Em. Prof. Brian J Smith
Em. Prof. Brian J Smith
La Trobe Institute for Molecular Science
Verified email at - Homepage
Cited by
Cited by
Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function
L Chen, SN Willis, A Wei, BJ Smith, JI Fletcher, MG Hinds, PM Colman, ...
Molecular cell 17 (3), 393-403, 2005
The B30. 2 domain of pyrin, the familial Mediterranean fever protein, interacts directly with caspase-1 to modulate IL-1β production
JJ Chae, G Wood, SL Masters, K Richard, G Park, BJ Smith, DL Kastner
Proceedings of the National Academy of Sciences 103 (26), 9982-9987, 2006
Bax Crystal Structures Reveal How BH3 Domains Activate Bax and Nucleate Its Oligomerization to Induce Apoptosis
PE Czabotar, D Westphal, G Dewson, S Ma, C Hockings, WD Fairlie, ...
Cell 152 (3), 519-531, 2013
A newly discovered protein export machine in malaria parasites
TF de Koning-Ward, PR Gilson, JA Boddey, M Rug, BJ Smith, ...
Nature 459 (7249), 945-949, 2009
Structural insights into the degradation of Mcl-1 induced by BH3 domains
PE Czabotar, EF Lee, MF van Delft, CL Day, BJ Smith, DCS Huang, ...
Proceedings of the National Academy of Sciences 104 (15), 6217-6222, 2007
How insulin engages its primary binding site on the insulin receptor
JG Menting, J Whittaker, MB Margetts, LJ Whittaker, GKW Kong, BJ Smith, ...
Nature 493 (7431), 241-245, 2013
Structure-guided design of a selective BCL-XL inhibitor
G Lessene, PE Czabotar, BE Sleebs, K Zobel, KN Lowes, JM Adams, ...
Nature chemical biology 9 (6), 390-397, 2013
Crystal structure of ABT-737 complexed with Bcl-xL: implications for selectivity of antagonists of the Bcl-2 family
EF Lee, PE Czabotar, BJ Smith, K Deshayes, K Zobel, PM Colman, ...
Cell Death & Differentiation 14 (9), 1711-1713, 2007
Discovery of a Potent and Selective BCL-XL Inhibitor with In Vivo Activity
ZF Tao, L Hasvold, L Wang, X Wang, AM Petros, CH Park, ER Boghaert, ...
ACS medicinal chemistry letters 5 (10), 1088-1093, 2014
Assigning absolute values to proton affinities: A differentiation between competing scales
BJ Smith, L Radom
Journal of the American Chemical Society 115 (11), 4885-4888, 1993
The structure of the fusion glycoprotein of Newcastle disease virus suggests a novel paradigm for the molecular mechanism of membrane fusion
L Chen, JJ Gorman, J McKimm-Breschkin, LJ Lawrence, PA Tulloch, ...
Structure 9 (3), 255-266, 2001
Transition structures for the interchange of hydrogen atoms within the water dimer
BJ Smith, DJ Swanton, JA Pople, HF Schaefer III, L Radom
The Journal of chemical physics 92, 1240, 1990
Gaussian‐2 (G2) theory: Reduced basis set requirements
LA Curtiss, PC Redfern, BJ Smith, L Radom
The Journal of chemical physics 104, 5148, 1996
Calculation of proton affinities using the G2 (MP2, SVP) procedure
BJ Smith, L Radom
The Journal of Physical Chemistry 99 (17), 6468-6471, 1995
Transferrin receptor 1 is a reticulocyte-specific receptor for Plasmodium vivax
J Gruszczyk, U Kanjee, LJ Chan, S Menant, B Malleret, NTY Lim, ...
Science 359 (6371), 48-55, 2018
High‐Resolution Structural Characterization of a Helical α/β‐Peptide Foldamer Bound to the Anti‐Apoptotic Protein Bcl‐xL
EF Lee, JD Sadowsky, BJ Smith, PE Czabotar, KJ Peterson‐Kaufman, ...
Angewandte Chemie International Edition 48 (24), 4318-4322, 2009
Structural studies of the resistance of influenza virus neuramindase to inhibitors
BJ Smith, JL McKimm-Breshkin, M McDonald, RT Fernley, JN Varghese, ...
Journal of medicinal chemistry 45 (11), 2207-2212, 2002
Protective hinge in insulin opens to enable its receptor engagement
JG Menting, Y Yang, SJ Chan, NB Phillips, BJ Smith, J Whittaker, ...
Proceedings of the National Academy of Sciences 111 (33), E3395-E3404, 2014
Conformational switching of the pseudokinase domain promotes human MLKL tetramerization and cell death by necroptosis
EJ Petrie, JJ Sandow, AV Jacobsen, BJ Smith, MDW Griffin, IS Lucet, ...
Nature communications 9 (1), 2422, 2018
Domain reorientation and rotation of an intracellular assembly regulate conduction in Kir potassium channels
OB Clarke, AT Caputo, AP Hill, JI Vandenberg, BJ Smith, JM Gulbis
Cell 141 (6), 1018-1029, 2010
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