Prof Mark R Hutchinson
Prof Mark R Hutchinson
Director, Centre for Nanoscale BioPhotonics (CNBP) & ARC Future Fellow, School of Medicine
Verified email at adelaide.edu.au - Homepage
TitleCited byYear
Pathological pain and the neuroimmune interface
PM Grace, MR Hutchinson, SF Maier, LR Watkins
Nature Reviews Immunology 14 (4), 217-231, 2014
4442014
Evidence that opioids may have toll-like receptor 4 and MD-2 effects
MR Hutchinson, Y Zhang, M Shridhar, JH Evans, MM Buchanan, TX Zhao, ...
Brain, behavior, and immunity 24 (1), 83-95, 2010
3702010
Glia as the “bad guys”: Implications for improving clinical pain control and the clinical utility of opioids
LR Watkins, MR Hutchinson, A Ledeboer, J Wieseler-Frank, ED Milligan, ...
Brain, behavior, and immunity 21 (2), 131, 2007
3422007
Opioid-induced glial activation: mechanisms of activation and implications for opioid analgesia, dependence, and reward
MR Hutchinson, ST Bland, KW Johnson, KC Rice, SF Maier, LR Watkins
The Scientific World Journal 7, 98-111, 2007
3242007
Non‐stereoselective reversal of neuropathic pain by naloxone and naltrexone: involvement of toll‐like receptor 4 (TLR4)
MR Hutchinson, Y Zhang, K Brown, BD Coats, M Shridhar, PW Sholar, ...
European Journal of Neuroscience 28 (1), 20-29, 2008
3222008
The “toll” of opioid-induced glial activation: improving the clinical efficacy of opioids by targeting glia
LR Watkins, MR Hutchinson, KC Rice, SF Maier
Trends in pharmacological sciences 30 (11), 581-591, 2009
3212009
Glia: novel counter-regulators of opioid analgesia
LR Watkins, MR Hutchinson, IN Johnston, SF Maier
Trends in neurosciences 28 (12), 661-669, 2005
3202005
Exploring the Neuroimmunopharmacology of Opioids: An Integrative Review of Mechanisms of Central Immune Signaling and Their Implications for Opioid Analgesia
MR Hutchinson, Y Shavit, PM Grace, KC Rice, SF Maier, LR Watkins
Pharmacological Reviews 63 (3), 772-810, 2011
2942011
Morphine activates neuroinflammation in a manner parallel to endotoxin
X Wang, LC Loram, K Ramos, AJ de Jesus, J Thomas, K Cheng, A Reddy, ...
Proceedings of the National Academy of Sciences 109 (16), 6325-6330, 2012
2642012
Proinflammatory cytokines oppose opioid-induced acute and chronic analgesia
MR Hutchinson, BD Coats, SS Lewis, Y Zhang, DB Sprunger, N Rezvani, ...
Brain, behavior, and immunity 22 (8), 1178-1189, 2008
2622008
Toll‐like receptor 4 in CNS pathologies
MM Buchanan, M Hutchinson, LR Watkins, H Yin
Journal of neurochemistry 114 (1), 13-27, 2010
2612010
Enduring reversal of neuropathic pain by a single intrathecal injection of adenosine 2A receptor agonists: a novel therapy for neuropathic pain
LC Loram, JA Harrison, EM Sloane, MR Hutchinson, P Sholar, FR Taylor, ...
Journal of Neuroscience 29 (44), 14015-14025, 2009
2532009
“Listening” and “talking” to neurons: Implications of immune activation for pain control and increasing the efficacy of opioids
LR Watkins, MR Hutchinson, ED Milligan, SF Maier
Brain research reviews 56 (1), 148-169, 2007
1962007
Toll-like receptors in chronic pain
L Nicotra, LC Loram, LR Watkins, MR Hutchinson
Experimental neurology 234 (2), 316-329, 2012
1912012
Reduction of opioid withdrawal and potentiation of acute opioid analgesia by systemic AV411 (ibudilast)
MR Hutchinson, SS Lewis, BD Coats, DA Skyba, NY Crysdale, ...
Brain, behavior, and immunity 23 (2), 240-250, 2009
1832009
Opioid activation of toll-like receptor 4 contributes to drug reinforcement
MR Hutchinson, AL Northcutt, T Hiranita, X Wang, SS Lewis, J Thomas, ...
Journal of Neuroscience 32 (33), 11187-11200, 2012
1702012
Minocycline suppresses morphine-induced respiratory depression, suppresses morphine-induced reward, and enhances systemic morphine-induced analgesia
MR Hutchinson, AL Northcutt, LW Chao, JJ Kearney, Y Zhang, ...
Brain, behavior, and immunity 22 (8), 1248-1256, 2008
1542008
Ibudilast (AV-411) a new class therapeutic candidate for neuropathic pain and opioid withdrawal syndromes
A Ledeboer, MR Hutchinson, LR Watkins, KW Johnson
Expert opinion on investigational drugs 16 (7), 935-950, 2007
1502007
Evidence that intrathecal morphine-3-glucuronide may cause pain enhancement via toll-like receptor 4/MD-2 and interleukin-1β
SS Lewis, MR Hutchinson, N Rezvani, LC Loram, Y Zhang, SF Maier, ...
Neuroscience 165 (2), 569-583, 2010
1362010
The cortical innate immune response increases local neuronal excitability leading to seizures
KM Rodgers, MR Hutchinson, A Northcutt, SF Maier, LR Watkins, ...
Brain 132 (9), 2478-2486, 2009
1362009
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