Juan Carlos Acosta
Juan Carlos Acosta
Edinburgh Cancer Research UK Center, Institute of Genetics and Cancer, University of Edinburgh
Verified email at igmm.ed.ac.uk
Title
Cited by
Cited by
Year
Chemokine signaling via the CXCR2 receptor reinforces senescence
JC Acosta, A O'Loghlen, A Banito, MV Guijarro, A Augert, S Raguz, ...
Cell 133 (6), 1006-1018, 2008
13312008
A complex secretory program orchestrated by the inflammasome controls paracrine senescence
JC Acosta, A Banito, T Wuestefeld, A Georgilis, P Janich, JP Morton, ...
Nature cell biology 15 (8), 978-990, 2013
10192013
Senescence impairs successful reprogramming to pluripotent stem cells
A Banito, ST Rashid, JC Acosta, SD Li, CF Pereira, I Geti, S Pinho, ...
Genes & development 23 (18), 2134-2139, 2009
6002009
mTOR regulates MAPKAPK2 translation to control the senescence-associated secretory phenotype
N Herranz, S Gallage, M Mellone, T Wuestefeld, S Klotz, CJ Hanley, ...
Nature cell biology 17 (9), 1205-1217, 2015
3512015
Histone demethylase JMJD3 contributes to epigenetic control of INK4a/ARF by oncogenic RAS
M Barradas, E Anderton, JC Acosta, SD Li, A Banito, ...
Genes & development 23 (10), 1177-1182, 2009
3312009
Senescence: a new weapon for cancer therapy
JC Acosta, J Gil
Trends in cell biology 22 (4), 211-219, 2012
2092012
p21Cip1 and p27Kip1 induce distinct cell cycle effects and differentiation programs in myeloid leukemia cells
MJ Muñoz-Alonso, JC Acosta, C Richard, MD Delgado, J Sedivy, J León
Journal of Biological Chemistry 280 (18), 18120-18129, 2005
1112005
Control of senescence by CXCR2 and its ligands
JC Acosta, A Loghlen, A Banito, S Raguz, J Gil
Cell cycle 7 (19), 2956-2959, 2008
972008
A role for CXCR2 in senescence, but what about in cancer?
JC Acosta, J Gil
Cancer research 69 (6), 2167-2170, 2009
932009
SKP2 oncogene is a direct MYC target gene and MYC down-regulates p27KIP1 through SKP2 in human leukemia cells
G Bretones, JC Acosta, JM Caraballo, N Ferrándiz, MT Gómez-Casares, ...
Journal of Biological Chemistry 286 (11), 9815-9825, 2011
852011
Myc inhibits p27-induced erythroid differentiation of leukemia cells by repressing erythroid master genes without reversing p27-mediated cell cycle arrest
JC Acosta, N Ferrándiz, G Bretones, V Torrano, R Blanco, C Richard, ...
Molecular and cellular biology 28 (24), 7286-7295, 2008
722008
Inhibition of cell differentiation: a critical mechanism for MYC-mediated carcinogenesis?
J Leon, N Ferrandiz, JC Acosta, MD Delgado
Cell Cycle 8 (8), 1148-1157, 2009
662009
Inhibitory effect of c-Myc on p53-induced apoptosis in leukemia cells. Microarray analysis reveals defective induction of p53 target genes and upregulation of chaperone genes
E Ceballos, MJ Munoz-Alonso, B Berwanger, JC Acosta, R Hernandez, ...
Oncogene 24 (28), 4559-4571, 2005
612005
Suppression of autophagy impedes glioblastoma development and induces senescence
N Gammoh, J Fraser, C Puente, HM Syred, H Kang, T Ozawa, D Lam, ...
Autophagy 12 (9), 1431-1439, 2016
582016
MYC in chronic myeloid leukemia: induction of aberrant DNA synthesis and association with poor response to imatinib
M Albajar, MT Gómez-Casares, J Llorca, I Mauleon, JP Vaqué, JC Acosta, ...
Molecular Cancer Research 9 (5), 564-576, 2011
542011
An adaptive signaling network in melanoma inflammatory niches confers tolerance to MAPK signaling inhibition
HL Young, EJ Rowling, M Bugatti, E Giurisato, N Luheshi, I Arozarena, ...
Journal of Experimental Medicine 214 (6), 1691-1710, 2017
422017
Condensin II mutation causes T-cell lymphoma through tissue-specific genome instability
J Woodward, GC Taylor, DC Soares, S Boyle, D Sie, K Chathoth, ...
Genes & development 30 (19), 2173-2186, 2016
392016
Paracrine cellular senescence exacerbates biliary injury and impairs regeneration
S Ferreira-Gonzalez, WY Lu, A Raven, B Dwyer, TY Man, E O’Duibhir, ...
Nature communications 9 (1), 1-15, 2018
382018
The innate immune sensor Toll-like receptor 2 controls the senescence-associated secretory phenotype
P Hari, FR Millar, N Tarrats, J Birch, A Quintanilla, CJ Rink, ...
Science advances 5 (6), eaaw0254, 2019
352019
Nuclear pore density controls heterochromatin reorganization during senescence
C Boumendil, P Hari, KCF Olsen, JC Acosta, WA Bickmore
Genes & development 33 (3-4), 144-149, 2019
322019
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