Daytime variation of perioperative myocardial injury in cardiac surgery and its prevention by Rev-Erbα antagonism: a single-centre propensity-matched cohort study and a … D Montaigne, X Marechal, T Modine, A Coisne, S Mouton, G Fayad, ... The Lancet 391 (10115), 59-69, 2018 | 302 | 2018 |
Dynamic hydroxymethylation of deoxyribonucleic acid marks differentiation-associated enhancers AA Serandour, S Avner, F Oger, M Bizot, F Percevault, ... Nucleic acids research 40 (17), 8255-8265, 2012 | 206 | 2012 |
Metformin interferes with bile acid homeostasis through AMPK-FXR crosstalk F Lien, A Berthier, E Bouchaert, C Gheeraert, J Alexandre, G Porez, ... The Journal of clinical investigation 124 (3), 1037-1051, 2014 | 177 | 2014 |
Metabolic and innate immune cues merge into a specific inflammatory response via the UPR DA Mogilenko, JT Haas, L L’homme, S Fleury, S Quemener, ... Cell 177 (5), 1201-1216. e19, 2019 | 126 | 2019 |
Transcriptional network analysis implicates altered hepatic immune function in NASH development and resolution JT Haas, L Vonghia, DA Mogilenko, AN Verrijken, O Molendi-Coste, ... Nature metabolism 1 (6), 604-614, 2019 | 120 | 2019 |
Interspecies NASH disease activity whole-genome profiling identifies a fibrogenic role of PPARα-regulated dermatopontin P Lefebvre, F Lalloyer, E Baugé, M Pawlak, C Gheeraert, H Dehondt, ... JCI insight 2 (13), 2017 | 108 | 2017 |
A dynamic CTCF chromatin binding landscape promotes DNA hydroxymethylation and transcriptional induction of adipocyte differentiation J Dubois-Chevalier, F Oger, H Dehondt, FF Firmin, C Gheeraert, B Staels, ... Nucleic acids research 42 (17), 10943-10959, 2014 | 84 | 2014 |
Glucose sensing O‐GlcNAcylation pathway regulates the nuclear bile acid receptor farnesoid X receptor (FXR) W Berrabah, P Aumercier, C Gheeraert, H Dehondt, E Bouchaert, ... Hepatology 59 (5), 2022-2033, 2014 | 69 | 2014 |
Cell-specific dysregulation of microRNA expression in obese white adipose tissue F Oger, C Gheeraert, D Mogilenko, Y Benomar, O Molendi-Coste, ... The Journal of Clinical Endocrinology & Metabolism 99 (8), 2821-2833, 2014 | 63 | 2014 |
Hepatic PPARα is critical in the metabolic adaptation to sepsis R Paumelle, JT Haas, N Hennuyer, E Baugé, Y Deleye, D Mesotten, ... Journal of hepatology 70 (5), 963-973, 2019 | 60 | 2019 |
Hepatic molecular signatures highlight the sexual dimorphism of nonalcoholic steatohepatitis (NASH) J Vandel, J Dubois‐Chevalier, C Gheeraert, B Derudas, V Raverdy, ... Hepatology 73 (3), 920-936, 2021 | 50 | 2021 |
The nuclear bile acid receptor FXR is a PKA-and FOXA2-sensitive activator of fasting hepatic gluconeogenesis M Ploton, C Mazuy, C Gheeraert, V Dubois, A Berthier, ... Journal of hepatology 69 (5), 1099-1109, 2018 | 47 | 2018 |
Peroxisome proliferator-activated receptor γ regulates genes involved in insulin/insulin-like growth factor signaling and lipid metabolism during adipogenesis through … F Oger, J Dubois-Chevalier, C Gheeraert, S Avner, E Durand, P Froguel, ... Journal of Biological Chemistry 289 (2), 708-722, 2014 | 44 | 2014 |
Combinatorial regulation of hepatic cytoplasmic signaling and nuclear transcriptional events by the OGT/REV-ERBα complex A Berthier, M Vinod, G Porez, A Steenackers, J Alexandre, N Yamakawa, ... Proceedings of the National Academy of Sciences 115 (47), E11033-E11042, 2018 | 41 | 2018 |
The RBM14/CoAA-interacting, long intergenic non-coding RNA Paral1 regulates adipogenesis and coactivates the nuclear receptor PPARγ FF Firmin, F Oger, C Gheeraert, J Dubois-Chevalier, ... Scientific reports 7 (1), 14087, 2017 | 37 | 2017 |
The hepatic orosomucoid/α1-acid glycoprotein gene cluster is regulated by the nuclear bile acid receptor FXR G Porez, B Gross, J Prawitt, C Gheeraert, W Berrabah, J Alexandre, ... Endocrinology 154 (10), 3690-3701, 2013 | 37 | 2013 |
Hepatic transcriptomic signatures of statin treatment are associated with impaired glucose homeostasis in severely obese patients D Margerie, P Lefebvre, V Raverdy, U Schwahn, H Ruetten, P Larsen, ... BMC Medical Genomics 12, 1-10, 2019 | 30 | 2019 |
Endoplasmic reticulum stress actively suppresses hepatic molecular identity in damaged liver V Dubois, C Gheeraert, W Vankrunkelsven, J Dubois‐Chevalier, ... Molecular systems biology 16 (5), e9156, 2020 | 29 | 2020 |
The logic of transcriptional regulator recruitment architecture at cis-regulatory modules controlling liver functions J Dubois-Chevalier, V Dubois, H Dehondt, P Mazrooei, C Mazuy, ... Genome Research 27 (6), 985-996, 2017 | 25 | 2017 |
Nucleotide-binding oligomerization domain 1 (NOD1) modulates liver ischemia reperfusion through the expression adhesion molecules G Lassailly, MB Saleh, N Leleu-Chavain, M Ningarhari, É Gantier, ... Journal of hepatology 70 (6), 1159-1169, 2019 | 22 | 2019 |