Cholangiocytes act as facultative liver stem cells during impaired hepatocyte regeneration A Raven, WY Lu, TY Man, S Ferreira-Gonzalez, E O’Duibhir, BJ Dwyer, ... Nature 547 (7663), 350-354, 2017 | 482 | 2017 |
Hepatic progenitor cells of biliary origin with liver repopulation capacity WY Lu, TG Bird, L Boulter, A Tsuchiya, AM Cole, T Hay, RV Guest, ... Nature cell biology 17 (8), 971-983, 2015 | 461 | 2015 |
TGFβ inhibition restores a regenerative response in acute liver injury by suppressing paracrine senescence TG Bird, M Müller, L Boulter, DF Vincent, RA Ridgway, ... Science translational medicine 10 (454), eaan1230, 2018 | 206 | 2018 |
Bone marrow injection stimulates hepatic ductular reactions in the absence of injury via macrophage-mediated TWEAK signaling TG Bird, WY Lu, L Boulter, S Gordon-Keylock, RA Ridgway, MJ Williams, ... Proceedings of the National Academy of Sciences 110 (16), 6542-6547, 2013 | 182 | 2013 |
Building consensus on definition and nomenclature of hepatic, pancreatic, and biliary organoids A Marsee, FJM Roos, MMA Verstegen, F Roos, M Verstegen, H Clevers, ... Cell Stem Cell 28 (5), 816-832, 2021 | 168 | 2021 |
Differentiation of progenitors in the liver: a matter of local choice L Boulter, WY Lu, SJ Forbes The Journal of clinical investigation 123 (5), 1867-1873, 2013 | 133 | 2013 |
Paracrine cellular senescence exacerbates biliary injury and impairs regeneration S Ferreira-Gonzalez, WY Lu, A Raven, B Dwyer, TY Man, E O’Duibhir, ... Nature communications 9 (1), 1020, 2018 | 132 | 2018 |
Mesenchymal Stem Cells and Induced Bone Marrow‐Derived Macrophages Synergistically Improve Liver Fibrosis in Mice Y Watanabe, A Tsuchiya, S Seino, Y Kawata, Y Kojima, S Ikarashi, ... Stem cells translational medicine 8 (3), 271-284, 2019 | 131 | 2019 |
Hepatocyte‐Specific β‐Catenin Deletion During Severe Liver Injury Provokes Cholangiocytes to Differentiate Into Hepatocytes JO Russell, WY Lu, H Okabe, M Abrams, M Oertel, M Poddar, S Singh, ... Hepatology 69 (2), 742-759, 2019 | 126 | 2019 |
Interleukin-13 activates distinct cellular pathways leading to ductular reaction, steatosis, and fibrosis RL Gieseck, TR Ramalingam, KM Hart, KM Vannella, DA Cantu, WY Lu, ... Immunity 45 (1), 145-158, 2016 | 126 | 2016 |
Notch3 drives development and progression of cholangiocarcinoma RV Guest, L Boulter, BJ Dwyer, TJ Kendall, TY Man, SE Minnis-Lyons, ... Proceedings of the National Academy of Sciences 113 (43), 12250-12255, 2016 | 92 | 2016 |
Regional Differences in Human Biliary Tissues and Corresponding In Vitro–Derived Organoids CA Rimland, SG Tilson, CM Morell, RA Tomaz, WY Lu, SE Adams, ... Hepatology 73 (1), 247-267, 2021 | 78 | 2021 |
Galectin-3 regulates hepatic progenitor cell expansion during liver injury WC Hsieh, AC Mackinnon, WY Lu, J Jung, L Boulter, NC Henderson, ... Gut 64 (2), 312-321, 2015 | 64 | 2015 |
Polysialic acid/neural cell adhesion molecule modulates the formation of ductular reactions in liver injury A Tsuchiya, WY Lu, B Weinhold, L Boulter, BM Stutchfield, MJ Williams, ... Hepatology 60 (5), 1727-1740, 2014 | 54 | 2014 |
Expansion, in vivo–ex vivo cycling, and genetic manipulation of primary human hepatocytes E Michailidis, K Vercauteren, L Mancio-Silva, L Andrus, C Jahan, ... Proceedings of the National Academy of Sciences 117 (3), 1678-1688, 2020 | 49 | 2020 |
Peribiliary gland niche participates in biliary tree regeneration in mouse and in human primary sclerosing cholangitis G Carpino, L Nevi, D Overi, V Cardinale, WY Lu, S Di Matteo, S Safarikia, ... Hepatology 71 (3), 972-989, 2020 | 48 | 2020 |
Liver stem cells: Plasticity of the liver epithelium A Tsuchiya, WY Lu World Journal of Gastroenterology 25 (9), 1037, 2019 | 34 | 2019 |
Human biliary epithelial cells from discarded donor livers rescue bile duct structure and function in a mouse model of biliary disease JM Hallett, S Ferreira-Gonzalez, TY Man, AM Kilpatrick, H Esser, ... Cell stem cell 29 (3), 355-371. e10, 2022 | 25 | 2022 |
Notch-IGF1 signaling during liver regeneration drives biliary epithelial cell expansion and inhibits hepatocyte differentiation SE Minnis-Lyons, S Ferreira-González, N Aleksieva, TY Man, VL Gadd, ... Science signaling 14 (688), eaay9185, 2021 | 25 | 2021 |
The role of stem cells in liver injury and repair A Boyd, P Newsome, WY Lu Expert review of gastroenterology & hepatology 13 (7), 623-631, 2019 | 18 | 2019 |