Sheena McGowan
Sheena McGowan
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Cited by
An overview of the serpin superfamily
RH Law, Q Zhang, S McGowan, AM Buckle, GA Silverman, W Wong, ...
Genome Biol 7 (5), 216, 2006
Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond
WC Van Voorhis, JH Adams, R Adelfio, V Ahyong, MH Akabas, P Alano, ...
PLoS Pathog 12 (7), e1005763, 2016
Handbook on clostridia
P Dürre
CRC Press, 2004
Structural basis for the inhibition of the essential Plasmodium falciparum M1 neutral aminopeptidase
S McGowan, CJ Porter, J Lowther, CM Stack, SJ Golding, ...
Proceedings of the National Academy of Sciences 106 (8), 2537-2542, 2009
Plasmodium falciparum neutral aminopeptidases: new targets for anti-malarials
TS Skinner-Adams, CM Stack, KR Trenholme, CL Brown, J Grembecka, ...
Trends in biochemical sciences 35 (1), 53-61, 2010
Bestatin-based chemical biology strategy reveals distinct roles for malaria M1-and M17-family aminopeptidases
MB Harbut, G Velmourougane, S Dalal, G Reiss, JC Whisstock, O Onder, ...
Proceedings of the National Academy of Sciences 108 (34), E526-E534, 2011
X-ray crystal structure of the streptococcal specific phage lysin PlyC
S McGowan, AM Buckle, MS Mitchell, JT Hoopes, DT Gallagher, ...
Proceedings of the National Academy of Sciences 109 (31), 12752-12757, 2012
The 1.6 Ċ crystal structure of the catalytic domain of PlyB, a bacteriophage lysin active against Bacillus anthracis
CJ Porter, R Schuch, AJ Pelzek, AM Buckle, S McGowan, MCJ Wilce, ...
Journal of molecular biology 366 (2), 540-550, 2007
The Subtilisin-Like Protease AprV2 Is Required for Virulence and Uses a Novel Disulphide-Tethered Exosite to Bind Substrates
RM Kennan, W Wong, OP Dhungyel, X Han, D Wong, D Parker, ...
PLoS pathogens 6 (11), e1001210, 2010
Structure of the Plasmodium falciparum M17 aminopeptidase and significance for the design of drugs targeting the neutral exopeptidases
S McGowan, CA Oellig, WA Birru, TT Caradoc-Davies, CM Stack, ...
Proceedings of the National Academy of Sciences 107 (6), 2449-2454, 2010
Oxidative Deselenization of Selenocysteine: Applications for Programmed Ligation at Serine
LR Malins, NJ Mitchell, S McGowan, RJ Payne
Angewandte Chemie 127 (43), 12907-12912, 2015
M1 aminopeptidases as drug targets: broad applications or therapeutic niche?
N Drinkwater, J Lee, W Yang, TR Malcolm, S McGowan
The FEBS Journal, 2017
Fingerprinting the Substrate Specificity of M1 and M17 Aminopeptidases of Human Malaria, Plasmodium falciparum
M Poreba, S McGowan, TS Skinner-Adams, KR Trenholme, DL Gardiner, ...
PLoS ONE 7 (2), e31938, 2012
Synthesis of new (−)-bestatin-based inhibitor libraries reveals a novel binding mode in the S1 pocket of the essential malaria M1 metalloaminopeptidase
G Velmourougane, MB Harbut, S Dalal, S McGowan, CA Oellig, ...
Journal of medicinal chemistry 54 (6), 1655-1666, 2011
Synthesis and Structure-Activity Relationships of Phosphonic Arginine Mimetics as Inhibitors of the M1 and M17 Aminopeptidases from Plasmodium falciparum
K Kannan Sivaraman, A Paiardini, M Sieńczyk, C Ruggeri, CA Oellig, ...
Journal of Medicinal Chemistry, 2013
Catalytic diversity and cell wall binding repeats in the phage encoded endolysins
SS Broendum, AM Buckle, S McGowan
Molecular microbiology, 2018
Federated repositories of X-ray diffraction images
S Androulakis, J Schmidberger, MA Bate, R DeGori, A Beitz, C Keong, ...
Acta Crystallographica Section D: Biological Crystallography 64 (7), 810-814, 2008
Stonefish toxin defines an ancient branch of the perforin-like superfamily
AM Ellisdon, CF Reboul, S Panjikar, K Huynh, CA Oellig, KL Winter, ...
Proceedings of the National Academy of Sciences 112 (50), 15360-15365, 2015
Two-Pronged Attack: Dual Inhibition of Plasmodium falciparum M1 and M17 Metalloaminopeptidases by a Novel Series of Hydroxamic Acid-Based Inhibitors
SN Mistry, N Drinkwater, C Ruggeri, KK Sivaraman, S Loganathan, ...
Journal of medicinal chemistry 57 (21), 9168-9183, 2014
Potent dual inhibitors of Plasmodium falciparum M1 and M17 aminopeptidases through optimization of S1 pocket interactions
N Drinkwater, NB Vinh, SN Mistry, RS Bamert, C Ruggeri, JP Holleran, ...
European Journal of Medicinal Chemistry, 2016
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