Dendritic cell immunotherapy: mapping the way CG Figdor, IJM de Vries, WJ Lesterhuis, CJM Melief Nature medicine 10 (5), 475-480, 2004 | 1277 | 2004 |
Magnetic resonance tracking of dendritic cells in melanoma patients for monitoring of cellular therapy IJM De Vries, WJ Lesterhuis, JO Barentsz, P Verdijk, JH Van Krieken, ... Nature biotechnology 23 (11), 1407-1413, 2005 | 998 | 2005 |
Effective migration of antigen-pulsed dendritic cells to lymph nodes in melanoma patients is determined by their maturation state IJM De Vries, DJEB Krooshoop, NM Scharenborg, WJ Lesterhuis, ... Cancer research 63 (1), 12-17, 2003 | 639 | 2003 |
Cancer immunotherapy–revisited WJ Lesterhuis, JBAG Haanen, CJA Punt Nature reviews Drug discovery 10 (8), 591-600, 2011 | 522 | 2011 |
Molecular pathways: the immunogenic effects of platinum-based chemotherapeutics SV Hato, A Khong, IJM de Vries, WJ Lesterhuis Clinical Cancer Research 20 (11), 2831-2837, 2014 | 463 | 2014 |
Maturation of dendritic cells is a prerequisite for inducing immune responses in advanced melanoma patients IJM de Vries, WJ Lesterhuis, NM Scharenborg, LPH Engelen, DJ Ruiter, ... Clinical cancer research 9 (14), 5091-5100, 2003 | 416 | 2003 |
Programmed death ligand 2 in cancer‐induced immune suppression EN Rozali, SV Hato, BW Robinson, RA Lake, WJ Lesterhuis Journal of Immunology Research 2012 (1), 656340, 2012 | 384 | 2012 |
Platinum-based drugs disrupt STAT6-mediated suppression of immune responses against cancer in humans and mice WJ Lesterhuis, CJA Punt, SV Hato, D Eleveld-Trancikova, BJH Jansen, ... The Journal of clinical investigation 121 (8), 3100-3108, 2011 | 336 | 2011 |
Dendritic cell vaccination in combination with anti-CD25 monoclonal antibody treatment: a phase I/II study in metastatic melanoma patients JFM Jacobs, CJA Punt, WJ Lesterhuis, RPM Sutmuller, HMH Brouwer, ... Clinical Cancer Research 16 (20), 5067-5078, 2010 | 314 | 2010 |
Dynamic versus static biomarkers in cancer immune checkpoint blockade: unravelling complexity WJ Lesterhuis, A Bosco, MJ Millward, M Small, AK Nowak, RA Lake Nature Reviews Drug Discovery 16 (4), 264-272, 2017 | 229 | 2017 |
Limited amounts of dendritic cells migrate into the T-cell area of lymph nodes but have high immune activating potential in melanoma patients P Verdijk, EHJG Aarntzen, WJ Lesterhuis, ACI Boullart, E Kok, ... Clinical Cancer Research 15 (7), 2531-2540, 2009 | 228 | 2009 |
Immunomonitoring tumor-specific T cells in delayed-type hypersensitivity skin biopsies after dendritic cell vaccination correlates with clinical outcome IJM de Vries, MR Bernsen, WJ Lesterhuis, NM Scharenborg, SP Strijk, ... Journal of Clinical Oncology 23 (24), 5779-5787, 2005 | 225 | 2005 |
Route of administration modulates the induction of dendritic cell vaccine–induced antigen-specific T cells in advanced melanoma patients WJ Lesterhuis, IJM de Vries, G Schreibelt, AJA Lambeck, EHJG Aarntzen, ... Clinical Cancer Research 17 (17), 5725-5735, 2011 | 210 | 2011 |
Sensitization to immune checkpoint blockade through activation of a STAT1/NK axis in the tumor microenvironment RM Zemek, E De Jong, WL Chin, IS Schuster, VS Fear, TH Casey, ... Science translational medicine 11 (501), eaav7816, 2019 | 198 | 2019 |
A systematic investigation of the maximum tolerated dose of cytotoxic chemotherapy with and without supportive care in mice WJ Aston, DE Hope, AK Nowak, BW Robinson, RA Lake, WJ Lesterhuis BMC cancer 17, 1-10, 2017 | 197 | 2017 |
Targeting CD4+ T-Helper Cells Improves the Induction of Antitumor Responses in Dendritic Cell–Based Vaccination EHJG Aarntzen, IJM De Vries, WJ Lesterhuis, D Schuurhuis, JFM Jacobs, ... Cancer research 73 (1), 19-29, 2013 | 178 | 2013 |
Synergistic effect of CTLA-4 blockade and cancer chemotherapy in the induction of anti-tumor immunity WJ Lesterhuis, J Salmons, AK Nowak, EN Rozali, A Khong, IM Dick, ... PloS one 8 (4), e61895, 2013 | 175 | 2013 |
Dendritic cell vaccines in melanoma: from promise to proof? WJ Lesterhuis, E Aarntzen, IJM De Vries, DH Schuurhuis, CG Figdor, ... Critical reviews in oncology/hematology 66 (2), 118-134, 2008 | 171 | 2008 |
Phenotypical and functional characterization of clinical grade dendritic cells IJM de Vries, AAO Eggert, NM Scharenborg, JLM Vissers, WJ Lesterhuis, ... Journal of immunotherapy 25 (5), 429-438, 2002 | 162 | 2002 |
Durvalumab with first-line chemotherapy in previously untreated malignant pleural mesothelioma (DREAM): a multicentre, single-arm, phase 2 trial with a safety run-in AK Nowak, WJ Lesterhuis, PS Kok, C Brown, BGM Hughes, DJ Karikios, ... The Lancet Oncology 21 (9), 1213-1223, 2020 | 146 | 2020 |