourne, WDF Meutermans, PF Alewood, RP McGeary, M Scanlon, ...
The Journal of organic chemistry 64 (9), 3095-3101, 1999
Solution structure and proposed binding mechanism of a novel potassium channel toxin κ-conotoxin PVIIA
MJ Scanlon, D Naranjo, L Thomas, PF Alewood, RJ Lewis, DJ Craik
Structure 5 (12), 1585-1597, 1997
Difficult macrocyclizations: new strategies for synthesizing highly strained cyclic tetrapeptides
WDF Meutermans, GT Bourne, SW Golding, DA Horton, MR Campitelli, ...
Organic letters 5 (15), 2711-2714, 2003
Small heat-shock proteins interact with a flanking domain to suppress polyglutamine aggregation
AL Robertson, SJ Headey, HM Saunders, H Ecroyd, MJ Scanlon, ...
Proceedings of the National Academy of Sciences 107 (23), 10424-10429, 2010
Structural and functional analysis of the Josephin domain of the polyglutamine protein ataxin-3
MKM Chow, JP Mackay, JC Whisstock, MJ Scanlon, SP Bottomley
Biochemical and biophysical research communications 322 (2), 387-394, 2004
Characterization of the drug binding specificity of rat liver fatty acid binding protein
S Chuang, T Velkov, J Horne, CJH Porter, MJ Scanlon
Journal of medicinal chemistry 51 (13), 3755-3764, 2008
Neurokinin 1 receptor signaling in endosomes mediates sustained nociception and is a viable therapeutic target for prolonged pain relief
DD Jensen, TM Lieu, ML Halls, NA Veldhuis, WL Imlach, QN Mai, ...
Science translational medicine 9 (392), 2017
Promiscuous 2-aminothiazoles (PrATs): a frequent hitting scaffold
SM Devine, MD Mulcair, CO Debono, EWW Leung, JWM Nissink, SS Lim, ...
Journal of medicinal chemistry 58 (3), 1205-1214, 2015
Parallel screening of low molecular weight fragment libraries: do differences in methodology affect hit identification?
J Wielens, SJ Headey, DI Rhodes, RJ Mulder, O Dolezal, JJ Deadman, ...
Journal of biomolecular screening 18 (2), 147-159, 2013
Solution structure of the cardiostimulant polypeptide anthopleurin-B and comparison with anthopleurin-A
SA Monks, PK Pallaghy, MJ Scanlon, RS Norton
Structure 3 (8), 791-803, 1995
Conformationally constrained macrocycles that mimic tripeptide β-strands in water and aprotic solvents
RC Reid, MJ Kelso, MJ Scanlon, DP Fairlie
Journal of the American Chemical Society 124 (20), 5673-5683, 2002
A novel two-chain proteinase inhibitor generated by circularization of a multidomain precursor protein
MCS Lee, MJ Scanlon, DJ Craik, MA Anderson
Nature structural biology 6 (6), 526-530, 1999
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