Recurring mutations found by sequencing an acute myeloid leukemia genome ER Mardis, L Ding, DJ Dooling, DE Larson, MD McLellan, K Chen, ... New England Journal of Medicine 361 (11), 1058-1066, 2009 | 2655 | 2009 |
BreakDancer: an algorithm for high-resolution mapping of genomic structural variation K Chen, JW Wallis, MD McLellan, DE Larson, JM Kalicki, CS Pohl, ... Nature methods 6 (9), 677-681, 2009 | 1620 | 2009 |
DNA sequencing of a cytogenetically normal acute myeloid leukaemia genome TJ Ley, ER Mardis, L Ding, B Fulton, MD McLellan, K Chen, D Dooling, ... Nature 456 (7218), 66-72, 2008 | 1570 | 2008 |
Genome remodelling in a basal-like breast cancer metastasis and xenograft LI Ding, MJ Ellis, S Li, DE Larson, K Chen, JW Wallis, CC Harris, ... Nature 464 (7291), 999-1005, 2010 | 1349 | 2010 |
Segmental duplications and copy-number variation in the human genome AJ Sharp, DP Locke, SD McGrath, Z Cheng, JA Bailey, RU Vallente, ... The American Journal of Human Genetics 77 (1), 78-88, 2005 | 1190 | 2005 |
Genome analysis of the platypus reveals unique signatures of evolution Nature 453 (7192), 175-183, 2008 | 768 | 2008 |
Comparative and demographic analysis of orang-utan genomes DP Locke, LDW Hillier, WC Warren, KC Worley, LV Nazareth, DM Muzny, ... Nature 469 (7331), 529-533, 2011 | 686 | 2011 |
Chimpanzee and human Y chromosomes are remarkably divergent in structure and gene content JF Hughes, H Skaletsky, T Pyntikova, TA Graves, SKM Van Daalen, ... Nature 463 (7280), 536-539, 2010 | 457 | 2010 |
Linkage disequilibrium and heritability of copy-number polymorphisms within duplicated regions of the human genome DP Locke, AJ Sharp, SA McCarroll, SD McGrath, TL Newman, Z Cheng, ... The American journal of human genetics 79 (2), 275-290, 2006 | 400 | 2006 |
Gibbon genome and the fast karyotype evolution of small apes L Carbone, R Alan Harris, S Gnerre, KR Veeramah, B Lorente-Galdos, ... Nature 513 (7517), 195-201, 2014 | 355 | 2014 |
Identification of four highly conserved genes between breakpoint hotspots BP1 and BP2 of the Prader-Willi/Angelman syndromes deletion region that have undergone evolutionary … JH Chai, DP Locke, JM Greally, JHM Knoll, T Ohta, J Dunai, A Yavor, ... The American Journal of Human Genetics 73 (4), 898-925, 2003 | 258 | 2003 |
The common marmoset genome provides insight into primate biology and evolution TMG Sequencing, Analysis Consortium Nature genetics 46 (8), 850, 2014 | 203 | 2014 |
Large-scale variation among human and great ape genomes determined by array comparative genomic hybridization DP Locke, R Segraves, L Carbone, N Archidiacono, DG Albertson, ... Genome research 13 (3), 347-357, 2003 | 184 | 2003 |
Avian W and mammalian Y chromosomes convergently retained dosage-sensitive regulators DW Bellott, H Skaletsky, TJ Cho, L Brown, D Locke, N Chen, S Galkina, ... Nature genetics 49 (3), 387-394, 2017 | 165 | 2017 |
Lessons from the human genome: transitions between euchromatin and heterochromatin JE Horvath, JA Bailey, DP Locke, EE Eichler Human Molecular Genetics 10 (20), 2215-2223, 2001 | 161 | 2001 |
A continuum of admixture in the Western Hemisphere revealed by the African Diaspora genome RA Mathias, MA Taub, CR Gignoux, W Fu, S Musharoff, TD O'Connor, ... Nature communications 7 (1), 12522, 2016 | 156 | 2016 |
Refinement of a chimpanzee pericentric inversion breakpoint to a segmental duplication cluster DP Locke, N Archidiacono, D Misceo, MF Cardone, S Deschamps, B Roe, ... Genome Biology 4, 1-9, 2003 | 149 | 2003 |
BAC microarray analysis of 15q11–q13 rearrangements and the impact of segmental duplications DP Locke, R Segraves, RD Nicholls, S Schwartz, D Pinkel, DG Albertson, ... Journal of medical genetics 41 (3), 175-182, 2004 | 125 | 2004 |
Phylogenetic relationships among highly virulent Newcastle disease virus isolates obtained from exotic birds and poultry from 1989 to 1996 BS Seal, DJ King, DP Locke, DA Senne, MW Jackwood Journal of clinical Microbiology 36 (4), 1141-1145, 1998 | 113 | 1998 |
Analysis of the DNA sequence and duplication history of human chromosome 15 MC Zody, M Garber, T Sharpe, SK Young, L Rowen, K O'Neill, ... Nature 440 (7084), 671-675, 2006 | 89 | 2006 |