Alexander Swarbrick
Alexander Swarbrick
Laboratory Head, Garvan Institute of Medical Research | Co-Head, Breast Translational Oncology
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miR-380-5p represses p53 to control cellular survival and is associated with poor outcome in MYCN-amplified neuroblastoma
A Swarbrick, SL Woods, A Shaw, A Balakrishnan, Y Phua, A Nguyen, ...
Nature medicine 16 (10), 1134-1140, 2010
Tyrosine phosphorylation profiling reveals the signaling network characteristics of Basal breast cancer cells
F Hochgräfe, L Zhang, SA O'Toole, BC Browne, M Pinese, AP Cubas, ...
Cancer research 70 (22), 9391-9401, 2010
Mechanisms of cyclin-dependent kinase inactivation by progestins
EA Musgrove, A Swarbrick, CSL Lee, AL Cornish, RL Sutherland
Molecular and cellular biology 18 (4), 1812-1825, 1998
Hedgehog overexpression is associated with stromal interactions and predicts for poor outcome in breast cancer
SA O'Toole, DA Machalek, RF Shearer, EKA Millar, R Nair, P Schofield, ...
Cancer research 71 (11), 4002-4014, 2011
Therapeutic targets in triple negative breast cancer
SA O'Toole, JM Beith, EKA Millar, R West, A McLean, A Cazet, ...
Journal of clinical pathology 66 (6), 530-542, 2013
Programmed death ligand 1 expression in triple‐negative breast cancer is associated with tumour‐infiltrating lymphocytes and improved outcome
RK Beckers, CI Selinger, R Vilain, J Madore, JS Wilmott, K Harvey, ...
Histopathology 69 (1), 25-34, 2016
Id1 cooperates with oncogenic Ras to induce metastatic mammary carcinoma by subversion of the cellular senescence response
A Swarbrick, E Roy, T Allen, JM Bishop
Proceedings of the National Academy of Sciences 105 (14), 5402-5407, 2008
MicroRNAs regulate tumor angiogenesis modulated by endothelial progenitor cells
PN Plummer, R Freeman, RJ Taft, J Vider, M Sax, BA Umer, D Gao, ...
Cancer research 73 (1), 341-352, 2013
Mechanisms of growth arrest by c-myc antisense oligonucleotides in MCF-7 breast cancer cells: implications for the antiproliferative effects of antiestrogens
JS Carroll, A Swarbrick, EA Musgrove, RL Sutherland
Cancer Research 62 (11), 3126-3131, 2002
Circulating microRNAs are associated with docetaxel chemotherapy outcome in castration-resistant prostate cancer
HM Lin, L Castillo, KL Mahon, K Chiam, BY Lee, Q Nguyen, MJ Boyer, ...
British journal of cancer 110 (10), 2462-2471, 2014
Antiprogestin inhibition of cell cycle progression in T-47D breast cancer cells is accompanied by induction of the cyclin-dependent kinase inhibitor p21
EA Musgrove, CSL Lee, AL Cornish, A Swarbrick, RL Sutherland
Molecular endocrinology 11 (1), 54-66, 1997
Regulation of cyclin expression and cell cycle progression in breast epithelial cells by the helix–loop–helix protein Id1
A Swarbrick, MC Åkerfeldt, CSL Lee, CM Sergio, CE Caldon, LJK Hunter, ...
Oncogene 24 (3), 381-389, 2005
Targeting stromal remodeling and cancer stem cell plasticity overcomes chemoresistance in triple negative breast cancer
AS Cazet, MN Hui, BL Elsworth, SZ Wu, D Roden, CL Chan, JN Skhinas, ...
Nature communications 9 (1), 1-18, 2018
Real-time intravital imaging establishes tumor-associated macrophages as the extraskeletal target of bisphosphonate action in cancer
S Junankar, G Shay, J Jurczyluk, N Ali, J Down, N Pocock, A Parker, ...
Cancer discovery 5 (1), 35-42, 2015
c-Myc and Her2 cooperate to drive a stem-like phenotype with poor prognosis in breast cancer
R Nair, DL Roden, WS Teo, A McFarland, S Junankar, S Ye, A Nguyen, ...
Oncogene 33 (30), 3992-4002, 2014
Effects of a novel long noncoding RNA, lncUSMycN, on N-Myc expression and neuroblastoma progression
PY Liu, D Erriquez, GM Marshall, AE Tee, P Polly, M Wong, B Liu, JL Bell, ...
JNCI: Journal of the National Cancer Institute 106 (7), dju113, 2014
The Hedgehog signalling pathway in breast development, carcinogenesis and cancer therapy
M Hui, A Cazet, R Nair, DN Watkins, SA O'Toole, A Swarbrick
Breast Cancer Research 15 (2), 1-14, 2013
Using the transcription factor inhibitor of DNA binding 1 to selectively target endothelial progenitor cells offers novel strategies to inhibit tumor angiogenesis and growth
AS Mellick, PN Plummer, DJ Nolan, D Gao, K Bambino, M Hahn, ...
Cancer research 70 (18), 7273-7282, 2010
Cooperation of p27Kip1 and p18INK4c in progestin-mediated cell cycle arrest in T-47D breast cancer cells
A Swarbrick, CSL Lee, RL Sutherland, EA Musgrove
Molecular and Cellular Biology 20 (7), 2581-2591, 2000
Lack of relationship between CDK activity and G 1 cyclin expression in breast cancer cells
KJ Sweeney, A Swarbrick, RL Sutherland, EA Musgrove
Oncogene 16 (22), 2865-2878, 1998
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