Fung T Lay
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Defensins-components of the innate immune system in plants
FT Lay, MA Anderson
Current Protein and Peptide Science 6 (1), 85-101, 2005
Isolation and properties of floral defensins from ornamental tobacco and petunia
FT Lay, F Brugliera, MA Anderson
Plant physiology 131 (3), 1283-1293, 2003
The plant defensin, NaD1, enters the cytoplasm of Fusarium oxysporum hyphae
NL Van Der Weerden, FT Lay, MA Anderson
Journal of Biological Chemistry 283 (21), 14445-14452, 2008
The three-dimensional solution structure of NaD1, a new floral defensin from Nicotiana alata and its application to a homology model of the crop defense protein alfAFP
FT Lay, HJ Schirra, MJ Scanlon, MA Anderson, DJ Craik
Journal of molecular biology 325 (1), 175-188, 2003
Coexpression of potato type I and II proteinase inhibitors gives cotton plants protection against insect damage in the field
KM Dunse, JA Stevens, FT Lay, YM Gaspar, RL Heath, MA Anderson
Proceedings of the National Academy of Sciences 107 (34), 15011-15015, 2010
Phosphoinositide-mediated oligomerization of a defensin induces cell lysis
IKH Poon, AA Baxter, FT Lay, GD Mills, CG Adda, JAE Payne, TK Phan, ...
Elife 3, e01808, 2014
Structure of Petunia hybrida defensin 1, a novel plant defensin with five disulfide bonds
BJC Janssen, HJ Schirra, FT Lay, MA Anderson, DJ Craik
Biochemistry 42 (27), 8214-8222, 2003
A pollen-specific RALF from tomato that regulates pollen tube elongation
PA Covey, CC Subbaiah, RL Parsons, G Pearce, FT Lay, MA Anderson, ...
Plant physiology 153 (2), 703-715, 2010
Novel insights on the mechanism of action of α‐amylase inhibitors from the plant defensin family
PB Pelegrini, FT Lay, AM Murad, MA Anderson, OL Franco
Proteins: Structure, Function, and Bioinformatics 73 (3), 719-729, 2008
Convergent evolution of defensin sequence, structure and function
TMA Shafee, FT Lay, TK Phan, MA Anderson, MD Hulett
Cellular and Molecular Life Sciences 74 (4), 663-682, 2017
The defensins consist of two independent, convergent protein superfamilies
TMA Shafee, FT Lay, MD Hulett, MA Anderson
Molecular biology and evolution 33 (9), 2345-2356, 2016
Dimerization of plant defensin NaD1 enhances its antifungal activity
FT Lay, GD Mills, IKH Poon, NP Cowieson, N Kirby, AA Baxter, ...
Journal of Biological Chemistry 287 (24), 19961-19972, 2012
The tomato defensin TPP3 binds phosphatidylinositol (4, 5)-bisphosphate via a conserved dimeric cationic grip conformation to mediate cell lysis
AA Baxter, V Richter, FT Lay, IKH Poon, CG Adda, PK Veneer, TK Phan, ...
Molecular and cellular biology 35 (11), 1964-1978, 2015
Tumor cell membrane-targeting cationic antimicrobial peptides: novel insights into mechanisms of action and therapeutic prospects
AA Baxter, FT Lay, IKH Poon, M Kvansakul, MD Hulett
Cellular and Molecular Life Sciences 74 (20), 3809-3825, 2017
X-ray structure of a carpet-like antimicrobial defensin–phospholipid membrane disruption complex
M Järvå, FT Lay, TK Phan, C Humble, IKH Poon, MR Bleackley, ...
Nature communications 9 (1), 1-10, 2018
The C-terminal propeptide of a plant defensin confers cytoprotective and subcellular targeting functions
FT Lay, S Poon, JA McKenna, AA Connelly, BL Barbeta, BS McGinness, ...
BMC plant biology 14 (1), 1-13, 2014
Binding of phosphatidic acid by NsD7 mediates the formation of helical defensin–lipid oligomeric assemblies and membrane permeabilization
M Kvansakul, FT Lay, CG Adda, PK Veneer, AA Baxter, TK Phan, ...
Proceedings of the National Academy of Sciences 113 (40), 11202-11207, 2016
Human β-defensin 3 contains an oncolytic motif that binds PI (4, 5) P2 to mediate tumour cell permeabilisation
TK Phan, FT Lay, IKH Poon, MG Hinds, M Kvansakul, MD Hulett
Oncotarget 7 (2), 2054, 2016
Host defense peptides: roles and applications
A Tossi
Curr Protein Pept Sci 6 (1), 1-3, 2005
Defensin-encoding nucleic acid molecules derived from nicotiana alata, uses therfor and transgenic plants comprising same
MA Anderson, FT Lay, RL Heath
US Patent 7,041,877, 2006
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