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Wei-Yu Lu
Wei-Yu Lu
MRC Career Development Fellow, University of Edinburgh
Verified email at ed.ac.uk
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Cited by
Year
Cholangiocytes act as facultative liver stem cells during impaired hepatocyte regeneration
A Raven, WY Lu, TY Man, S Ferreira-Gonzalez, E O’Duibhir, BJ Dwyer, ...
Nature 547 (7663), 350-354, 2017
4822017
Hepatic progenitor cells of biliary origin with liver repopulation capacity
WY Lu, TG Bird, L Boulter, A Tsuchiya, AM Cole, T Hay, RV Guest, ...
Nature cell biology 17 (8), 971-983, 2015
4612015
TGFβ inhibition restores a regenerative response in acute liver injury by suppressing paracrine senescence
TG Bird, M Müller, L Boulter, DF Vincent, RA Ridgway, ...
Science translational medicine 10 (454), eaan1230, 2018
2062018
Bone marrow injection stimulates hepatic ductular reactions in the absence of injury via macrophage-mediated TWEAK signaling
TG Bird, WY Lu, L Boulter, S Gordon-Keylock, RA Ridgway, MJ Williams, ...
Proceedings of the National Academy of Sciences 110 (16), 6542-6547, 2013
1822013
Building consensus on definition and nomenclature of hepatic, pancreatic, and biliary organoids
A Marsee, FJM Roos, MMA Verstegen, F Roos, M Verstegen, H Clevers, ...
Cell Stem Cell 28 (5), 816-832, 2021
1682021
Differentiation of progenitors in the liver: a matter of local choice
L Boulter, WY Lu, SJ Forbes
The Journal of clinical investigation 123 (5), 1867-1873, 2013
1332013
Paracrine cellular senescence exacerbates biliary injury and impairs regeneration
S Ferreira-Gonzalez, WY Lu, A Raven, B Dwyer, TY Man, E O’Duibhir, ...
Nature communications 9 (1), 1020, 2018
1322018
Mesenchymal Stem Cells and Induced Bone Marrow‐Derived Macrophages Synergistically Improve Liver Fibrosis in Mice
Y Watanabe, A Tsuchiya, S Seino, Y Kawata, Y Kojima, S Ikarashi, ...
Stem cells translational medicine 8 (3), 271-284, 2019
1312019
Hepatocyte‐Specific β‐Catenin Deletion During Severe Liver Injury Provokes Cholangiocytes to Differentiate Into Hepatocytes
JO Russell, WY Lu, H Okabe, M Abrams, M Oertel, M Poddar, S Singh, ...
Hepatology 69 (2), 742-759, 2019
1262019
Interleukin-13 activates distinct cellular pathways leading to ductular reaction, steatosis, and fibrosis
RL Gieseck, TR Ramalingam, KM Hart, KM Vannella, DA Cantu, WY Lu, ...
Immunity 45 (1), 145-158, 2016
1262016
Notch3 drives development and progression of cholangiocarcinoma
RV Guest, L Boulter, BJ Dwyer, TJ Kendall, TY Man, SE Minnis-Lyons, ...
Proceedings of the National Academy of Sciences 113 (43), 12250-12255, 2016
922016
Regional Differences in Human Biliary Tissues and Corresponding In Vitro–Derived Organoids
CA Rimland, SG Tilson, CM Morell, RA Tomaz, WY Lu, SE Adams, ...
Hepatology 73 (1), 247-267, 2021
782021
Galectin-3 regulates hepatic progenitor cell expansion during liver injury
WC Hsieh, AC Mackinnon, WY Lu, J Jung, L Boulter, NC Henderson, ...
Gut 64 (2), 312-321, 2015
642015
Polysialic acid/neural cell adhesion molecule modulates the formation of ductular reactions in liver injury
A Tsuchiya, WY Lu, B Weinhold, L Boulter, BM Stutchfield, MJ Williams, ...
Hepatology 60 (5), 1727-1740, 2014
542014
Expansion, in vivo–ex vivo cycling, and genetic manipulation of primary human hepatocytes
E Michailidis, K Vercauteren, L Mancio-Silva, L Andrus, C Jahan, ...
Proceedings of the National Academy of Sciences 117 (3), 1678-1688, 2020
492020
Peribiliary gland niche participates in biliary tree regeneration in mouse and in human primary sclerosing cholangitis
G Carpino, L Nevi, D Overi, V Cardinale, WY Lu, S Di Matteo, S Safarikia, ...
Hepatology 71 (3), 972-989, 2020
482020
Liver stem cells: Plasticity of the liver epithelium
A Tsuchiya, WY Lu
World Journal of Gastroenterology 25 (9), 1037, 2019
342019
Human biliary epithelial cells from discarded donor livers rescue bile duct structure and function in a mouse model of biliary disease
JM Hallett, S Ferreira-Gonzalez, TY Man, AM Kilpatrick, H Esser, ...
Cell stem cell 29 (3), 355-371. e10, 2022
252022
Notch-IGF1 signaling during liver regeneration drives biliary epithelial cell expansion and inhibits hepatocyte differentiation
SE Minnis-Lyons, S Ferreira-González, N Aleksieva, TY Man, VL Gadd, ...
Science signaling 14 (688), eaay9185, 2021
252021
The role of stem cells in liver injury and repair
A Boyd, P Newsome, WY Lu
Expert review of gastroenterology & hepatology 13 (7), 623-631, 2019
182019
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