|Combinatorial transcriptional control in blood stem/progenitor cells: genome-wide analysis of ten major transcriptional regulators|
NK Wilson, SD Foster, X Wang, K Knezevic, J Schütte, P Kaimakis, ...
Cell stem cell 7 (4), 532-544, 2010
|Adult cardiac-resident MSC-like stem cells with a proepicardial origin|
JJH Chong, V Chandrakanthan, M Xaymardan, NS Asli, J Li, I Ahmed, ...
Cell stem cell 9 (6), 527-540, 2011
|Myelodysplastic syndromes are propagated by rare and distinct human cancer stem cells in vivo|
PS Woll, U Kjällquist, O Chowdhury, H Doolittle, DC Wedge, S Thongjuea, ...
Cancer cell 25 (6), 794-808, 2014
|Gata2, Fli1, and Scl form a recursively wired gene-regulatory circuit during early hematopoietic development|
JE Pimanda, K Ottersbach, K Knezevic, S Kinston, WYI Chan, NK Wilson, ...
Proceedings of the National Academy of Sciences 104 (45), 17692-17697, 2007
|Origins and functional consequences of somatic mitochondrial DNA mutations in human cancer|
YS Ju, LB Alexandrov, M Gerstung, I Martincorena, S Nik-Zainal, ...
Elife 3, e02935, 2014
|Differential DNA repair underlies mutation hotspots at active promoters in cancer genomes|
D Perera, RC Poulos, A Shah, D Beck, JE Pimanda, JWH Wong
Nature 532 (7598), 259-263, 2016
|Cancerous inhibitor of protein phosphatase 2A, an emerging human oncoprotein and a potential cancer therapy target|
A Khanna, JE Pimanda, J Westermarck
Cancer research 73 (22), 6548-6553, 2013
|The SCL transcriptional network and BMP signaling pathway interact to regulate RUNX1 activity|
JE Pimanda, IJ Donaldson, MFTR De Bruijn, S Kinston, K Knezevic, ...
Proceedings of the National Academy of Sciences 104 (3), 840-845, 2007
|The proto-oncogene ERG in megakaryoblastic leukemias|
L Rainis, T Toki, JE Pimanda, E Rosenthal, K Machol, S Strehl, ...
Cancer research 65 (17), 7596-7602, 2005
|Epigenetic silencing of BIM in glucocorticoid poor-responsive pediatric acute lymphoblastic leukemia, and its reversal by histone deacetylase inhibition|
PS Bachmann, RG Piazza, ME Janes, NC Wong, C Davies, A Mogavero, ...
Blood, The Journal of the American Society of Hematology 116 (16), 3013-3022, 2010
|Genome-wide analysis of transcriptional regulators in human HSPCs reveals a densely interconnected network of coding and noncoding genes|
D Beck, JAI Thoms, D Perera, J Schütte, A Unnikrishnan, K Knezevic, ...
Blood, The Journal of the American Society of Hematology 122 (14), e12-e22, 2013
|Congenital thrombotic thrombocytopenic purpura in association with a mutation in the second CUB domain of ADAMTS13|
JE Pimanda, A Maekawa, T Wind, J Paxton, CN Chesterman, PJ Hogg
Blood 103 (2), 627-629, 2004
|Whole-transcriptome analysis of endothelial to hematopoietic stem cell transition reveals a requirement for Gpr56 in HSC generation|
P Solaimani Kartalaei, T Yamada-Inagawa, CS Vink, E de Pater, ...
Journal of Experimental Medicine 212 (1), 93-106, 2015
|ERG dependence distinguishes developmental control of hematopoietic stem cell maintenance from hematopoietic specification|
S Taoudi, T Bee, A Hilton, K Knezevic, J Scott, TA Willson, C Collin, ...
Genes & development 25 (3), 251-262, 2011
|Opposing regulation of BIM and BCL2 controls glucocorticoid-induced apoptosis of pediatric acute lymphoblastic leukemia cells|
D Jing, VA Bhadri, D Beck, JAI Thoms, NA Yakob, JWH Wong, K Knezevic, ...
Blood 125 (2), 273-283, 2015
|Runx genes are direct targets of Scl/Tal1 in the yolk sac and fetal liver|
JR Landry, S Kinston, K Knezevic, MFTR de Bruijn, N Wilson, ...
Blood, The Journal of the American Society of Hematology 111 (6), 3005-3014, 2008
|ERG promotes T-acute lymphoblastic leukemia and is transcriptionally regulated in leukemic cells by a stem cell enhancer|
JAI Thoms, Y Birger, S Foster, K Knezevic, Y Kirschenbaum, ...
Blood 117 (26), 7079-7089, 2011
|The paralogous hematopoietic regulators Lyl1 and Scl are coregulated by Ets and GATA factors, but Lyl1 cannot rescue the early Scl–/– phenotype|
WYI Chan, GA Follows, G Lacaud, JE Pimanda, JR Landry, S Kinston, ...
Blood 109 (5), 1908-1916, 2007
|The non-coding RNA landscape of human hematopoiesis and leukemia|
A Schwarzer, S Emmrich, F Schmidt, D Beck, M Ng, C Reimer, FF Adams, ...
Nature communications 8 (1), 1-17, 2017
|A common origin of the 4143insA ADAMTS13 mutation|
R Schneppenheim, JAK Hovinga, T Becker, U Budde, D Karpman, ...
Thrombosis and haemostasis 96 (07), 3-6, 2006