Patrick A hughes
Patrick A hughes
Verified email at adelaide.edu.au - Homepage
TitleCited byYear
The ion channel TRPA1 is required for normal mechanosensation and is modulated by algesic stimuli
SM Brierley, PA Hughes, AJ Page, KY Kwan, CM Martin, TA O'Donnell, ...
Gastroenterology 137 (6), 2084-2095. e3, 2009
2202009
Selective role for TRPV4 ion channels in visceral sensory pathways
SM Brierley, AJ Page, PA Hughes, B Adam, T Liebregts, NJ Cooper, ...
Gastroenterology 134 (7), 2059-2069, 2008
2122008
Linaclotide inhibits colonic nociceptors and relieves abdominal pain via guanylate cyclase-C and extracellular cyclic guanosine 3′, 5′-monophosphate
J Castro, AM Harrington, PA Hughes, CM Martin, P Ge, CM Shea, H Jin, ...
Gastroenterology 145 (6), 1334-1346. e11, 2013
1652013
Post-inflammatory colonic afferent sensitisation: different subtypes, different pathways and different time courses
PA Hughes, SM Brierley, CM Martin, SJH Brookes, DR Linden, ...
Gut 58 (10), 1333-1341, 2009
1232009
Sensory neuro-immune interactions differ between irritable bowel syndrome subtypes
PA Hughes, AM Harrington, J Castro, T Liebregts, B Adam, DJ Grasby, ...
Gut 62 (10), 1456-1465, 2013
1222013
Immune activation in irritable bowel syndrome: can neuroimmune interactions explain symptoms?
PA Hughes, H Zola, IA Penttila, LA Blackshaw, JM Andrews, ...
The American journal of gastroenterology 108 (7), 1066, 2013
1122013
A novel role for TRPM8 in visceral afferent function
AM Harrington, PA Hughes, CM Martin, J Yang, J Castro, NJ Isaacs, ...
Pain® 152 (7), 1459-1468, 2011
1062011
TRPA1 contributes to specific mechanically activated currents and sensory neuron mechanical hypersensitivity
SM Brierley, J Castro, AM Harrington, PA Hughes, AJ Page, GY Rychkov, ...
The Journal of physiology 589 (14), 3575-3593, 2011
1002011
Localization and comparative analysis of acid‐sensing ion channel (ASIC1, 2, and 3) mRNA expression in mouse colonic sensory neurons within thoracolumbar dorsal root ganglia
PA Hughes, SM Brierley, RL Young, LA Blackshaw
Journal of Comparative Neurology 500 (5), 863-875, 2007
822007
TRP channels: new targets for visceral pain
LA Blackshaw, SM Brierley, PA Hughes
Gut 59 (01), 126-135, 2010
632010
Acid sensing ion channels 2 and 3 are required for inhibition of visceral nociceptors by benzamil
AJ Page, SM Brierley, CM Martin, PA Hughes, LA Blackshaw
PAIN® 133 (1-3), 150-160, 2007
602007
Involvement of metabotropic glutamate 5 receptor in visceral pain
E Lindström, M Brusberg, PA Hughes, CM Martin, SM Brierley, BD Phillis, ...
PAIN® 137 (2), 295-305, 2008
562008
TRPV1-expressing sensory fibres and IBS: links with immune function
PA Hughes, SM Brierley, CM Martin, T Liebregts, J Persson, B Adam, ...
Gut 58 (3), 465-466, 2009
472009
Post‐inflammatory modification of colonic afferent mechanosensitivity
PA Hughes, SM Brierley, LA Blackshaw
Clinical and Experimental Pharmacology and Physiology 36 (10), 1034-1040, 2009
412009
Cognitive-behavioural therapy has no effect on disease activity but improves quality of life in subgroups of patients with inflammatory bowel disease: a pilot randomised …
A Mikocka-Walus, P Bampton, D Hetzel, P Hughes, A Esterman, ...
BMC gastroenterology 15 (1), 54, 2015
382015
Effect of fecal microbiota transplantation on 8-week remission in patients with ulcerative colitis: a randomized clinical trial
SP Costello, PA Hughes, O Waters, RV Bryant, AD Vincent, P Blatchford, ...
Jama 321 (2), 156-164, 2019
362019
Immune derived opioidergic inhibition of viscerosensory afferents is decreased in Irritable Bowel Syndrome patients
PA Hughes, M Moretta, A Lim, DJ Grasby, D Bird, SM Brierley, T Liebregts, ...
Brain, behavior, and immunity 42, 191-203, 2014
352014
Increased κ-opioid receptor expression and function during chronic visceral hypersensitivity
PA Hughes, J Castro, AM Harrington, N Isaacs, M Moretta, GA Hicks, ...
Gut 63 (7), 1199-1200, 2014
332014
Short duration, low intensity, pooled fecal microbiota transplantation induces remission in patients with mild-moderately active ulcerative colitis: a randomised controlled trial
SP Costello, O Waters, RV Bryant, R Katsikeros, J Makanyanga, ...
Gastroenterology 152 (5), S198-S199, 2017
312017
Deletion of interleukin-6 signal transducer gp130 in small sensory neurons attenuates mechanonociception and down-regulates TRPA1 expression
P Malsch, M Andratsch, C Vogl, AS Link, C Alzheimer, SM Brierley, ...
Journal of Neuroscience 34 (30), 9845-9856, 2014
302014
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Articles 1–20