Dene Littler
Dene Littler
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The intracellular chloride ion channel protein CLIC1 undergoes a redox-controlled structural transition
DR Littler, SJ Harrop, WD Fairlie, LJ Brown, GJ Pankhurst, S Pankhurst, ...
Journal of Biological Chemistry 279 (10), 9298-9305, 2004
The enigma of the CLIC proteins: Ion channels, redox proteins, enzymes, scaffolding proteins?
DR Littler, SJ Harrop, SC Goodchild, JM Phang, AV Mynott, L Jiang, ...
FEBS letters 584 (10), 2093-2101, 2010
Crystal structure of the SARS-CoV-2 non-structural protein 9, Nsp9
DR Littler, BS Gully, RN Colson, J Rossjohn
Iscience 23 (7), 2020
Structure of the FoxM1 DNA-recognition domain bound to a promoter sequence
DR Littler, M Alvarez-Fernandez, A Stein, RG Hibbert, T Heidebrecht, ...
Nucleic acids research 38 (13), 4527-4538, 2010
A TPR domain–containing N-terminal module of MPS1 is required for its kinetochore localization by Aurora B
W Nijenhuis, E Von Castelmur, D Littler, V De Marco, E Tromer, M Vleugel, ...
Journal of Cell Biology 201 (2), 217-231, 2013
Crystal structure of the soluble form of the redox‐regulated chloride ion channel protein CLIC4
DR Littler, NN Assaad, SJ Harrop, LJ Brown, GJ Pankhurst, P Luciani, ...
The FEBS journal 272 (19), 4996-5007, 2005
In vivo protein cyclization promoted by a circularly permuted Synechocystis sp. PCC6803 DnaB mini-intein
NK Williams, P Prosselkov, E Liepinsh, I Line, A Sharipo, DR Littler, ...
Journal of Biological Chemistry 277 (10), 7790-7798, 2002
Enabling high-throughput ligation-independent cloning and protein expression for the family of ubiquitin specific proteases
MPA Luna-Vargas, E Christodoulou, A Alfieri, WJ van Dijk, M Stadnik, ...
Journal of structural biology 175 (2), 113-119, 2011
Oxidation promotes insertion of the CLIC1 chloride intracellular channel into the membrane
SC Goodchild, MW Howell, NM Cordina, DR Littler, SN Breit, PMG Curmi, ...
European biophysics journal 39, 129-138, 2009
Molecular basis of cytokine receptor activation
AF Lopez, TR Hercus, P Ekert, DR Littler, M Guthridge, D Thomas, ...
IUBMB life 62 (7), 509-518, 2010
Structure of the Janus protein human CLIC2
BA Cromer, MA Gorman, G Hansen, JJ Adams, M Coggan, DR Littler, ...
Journal of molecular biology 374 (3), 719-731, 2007
Comparison of vertebrate and invertebrate CLIC proteins: The crystal structures of Caenorhabditis elegans EXC‐4 and Drosophila melanogaster DmCLIC
DR Littler, SJ Harrop, LJ Brown, GJ Pankhurst, AV Mynott, P Luciani, ...
Proteins: Structure, Function, and Bioinformatics 71 (1), 364-378, 2008
Polo-box domains confer target specificity to the Polo-like kinase family
BCM van de Weerdt, DR Littler, R Klompmaker, A Huseinovic, A Fish, ...
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1783 (6), 1015-1022, 2008
Spatiotemporal regulation of chloride intracellular channel protein CLIC4 by RhoA
B Ponsioen, L van Zeijl, M Langeslag, M Berryman, D Littler, K Jalink, ...
Molecular biology of the cell 20 (22), 4664-4672, 2009
Metamorphic response of the CLIC1 chloride intracellular ion channel protein upon membrane interaction
SC Goodchild, MW Howell, DR Littler, RA Mandyam, KL Sale, M Mazzanti, ...
Biochemistry 49 (25), 5278-5289, 2010
A conserved mechanism of autoinhibition for the AMPK kinase domain: ATP-binding site and catalytic loop refolding as a means of regulation
DR Littler, JR Walker, T Davis, LE Wybenga-Groot, PJ Finerty, E Newman, ...
Acta Crystallographica Section F: Structural Biology and Crystallization…, 2010
Structure of human CLIC3 at 2 resolution
DR Littler, LJ Brown, SN Breit, A Perrakis, PMG Curmi
Proteins: Structure, Function, and Bioinformatics 78 (6), 1594-1600, 2010
The structural basis for recognition of base J containing DNA by a novel DNA binding domain in JBP1
T Heidebrecht, E Christodoulou, MJ Chalmers, S Jan, B Ter Riet, ...
Nucleic acids research 39 (13), 5715-5728, 2011
A natural product compound inhibits coronaviral replication in vitro by binding to the conserved Nsp9 SARS-CoV-2 protein
DR Littler, M Liu, JL McAuley, SA Lowery, PT Illing, BS Gully, AW Purcell, ...
Journal of Biological Chemistry 297 (6), 2021
Structure of human protein kinase C eta (PKCη) C2 domain and identification of phosphorylation sites
DR Littler, JR Walker, YM She, PJ Finerty Jr, EM Newman, ...
Biochemical and biophysical research communications 349 (4), 1182-1189, 2006
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