Crystal structure of a complex between the catalytic and regulatory (RIα) subunits of PKA C Kim, NH Xuong, SS Taylor Science 307 (5710), 690-696, 2005 | 419 | 2005 |
PKA-I holoenzyme structure reveals a mechanism for cAMP-dependent activation C Kim, CY Cheng, SA Saldanha, SS Taylor Cell 130 (6), 1032-1043, 2007 | 405 | 2007 |
Dynamics of signaling by PKA SS Taylor, C Kim, D Vigil, NM Haste, J Yang, J Wu, GS Anand Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1754 (1-2), 25-37, 2005 | 316 | 2005 |
The genetic basis of DOORS syndrome: an exome-sequencing study PM Campeau, D Kasperaviciute, JT Lu, LC Burrage, C Kim, M Hori, ... The Lancet Neurology 13 (1), 44-58, 2014 | 279 | 2014 |
Signaling through cAMP and cAMP-dependent protein kinase: diverse strategies for drug design SS Taylor, C Kim, CY Cheng, SHJ Brown, J Wu, N Kannan Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1784 (1), 16-26, 2008 | 263 | 2008 |
A dynamic mechanism for AKAP binding to RII isoforms of cAMP-dependent protein kinase FS Kinderman, C Kim, S von Daake, Y Ma, BQ Pham, G Spraggon, ... Molecular cell 24 (3), 397-408, 2006 | 243 | 2006 |
Recurrent gain-of-function mutation in PRKG1 causes thoracic aortic aneurysms and acute aortic dissections D Guo, E Regalado, DE Casteel, RL Santos-Cortez, L Gong, JJ Kim, ... The American Journal of Human Genetics 93 (2), 398-404, 2013 | 228 | 2013 |
The structures of anthranilate synthase of Serratia marcescens crystallized in the presence of (i) its substrates, chorismate and glutamine, and a product, glutamate, and (ii … G Spraggon, C Kim, X Nguyen-Huu, MC Yee, C Yanofsky, SE Mills Proceedings of the National Academy of Sciences 98 (11), 6021-6026, 2001 | 154 | 2001 |
Structure of D-AKAP2: PKA RI complex: insights into AKAP specificity and selectivity GN Sarma, FS Kinderman, C Kim, S von Daake, L Chen, BC Wang, ... Structure 18 (2), 155-166, 2010 | 132 | 2010 |
Generation of candidate ligands for nicotinic acetylcholine receptors via in situ click chemistry with a soluble acetylcholine binding protein template NP Grimster, B Stump, JR Fotsing, T Weide, TT Talley, JG Yamauchi, ... Journal of the American Chemical Society 134 (15), 6732-6740, 2012 | 94 | 2012 |
Structure and dynamics of PKA signaling proteins. C Kim, D Vigil, G Anand, SS Taylor European journal of cell biology 85 (7), 651-654, 2006 | 93 | 2006 |
Prevention of PKG1α oxidation augments cardioprotection in the stressed heart T Nakamura, MJ Ranek, DI Lee, VS Hahn, C Kim, P Eaton, DA Kass The Journal of clinical investigation 125 (6), 2468-2472, 2015 | 77 | 2015 |
Cyclic AMP analog blocks kinase activation by stabilizing inactive conformation: conformational selection highlights a new concept in allosteric inhibitor design S Badireddy, G Yunfeng, M Ritchie, P Akamine, J Wu, CW Kim, SS Taylor, ... Molecular & Cellular Proteomics 10 (3), 2011 | 76 | 2011 |
Structural basis for cyclic-nucleotide selectivity and cGMP-selective activation of PKG I GY Huang, JJ Kim, AS Reger, R Lorenz, EW Moon, C Zhao, DE Casteel, ... Structure 22 (1), 116-124, 2014 | 75 | 2014 |
Co-crystal structures of PKG Iβ (92–227) with cGMP and cAMP reveal the molecular details of cyclic-nucleotide binding JJ Kim, DE Casteel, G Huang, TH Kwon, RK Ren, P Zwart, JJ Headd, ... PloS one 6 (4), e18413, 2011 | 75 | 2011 |
DIRAS3 regulates the autophagosome initiation complex in dormant ovarian cancer cells Z Lu, MT Baquero, H Yang, M Yang, AS Reger, C Kim, DA Levine, ... Autophagy 10 (6), 1071-1092, 2014 | 69 | 2014 |
p75 neurotrophin receptor regulates glucose homeostasis and insulin sensitivity B Baeza-Raja, P Li, N Le Moan, BD Sachs, C Schachtrup, D Davalos, ... Proceedings of the National Academy of Sciences 109 (15), 5838-5843, 2012 | 61 | 2012 |
Comparative surface geometry of the protein kinase family EE Thompson, AP Kornev, N Kannan, C Kim, LF Ten Eyck, SS Taylor Protein science 18 (10), 2016-2026, 2009 | 59 | 2009 |
Liquid condensation of reprogramming factor KLF4 with DNA provides a mechanism for chromatin organization R Sharma, KJ Choi, MD Quan, S Sharma, B Sankaran, H Park, A LaGrone, ... Nature communications 12 (1), 5579, 2021 | 53 | 2021 |
Realizing the allosteric potential of the tetrameric protein kinase A RIα holoenzyme AJ Boettcher, J Wu, C Kim, J Yang, J Bruystens, N Cheung, ... Structure 19 (2), 265-276, 2011 | 52 | 2011 |