Prof Mark R Hutchinson
Prof Mark R Hutchinson
Director, ARC Centre of Excellence for Nanoscale BioPhotonics (CNBP) & ARC Future Fellow, Adelaide
Verified email at - Homepage
Cited by
Cited by
Pathological pain and the neuroimmune interface
PM Grace, MR Hutchinson, SF Maier, LR Watkins
Nature Reviews Immunology 14 (4), 217-231, 2014
Evidence that opioids may have toll-like receptor 4 and MD-2 effects
MR Hutchinson, Y Zhang, M Shridhar, JH Evans, MM Buchanan, TX Zhao, ...
Brain, behavior, and immunity 24 (1), 83-95, 2010
Non‐stereoselective reversal of neuropathic pain by naloxone and naltrexone: involvement of toll‐like receptor 4 (TLR4)
MR Hutchinson, Y Zhang, K Brown, BD Coats, M Shridhar, PW Sholar, ...
European Journal of Neuroscience 28 (1), 20-29, 2008
Morphine activates neuroinflammation in a manner parallel to endotoxin
X Wang, LC Loram, K Ramos, AJ de Jesus, J Thomas, K Cheng, A Reddy, ...
Proceedings of the National Academy of Sciences 109 (16), 6325-6330, 2012
The “toll” of opioid-induced glial activation: improving the clinical efficacy of opioids by targeting glia
LR Watkins, MR Hutchinson, KC Rice, SF Maier
Trends in pharmacological sciences 30 (11), 581-591, 2009
Glia as the “bad guys”: Implications for improving clinical pain control and the clinical utility of opioids
LR Watkins, MR Hutchinson, A Ledeboer, J Wieseler-Frank, ED Milligan, ...
Brain, behavior, and immunity 21 (2), 131, 2007
Exploring the Neuroimmunopharmacology of Opioids: An Integrative Review of Mechanisms of Central Immune Signaling and Their Implications for Opioid Analgesia
MR Hutchinson, Y Shavit, PM Grace, KC Rice, SF Maier, LR Watkins
Pharmacological Reviews 63 (3), 772-810, 2011
Opioid-induced glial activation: mechanisms of activation and implications for opioid analgesia, dependence, and reward
MR Hutchinson, ST Bland, KW Johnson, KC Rice, SF Maier, LR Watkins
The Scientific World Journal 7, 98-111, 2007
Toll‐like receptor 4 in CNS pathologies
MM Buchanan, M Hutchinson, LR Watkins, H Yin
Journal of neurochemistry 114 (1), 13-27, 2010
Glia: novel counter-regulators of opioid analgesia
LR Watkins, MR Hutchinson, IN Johnston, SF Maier
Trends in neurosciences 28 (12), 661-669, 2005
Proinflammatory cytokines oppose opioid-induced acute and chronic analgesia
MR Hutchinson, BD Coats, SS Lewis, Y Zhang, DB Sprunger, N Rezvani, ...
Brain, behavior, and immunity 22 (8), 1178-1189, 2008
Toll-like receptors in chronic pain
L Nicotra, LC Loram, LR Watkins, MR Hutchinson
Experimental neurology 234 (2), 316-329, 2012
Opioid activation of toll-like receptor 4 contributes to drug reinforcement
MR Hutchinson, AL Northcutt, T Hiranita, X Wang, SS Lewis, J Thomas, ...
Journal of Neuroscience 32 (33), 11187-11200, 2012
Reduction of opioid withdrawal and potentiation of acute opioid analgesia by systemic AV411 (ibudilast)
MR Hutchinson, SS Lewis, BD Coats, DA Skyba, NY Crysdale, ...
Brain, behavior, and immunity 23 (2), 240-250, 2009
“Listening” and “talking” to neurons: Implications of immune activation for pain control and increasing the efficacy of opioids
LR Watkins, MR Hutchinson, ED Milligan, SF Maier
Brain research reviews 56 (1), 148-169, 2007
Evidence that intrathecal morphine-3-glucuronide may cause pain enhancement via toll-like receptor 4/MD-2 and interleukin-1β
SS Lewis, MR Hutchinson, N Rezvani, LC Loram, Y Zhang, SF Maier, ...
Neuroscience 165 (2), 569-583, 2010
Early-life experience decreases drug-induced reinstatement of morphine CPP in adulthood via microglial-specific epigenetic programming of anti-inflammatory IL-10 expression
JM Schwarz, MR Hutchinson, SD Bilbo
Journal of Neuroscience 31 (49), 17835-17847, 2011
Minocycline suppresses morphine-induced respiratory depression, suppresses morphine-induced reward, and enhances systemic morphine-induced analgesia
MR Hutchinson, AL Northcutt, LW Chao, JJ Kearney, Y Zhang, ...
Brain, behavior, and immunity 22 (8), 1248-1256, 2008
DAT isn’t all that: cocaine reward and reinforcement require Toll-like receptor 4 signaling
AL Northcutt, MR Hutchinson, X Wang, MV Baratta, T Hiranita, ...
Molecular psychiatry 20 (12), 1525-1537, 2015
Implications of central immune signaling caused by drugs of abuse: mechanisms, mediators and new therapeutic approaches for prediction and treatment of drug dependence
JK Coller, MR Hutchinson
Pharmacology & therapeutics 134 (2), 219-245, 2012
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