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Graham T Holt
Graham T Holt
Graduate Student, Duke University
Verified email at duke.edu
Title
Cited by
Cited by
Year
Sensitive red protein calcium indicators for imaging neural activity
H Dana, B Mohar, Y Sun, S Narayan, A Gordus, JP Hasseman, ...
Elife 5, e12727, 2016
9692016
Axonal Endoplasmic Reticulum Ca2+ Content Controls Release Probability in CNS Nerve Terminals
J de Juan-Sanz, GT Holt, ER Schreiter, F de Juan, DS Kim, TA Ryan
Neuron 93 (4), 867-881. e6, 2017
2442017
Improved methods for marking active neuron populations
B Moeyaert, G Holt, R Madangopal, A Perez-Alvarez, BC Fearey, ...
Nature communications 9 (1), 1-12, 2018
1242018
A low affinity GCaMP3 variant (GCaMPer) for imaging the endoplasmic reticulum calcium store
MJ Henderson, HA Baldwin, CA Werley, S Boccardo, LR Whitaker, X Yan, ...
PLoS One 10 (10), e0139273, 2015
802015
OSPREY 3.0: Open‐source protein redesign for you, with powerful new features
MA Hallen, JW Martin, A Ojewole, JD Jou, AU Lowegard, MS Frenkel, ...
Journal of Computational Chemistry 39 (30), 2494-2507, 2018
692018
Toward Broad Spectrum Dihydrofolate Reductase Inhibitors Targeting Trimethoprim Resistant Enzymes Identified in Clinical Isolates of Methicillin Resistant Staphylococcus aureus
SM Reeve, D Si, J Krucinska, Y Yan, K Viswanathan, S Wang, GT Holt, ...
ACS infectious diseases 5 (11), 1896-1906, 2019
162019
Novel, provable algorithms for efficient ensemble-based computational protein design and their application to the redesign of the c-Raf-RBD: KRas protein-protein interface
AU Lowegard, MS Frenkel, GT Holt, JD Jou, AA Ojewole, BR Donald
PLOS Computational Biology 16 (6), e1007447, 2020
142020
Computational analysis of energy landscapes reveals dynamic features that contribute to binding of inhibitors to CFTR-associated ligand
GT Holt, JD Jou, NP Gill, AU Lowegard, JW Martin, DR Madden, ...
The Journal of Physical Chemistry B 123 (49), 10441-10455, 2019
102019
Chiral evasion and stereospecific antifolate resistance in Staphylococcus aureus
S Wang, SM Reeve, GT Holt, AA Ojewole, MS Frenkel, P Gainza, ...
PLoS computational biology 18 (2), e1009855, 2022
82022
Minimization-Aware Recursive K*: A Novel, Provable Algorithm that Accelerates Ensemble-Based Protein Design and Provably Approximates the Energy Landscape
JD Jou, GT Holt, AU Lowegard, BR Donald
Journal of Computational Biology 27 (4), 550-564, 2020
82020
Minimization-Aware Recursive (): A Novel, Provable Algorithm that Accelerates Ensemble-Based Protein Design and Provably Approximates the Energy …
JD Jou, GT Holt, AU Lowegard, BR Donald
Research in Computational Molecular Biology: 23rd Annual International …, 2019
32019
Improved HIV-1 neutralization breadth and potency of V2-apex antibodies by in silico design
GT Holt, J Gorman, S Wang, AU Lowegard, B Zhang, T Liu, BC Lin, ...
Cell Reports 42 (7), 112711, 2023
22023
Toward Broad Spectrum DHFR inhibitors Targeting Trimethoprim Resistant Enzymes Identified in Clinical Isolates of Methicillin-Resistant Staphylococcus aureus
SM Reeve, D Si, J Krucinska, Y Yan, K Viswanathan, S Wang, GT Holt, ...
ACS infectious diseases 5 (11), 1896, 2019
22019
Improved red protein indicators for in vivo calcium imaging
H Dana, Y Sun, JP Hasseman, G Tsegaye, GT Holt, BF Fosque, ...
Program#/Poster 566, 2014
22014
Ensemble-based Computational Protein Design: Novel Algorithms and Applications to Energy Landscape Approximation, Antibiotic Resistance, and Antibody Design
GT Holt
2022
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Articles 1–15