Felix A Krüger
Felix A Krüger
Bioinformatics, benevolent.ai
Verified email at benevolent.ai - Homepage
Title
Cited by
Cited by
Year
The ChEMBL bioactivity database: an update
AP Bento, A Gaulton, A Hersey, LJ Bellis, J Chambers, M Davies, ...
Nucleic acids research 42 (D1), D1083-D1090, 2014
10552014
The druggable genome and support for target identification and validation in drug development
C Finan, A Gaulton, FA Kruger, RT Lumbers, T Shah, J Engmann, ...
Science translational medicine 9 (383), eaag1166, 2017
1012017
Plasma urate concentration and risk of coronary heart disease: a Mendelian randomisation analysis
J White, R Sofat, G Hemani, T Shah, J Engmann, C Dale, S Shah, ...
The lancet Diabetes & endocrinology 4 (4), 327-336, 2016
792016
Global analysis of small molecule binding to related protein targets
FA Kruger, JP Overington
PLoS computational biology 8 (1), 2012
402012
Collation and data-mining of literature bioactivity data for drug discovery
LJ Bellis, R Akhtar, B Al-Lazikani, F Atkinson, AP Bento, J Chambers, ...
Biochemical Society Transactions 39 (5), 1365-1370, 2011
362011
Mapping small molecule binding data to structural domains
FA Kruger, R Rostom, JP Overington
BMC bioinformatics 13 (17), S11, 2012
192012
Structural and functional view of polypharmacology
A Moya-García, T Adeyelu, FA Kruger, NL Dawson, JG Lees, ...
Scientific reports 7 (1), 1-14, 2017
132017
PPDMs—a resource for mapping small molecule bioactivities from ChEMBL to Pfam-A protein domains
FA Kruger, A Gaulton, M Nowotka, JP Overington
Bioinformatics 31 (5), 776-778, 2015
82015
Fragment formal concept analysis accurately classifies compounds with closely related biological activities
F Krüger, E Lounkine, J Bajorath
ChemMedChem: Chemistry Enabling Drug Discovery 4 (7), 1174-1181, 2009
62009
Classification and regression by randomForest
AP Bento, A Gaulton, A Hersey, LJ Bellis, J Chambers, M Davies, ...
Nucleic Acids Res 5 (1), 983-999, 2013
52013
Improving the odds of drug development success through human genomics: modelling study
AD Hingorani, V Kuan, C Finan, FA Kruger, A Gaulton, S Chopade, ...
Scientific Reports 9 (1), 1-25, 2019
12019
ChEMBL-Linking chemistry and biology to enable mapping onto molecular pathways
L Bellis, A Gaulton, A Hersey, AP Bento, J Chambers, M Davies, F Kruger, ...
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 248, 2014
12014
Flipping the odds of drug development success through human genomics
AD Hingorani, V Kuan, C Finan, FA Kruger, A Gaulton, S Chopade, ...
bioRxiv, 170142, 2017
2017
Structural and Functional View of Polypharmacology
AM Garcia, T Adeyelu, NL Dawson, FA Kruger, J Lees, J Overington, ...
BioRxiv, 044289, 2017
2017
Integration and analysis of protein evolutionary relationships and small molecule bioactivity data
F Krüger
University of Cambridge, 2014
2014
Supplementary Information to Structural and Functional View of Polypharmacology
A Moya-Garcia, T Adeyelu, FA Kruger, NL Dawson, JG Lees, ...
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Articles 1–16