Michael Cowley
Michael Cowley
Head of Department and Professor of Medicine, Monash University
Verified email at - Homepage
Cited by
Cited by
Gut hormone PYY3-36 physiologically inhibits food intake
RL Batterham, MA Cowley, CJ Small, H Herzog, MA Cohen, CL Dakin, ...
Nature 418 (6898), 650-654, 2002
Leptin activates anorexigenic POMC neurons through a neural network in the arcuate nucleus
MA Cowley, JL Smart, M Rubinstein, MG Cerdán, S Diano, TL Horvath, ...
Nature 411 (6836), 480-484, 2001
The distribution and mechanism of action of ghrelin in the CNS demonstrates a novel hypothalamic circuit regulating energy homeostasis
MA Cowley, RG Smith, S Diano, M Tschöp, N Pronchuk, KL Grove, ...
Neuron 37 (4), 649-661, 2003
Mechanisms of leptin action and leptin resistance
MG Myers, MA Cowley, H Münzberg
Annu. Rev. Physiol. 70, 537-556, 2008
TD Müller, R Nogueiras, ML Andermann, ZB Andrews, SD Anker, ...
Molecular metabolism 4 (6), 437-460, 2015
Leptin directly activates SF1 neurons in the VMH, and this action by leptin is required for normal body-weight homeostasis
H Dhillon, JM Zigman, C Ye, CE Lee, RA McGovern, V Tang, CD Kenny, ...
Neuron 49 (2), 191-203, 2006
Glucose sensing by POMC neurons regulates glucose homeostasis and is impaired in obesity
LE Parton, CP Ye, R Coppari, PJ Enriori, B Choi, CY Zhang, C Xu, ...
Nature 449 (7159), 228-232, 2007
Integration of NPY, AGRP, and melanocortin signals in the hypothalamic paraventricular nucleus: evidence of a cellular basis for the adipostat
MA Cowley, N Pronchuk, W Fan, DM Dinulescu, WF Colmers, RD Cone
Neuron 24 (1), 155-163, 1999
The arcuate nucleus as a conduit for diverse signals relevant to energy homeostasis
RD Cone, MA Cowley, AA Butler, W Fan, DL Marks, MJ Low
International Journal of Obesity 25 (5), S63-S67, 2001
Insulin action in AgRP-expressing neurons is required for suppression of hepatic glucose production
AC Könner, R Janoschek, L Plum, SD Jordan, E Rother, X Ma, C Xu, ...
Cell metabolism 5 (6), 438-449, 2007
The arcuate nucleus mediates GLP-1 receptor agonist liraglutide-dependent weight loss
A Secher, J Jelsing, AF Baquero, J Hecksher-Sørensen, MA Cowley, ...
The Journal of clinical investigation 124 (10), 4473-4488, 2014
Diet-induced obesity causes severe but reversible leptin resistance in arcuate melanocortin neurons
PJ Enriori, AE Evans, P Sinnayah, EE Jobst, L Tonelli-Lemos, SK Billes, ...
Cell metabolism 5 (3), 181-194, 2007
Activation of central melanocortin pathways by fenfluramine
LK Heisler, MA Cowley, LH Tecott, W Fan, MJ Low, JL Smart, ...
Science 297 (5581), 609-611, 2002
Serotonin reciprocally regulates melanocortin neurons to modulate food intake
LK Heisler, EE Jobst, GM Sutton, L Zhou, E Borok, Z Thornton-Jones, ...
Neuron 51 (2), 239-249, 2006
Synaptic input organization of the melanocortin system predicts diet-induced hypothalamic reactive gliosis and obesity
TL Horvath, B Sarman, C García-Cáceres, PJ Enriori, P Sotonyi, ...
Proceedings of the national academy of sciences 107 (33), 14875-14880, 2010
Hypothalamic POMC neurons promote cannabinoid-induced feeding
M Koch, L Varela, JG Kim, JD Kim, F Hernández-Nuño, SE Simonds, ...
Nature 519 (7541), 45-50, 2015
Leptin and insulin act on POMC neurons to promote the browning of white fat
GT Dodd, S Decherf, K Loh, SE Simonds, F Wiede, E Balland, TL Merry, ...
Cell 160 (1), 88-104, 2015
Leptin resistance and obesity
PJ Enriori, AE Evans, P Sinnayah, MA Cowley
Obesity 14 (S8), 254S-258S, 2006
Acute effects of leptin require PI3K signaling in hypothalamic proopiomelanocortin neurons in mice
JW Hill, KW Williams, C Ye, J Luo, N Balthasar, R Coppari, MA Cowley, ...
The Journal of clinical investigation 118 (5), 1796-1805, 2008
Rational design of a combination medication for the treatment of obesity
FL Greenway, MJ Whitehouse, M Guttadauria, JW Anderson, RL Atkinson, ...
Obesity 17 (1), 30-39, 2009
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