| NOTCH blockade combined with radiation therapy and temozolomide prolongs survival of orthotopic glioblastoma S Yahyanejad, H King, VS Iglesias, PV Granton, LMO Barbeau, ... Oncotarget 7 (27), 41251, 2016 | 89 | 2016 |
| Regulated proteolysis of NOTCH2 and NOTCH3 receptors by ADAM10 and presenilins AJ Groot, R Habets, S Yahyanejad, CM Hodin, K Reiss, P Saftig, J Theys, ... Molecular and cellular biology 34 (15), 2822-2832, 2014 | 88 | 2014 |
| High NOTCH activity induces radiation resistance in non small cell lung cancer J Theys, S Yahyanejad, R Habets, P Span, L Dubois, K Paesmans, ... Radiotherapy and oncology 108 (3), 440-445, 2013 | 71 | 2013 |
| Targeting Notch to overcome radiation resistance S Yahyanejad, J Theys, M Vooijs Oncotarget 7 (7), 7610, 2016 | 64 | 2016 |
| The anti-malarial drug chloroquine sensitizes oncogenic NOTCH1 driven human T-ALL to γ-secretase inhibition J Hounjet, R Habets, MB Schaaf, TC Hendrickx, LMO Barbeau, ... Oncogene 38 (27), 5457-5468, 2019 | 29 | 2019 |
| An image guided small animal radiation therapy platform (SmART) to monitor glioblastoma progression and therapy response S Yahyanejad, SJ van Hoof, J Theys, LMO Barbeau, PV Granton, ... Radiotherapy and Oncology 116 (3), 467-472, 2015 | 29 | 2015 |
| Human NOTCH2 is resistant to ligand-independent activation by metalloprotease Adam17 RAJ Habets, AJ Groot, S Yahyanejad, K Tiyanont, SC Blacklow, M Vooijs Journal of biological chemistry 290 (23), 14705-14716, 2015 | 29 | 2015 |
| Complementary use of bioluminescence imaging and contrast-enhanced micro—computed tomography in an orthotopic brain tumor model S Yahyanejad, PV Granton, NG Lieuwes, L Gilmour, L Dubois, J Theys, ... Molecular Imaging 13 (4), 7290.2014. 00038, 2014 | 29 | 2014 |
| Multi-modal effects of 1B3, a novel synthetic miR-193a-3p mimic, support strong potential for therapeutic intervention in oncology BJ Telford, S Yahyanejad, T de Gunst, HC den Boer, RM Vos, M Stegink, ... Oncotarget 12 (5), 422, 2021 | 16 | 2021 |
| Transcriptome-wide analysis reveals insight into tumor suppressor functions of 1B3, a novel synthetic miR-193a-3p mimic MTJ van den Bosch, S Yahyanejad, MF Alemdehy, BJ Telford, T de Gunst, ... Molecular Therapy-Nucleic Acids 23, 1161-1171, 2021 | 8 | 2021 |
| Phase I/Ib study with INT-1B3, a novel LNP-formulated micro-RNA (miR-193a-3p mimic) therapeutic for patients with advanced solid cancer. N Kotecki, F Opdam, D Robbrecht, M Strijbos, K Kroon, M Janicot, ... Journal of Clinical Oncology 39 (15_suppl), TPS2666-TPS2666, 2021 | 6 | 2021 |
| Pharmacologic profile of INT-1B3: A novel synthetic microRNA 193a-3p mimic for therapeutic intervention in oncology S Yahyanejad, T Gunst, I Schultz, H Boer, M Raimo, B Telford, R Vos, ... Cancer Research 78 (13_Supplement), 4405-4405, 2018 | 5 | 2018 |
| Anticancer microRNA and lipid formulations thereof MM De Gunst, LAH Van Pinxteren, M Janicot, IJ Schultz, RQJ Schaapveld, ... US Patent App. 16/966,869, 2021 | 2 | 2021 |
| SmART-ER imaging and treatment of glioblastoma PV Granton, S Yahyanejad, MA Vooijs Journal of Neuro-Oncology 123, 319-320, 2015 | 2 | 2015 |
| EP-1350: Malignant mucosal melanoma in the upper aerodigestive tract treated with carbon ion RT at CNAO: preliminary results V Vitolo, P Fossati, M Bonora, A Iannalfi, MR Fiore, V Vischioni, E Ciurlia, ... Radiotherapy and Oncology 115, S728, 2015 | 2 | 2015 |
| P422: TARGETING THE WT1MUT-MIR-193A TRANSCRIPTIONAL AXIS WITH INT-1B3, A NOVEL LIPID NANOPARTICLE-FORMULATED MIR-193A-3P MIMIC IN ACUTE MYELOID LEUKEMIA X Yang, K Krowiorz, D Buelow, R Bhayadia, J Kohlschmidt, D Nicolet, ... HemaSphere 7 (S3), e43178c6, 2023 | | 2023 |
| The tumor suppressor 5A2, a synthetic miR-7-5p mimic, targets oncogenic and metabolic pathways, as revealed by transcriptome-wide analysis MTJ van den Bosch, BJ Telford, S Yahyanejad, T de Gunst, HC den Boer, ... Frontiers in Drug Discovery 3, 1181637, 2023 | | 2023 |
| miRNA-193a for Promoting Immunogenic Cell Death S Yahyanejad, B Telford, M VAN DEN BOSCH, MF Alemdehy, ... US Patent App. 17/904,864, 2023 | | 2023 |
| Targeting the WT1mut-Mir-193a Transcriptional Axis with INT-1B3, a Novel Lipid Nanoparticle-Formulated Mir-193a-3p Mimic in Acute Myeloid Leukemia X Yang, K Krowiorz, R Bhayadia, J Kohlschmidt, D Nicolet, T Maetzig, ... Blood 140 (Supplement 1), 6224-6225, 2022 | | 2022 |
| New treatments involving mirna-193a S Yahyanejad, BJ Telford, MTJ VAN DEN BOSCH, MF Alemdehy, ... US Patent App. 17/630,457, 2022 | | 2022 |
