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| Origins and functional consequences of somatic mitochondrial DNA mutations in human cancer YS Ju, LB Alexandrov, M Gerstung, I Martincorena, S Nik-Zainal, ... elife 3, e02935, 2014 | 392 | 2014 |
| Analysing high-throughput sequencing data in Python with HTSeq 2.0 GH Putri, S Anders, PT Pyl, JE Pimanda, F Zanini Bioinformatics 38 (10), 2943-2945, 2022 | 384 | 2022 |
| Myelodysplastic syndromes are propagated by rare and distinct human cancer stem cells in vivo PS Woll, U Kjällquist, O Chowdhury, H Doolittle, DC Wedge, S Thongjuea, ... Cancer cell 25 (6), 794-808, 2014 | 355 | 2014 |
| Gata2, Fli1, and Scl form a recursively wired gene-regulatory circuit during early hematopoietic development JE Pimanda, K Ottersbach, K Knezevic, S Kinston, WYI Chan, NK Wilson, ... Proceedings of the National Academy of Sciences 104 (45), 17692-17697, 2007 | 273 | 2007 |
| A menin-MLL inhibitor induces specific chromatin changes and eradicates disease in models of MLL-rearranged leukemia AV Krivtsov, K Evans, JY Gadrey, BK Eschle, C Hatton, HJ Uckelmann, ... Cancer cell 36 (6), 660-673. e11, 2019 | 265 | 2019 |
| Differential DNA repair underlies mutation hotspots at active promoters in cancer genomes D Perera, RC Poulos, A Shah, D Beck, JE Pimanda, JWH Wong Nature 532 (7598), 259-263, 2016 | 232 | 2016 |
| Cancerous inhibitor of protein phosphatase 2A, an emerging human oncoprotein and a potential cancer therapy target A Khanna, JE Pimanda, J Westermarck Cancer research 73 (22), 6548-6553, 2013 | 211 | 2013 |
| The non-coding RNA landscape of human hematopoiesis and leukemia A Schwarzer, S Emmrich, F Schmidt, D Beck, M Ng, C Reimer, FF Adams, ... Nature communications 8 (1), 1-17, 2017 | 156 | 2017 |
| Genome-wide analysis of transcriptional regulators in human HSPCs reveals a densely interconnected network of coding and noncoding genes D Beck, JAI Thoms, D Perera, J Schütte, A Unnikrishnan, K Knezevic, ... Blood, The Journal of the American Society of Hematology 122 (14), e12-e22, 2013 | 153 | 2013 |
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| Epigenetic silencing of BIM in glucocorticoid poor-responsive pediatric acute lymphoblastic leukemia, and its reversal by histone deacetylase inhibition PS Bachmann, RG Piazza, ME Janes, NC Wong, C Davies, A Mogavero, ... Blood, The Journal of the American Society of Hematology 116 (16), 3013-3022, 2010 | 140 | 2010 |
| The SCL transcriptional network and BMP signaling pathway interact to regulate RUNX1 activity JE Pimanda, IJ Donaldson, MFTR De Bruijn, S Kinston, K Knezevic, ... Proceedings of the National Academy of Sciences 104 (3), 840-845, 2007 | 136 | 2007 |
| Opposing regulation of BIM and BCL2 controls glucocorticoid-induced apoptosis of pediatric acute lymphoblastic leukemia cells D Jing, VA Bhadri, D Beck, JAI Thoms, NA Yakob, JWH Wong, K Knezevic, ... Blood, The Journal of the American Society of Hematology 125 (2), 273-283, 2015 | 135 | 2015 |
| ERG dependence distinguishes developmental control of hematopoietic stem cell maintenance from hematopoietic specification S Taoudi, T Bee, A Hilton, K Knezevic, J Scott, TA Willson, C Collin, ... Genes & development 25 (3), 251-262, 2011 | 135 | 2011 |
| Whole-transcriptome analysis of endothelial to hematopoietic stem cell transition reveals a requirement for Gpr56 in HSC generation P Solaimani Kartalaei, T Yamada-Inagawa, CS Vink, E de Pater, ... Journal of Experimental Medicine 212 (1), 93-106, 2015 | 131 | 2015 |
| Integrative genomics identifies the molecular basis of resistance to azacitidine therapy in myelodysplastic syndromes A Unnikrishnan, E Papaemmanuil, D Beck, NP Deshpande, A Verma, ... Cell reports 20 (3), 572-585, 2017 | 118 | 2017 |
| ERG promotes T-acute lymphoblastic leukemia and is transcriptionally regulated in leukemic cells by a stem cell enhancer JAI Thoms, Y Birger, S Foster, K Knezevic, Y Kirschenbaum, ... Blood, The Journal of the American Society of Hematology 117 (26), 7079-7089, 2011 | 114 | 2011 |
| Congenital thrombotic thrombocytopenic purpura in association with a mutation in the second CUB domain of ADAMTS13 JE Pimanda, A Maekawa, T Wind, J Paxton, CN Chesterman, PJ Hogg Blood 103 (2), 627-629, 2004 | 112 | 2004 |
