| Mechanism linking T-wave alternans to the genesis of cardiac fibrillation JM Pastore, SD Girouard, KR Laurita, FG Akar, DS Rosenbaum Circulation 99 (10), 1385-1394, 1999 | 1037 | 1999 |
| Functional integration of electrically active cardiac derivatives from genetically engineered human embryonic stem cells with quiescent recipient ventricular cardiomyocytes … T Xue, HC Cho, FG Akar, SY Tsang, SP Jones, E Marbán, GF Tomaselli, ... Circulation 111 (1), 11-20, 2005 | 632 | 2005 |
| Oxidative stress and inflammation as central mediators of atrial fibrillation in obesity and diabetes BS Karam, A Chavez-Moreno, W Koh, JG Akar, FG Akar Cardiovascular diabetology 16, 1-9, 2017 | 407 | 2017 |
| The mitochondrial origin of postischemic arrhythmias FG Akar, MA Aon, GF Tomaselli, B O’Rourke The Journal of clinical investigation 115 (12), 3527-3535, 2005 | 406 | 2005 |
| Mechanisms underlying conduction slowing and arrhythmogenesis in nonischemic dilated cardiomyopathy FG Akar, DD Spragg, RS Tunin, DA Kass, GF Tomaselli Circulation research 95 (7), 717-725, 2004 | 405 | 2004 |
| Transmural electrophysiological heterogeneities underlying arrhythmogenesis in heart failure FG Akar, DS Rosenbaum Circulation research 93 (7), 638-645, 2003 | 388 | 2003 |
| Unique topographical distribution of M cells underlies reentrant mechanism of torsade de pointes in the long-QT syndrome FG Akar, GX Yan, C Antzelevitch, DS Rosenbaum Circulation 105 (10), 1247-1253, 2002 | 383 | 2002 |
| Dynamic changes in conduction velocity and gap junction properties during development of pacing-induced heart failure FG Akar, RD Nass, S Hahn, E Cingolani, M Shah, GG Hesketh, ... American Journal of Physiology-Heart and Circulatory Physiology, 2007 | 233 | 2007 |
| Electrophysiological consequences of dyssynchronous heart failure and its restoration by resynchronization therapy T Aiba, GG Hesketh, AS Barth, T Liu, S Daya, K Chakir, VL Dimaano, ... Circulation 119 (9), 1220-1230, 2009 | 231 | 2009 |
| Molecular basis of arrhythmias M Shah, FG Akar, GF Tomaselli Circulation 112 (16), 2517-2529, 2005 | 231 | 2005 |
| Heterogeneous connexin43 expression produces electrophysiological heterogeneities across ventricular wall S Poelzing, FG Akar, E Baron, DS Rosenbaum American Journal of Physiology-Heart and Circulatory Physiology 286 (5 …, 2004 | 203 | 2004 |
| Bioartificial sinus node constructed via in vivo gene transfer of an engineered pacemaker HCN Channel reduces the dependence on electronic pacemaker in a sick-sinus syndrome model HF Tse, T Xue, CP Lau, CW Siu, K Wang, QY Zhang, GF Tomaselli, ... Circulation 114 (10), 1000-1011, 2006 | 193 | 2006 |
| Advancing functional engineered cardiac tissues toward a preclinical model of human myocardium IC Turnbull, I Karakikes, GW Serrao, P Backeris, JJ Lee, C Xie, G Senyei, ... The FASEB Journal 28 (2), 644, 2014 | 180 | 2014 |
| Abnormal conduction and repolarization in late-activated myocardium of dyssynchronously contracting hearts DD Spragg, FG Akar, RH Helm, RS Tunin, GF Tomaselli, DA Kass Cardiovascular research 67 (1), 77-86, 2005 | 175 | 2005 |
| Ultrastructure and regulation of lateralized connexin43 in the failing heart GG Hesketh, MH Shah, VL Halperin, CA Cooke, FG Akar, TE Yen, ... Circulation research 106 (6), 1153-1163, 2010 | 174 | 2010 |
| Mitochondrial criticality: a new concept at the turning point of life or death MA Aon, S Cortassa, FG Akar, B O'Rourke Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1762 (2), 232-240, 2006 | 162 | 2006 |
| Modulated dispersion explains changes in arrhythmia vulnerability during premature stimulation of the heart KR Laurita, SD Girouard, FG Akar, DS Rosenbaum Circulation 98 (24), 2774-2780, 1998 | 144 | 1998 |
| Na+ channel regulation by Ca2+/calmodulin and Ca2+/calmodulin-dependent protein kinase II in guinea-pig ventricular myocytes T Aiba, GG Hesketh, T Liu, R Carlisle, MC Villa-Abrille, B O'Rourke, ... Cardiovascular research 85 (3), 454-463, 2010 | 135 | 2010 |
| Mechanisms of disease: ion channel remodeling in the failing ventricle RD Nass, T Aiba, GF Tomaselli, FG Akar Nature Clinical Practice Cardiovascular Medicine 5 (4), 196-207, 2008 | 134 | 2008 |
| From mitochondrial dynamics to arrhythmias MA Aon, S Cortassa, FG Akar, DA Brown, L Zhou, B O’rourke The international journal of biochemistry & cell biology 41 (10), 1940-1948, 2009 | 133 | 2009 |
Brian O'RourkeJohns Hopkins UniversityVerified email at jhmi.edu
