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Chuan Chen
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Efficient bacterial inactivation by transition metal catalyzed auto-oxidation of sulfite
L Chen, M Tang, C Chen, M Chen, K Luo, J Xu, D Zhou, F Wu
Environmental Science & Technology 51 (21), 12663-12671, 2017
1312017
High potency of a bivalent human VH domain in SARS-CoV-2 animal models
W Li, A Schäfer, SS Kulkarni, X Liu, DR Martinez, C Chen, Z Sun, SR Leist, ...
Cell 183 (2), 429-441. e16, 2020
1222020
Rapid identification of a human antibody with high prophylactic and therapeutic efficacy in three animal models of SARS-CoV-2 infection
W Li, C Chen, A Drelich, DR Martinez, LE Gralinski, Z Sun, A Schäfer, ...
Proceedings of the National Academy of Sciences 117 (47), 29832-29838, 2020
882020
Critical role of matrix metalloproteinase 14 in adipose tissue remodeling during obesity
X Li, Y Zhao, C Chen, L Yang, H Lee, Z Wang, N Zhang, MG Kolonin, Z An, ...
Molecular and cellular biology 40 (8), e00564-19, 2020
702020
Non-lytic M13 phage-based highly sensitive impedimetric cytosensor for detection of coliforms
M Sedki, X Chen, C Chen, X Ge, A Mulchandani
Biosensors and Bioelectronics 148, 111794, 2020
632020
Potent neutralization of SARS-CoV-2 by human antibody heavy-chain variable domains isolated from a large library with a new stable scaffold
Z Sun, C Chen, W Li, DR Martinez, A Drelich, DS Baek, X Liu, JW Mellors, ...
MAbs 12 (1), 1778435, 2020
622020
Functional selection of protease inhibitory antibodies
T Lopez, Z Mustafa, C Chen, KB Lee, A Ramirez, C Benitez, X Luo, RR Ji, ...
Proceedings of the National Academy of Sciences 116 (33), 16314-16319, 2019
362019
Enhanced elicitation of potent neutralizing antibodies by the SARS-CoV-2 spike receptor binding domain Fc fusion protein in mice
X Liu, A Drelich, W Li, C Chen, Z Sun, M Shi, C Adams, JW Mellors, ...
Vaccine 38 (46), 7205-7212, 2020
322020
Potent neutralization of SARS-CoV-2 in vitro and in an animal model by a human monoclonal antibody
W Li, A Drelich, DR Martinez, L Gralinski, C Chen, Z Sun, X Liu, D Zhelev, ...
BioRxiv 93088, 2020
252020
Affinity maturation of anti-TNF-alpha scFv with somatic hypermutation in non-B cells
S Chen, J Qiu, C Chen, C Liu, Y Liu, L An, J Jia, J Tang, L Wu, H Hang
Protein & cell 3 (6), 460-469, 2012
252012
Coupling recombinase‐mediated cassette exchange with somatic hypermutation for antibody affinity maturation in CHO cells
C Chen, N Li, Y Zhao, H Hang
Biotechnology and bioengineering 113 (1), 39-51, 2016
162016
Host-derived CD70 suppresses murine graft-versus-host disease by limiting donor T cell expansion and effector function
ND Leigh, RE O’Neill, W Du, C Chen, J Qiu, JD Ashwell, PL McCarthy, ...
The Journal of Immunology 199 (1), 336-347, 2017
152017
Rapid selection of a human monoclonal antibody that potently neutralizes SARS-CoV-2 in two animal models
W Li, A Drelich, DR Martinez, L Gralinski, C Chen, Z Sun, A Schäfer, ...
BioRxiv, 2020.05. 13.093088, 2020
132020
Use of a novel camelid-inspired human antibody demonstrates the importance of MMP-14 to cancer stem cell function in the metastatic process
KHE Chen, C Chen, T Lopez, KC Radecki, K Bustamante, MY Lorenson, ...
Oncotarget 9 (50), 29431, 2018
132018
Serine protease inhibitor 6 protects alloreactive T cells from Granzyme B-mediated mitochondrial damage without affecting graft-versus-tumor effect
W Du, H Mohammadpour, RE O'Neill, S Kumar, C Chen, M Qiu, L Mei, ...
Oncoimmunology 7 (3), e1397247, 2018
112018
Neutralization of European, South African, and United States SARS-CoV-2 mutants by a human antibody and antibody domains
Z Sun, A Kim, MD Sobolewski, N Enick, C Chen, C Adams, JL Jacobs, ...
BioRxiv, 2021.03. 22.436481, 2021
102021
Epitope‐specific affinity maturation improved stability of potent protease inhibitory antibodies
T Lopez, C Chuan, A Ramirez, KHE Chen, MY Lorenson, C Benitez, ...
Biotechnology and bioengineering 115 (11), 2673-2682, 2018
72018
Effective killing of cells expressing CD276 (B7-H3) by a bispecific T cell engager based on a new fully human antibody
X Liu, D Zhelev, C Adams, C Chen, JW Mellors, DS Dimitrov
Translational Oncology 14 (12), 101232, 2021
62021
Molecules that bind to SARS-CoV-2
DS Dimitrov, C Chen, DV Jelev, JW Mellors, W Li, Z Sun
US Patent 10,822,379, 2020
52020
Protocol for constructing large size human antibody heavy chain variable domain (VH) library and selection of SARS-CoV-2 neutralizing antibody domains
C Chen, Z Sun, X Liu, W Li, DS Dimitrov
STAR protocols 2 (3), 100617, 2021
42021
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Articles 1–20