| IL-37 requires the receptors IL-18Rα and IL-1R8 (SIGIRR) to carry out its multifaceted anti-inflammatory program upon innate signal transduction CA Nold-Petry, CY Lo, I Rudloff, KD Elgass, S Li, MP Gantier, ... Nature immunology 16 (4), 354-365, 2015 | 421 | 2015 |
| A common fold mediates vertebrate defense and bacterial attack CJ Rosado, AM Buckle, RHP Law, RE Butcher, WT Kan, CH Bird, K Ung, ... Science 317 (5844), 1548-1551, 2007 | 324 | 2007 |
| The two-stage pathway of ataxin-3 fibrillogenesis involves a polyglutamine-independent step AM Ellisdon, B Thomas, SP Bottomley Journal of Biological Chemistry 281 (25), 16888-16896, 2006 | 214 | 2006 |
| Sus1, Cdc31, and the Sac3 CID region form a conserved interaction platform that promotes nuclear pore association and mRNA export D Jani, S Lutz, NJ Marshall, T Fischer, A Köhler, AM Ellisdon, E Hurt, ... Molecular cell 33 (6), 727-737, 2009 | 158 | 2009 |
| Structural basis for the assembly and nucleic acid binding of the TREX-2 transcription-export complex AM Ellisdon, L Dimitrova, E Hurt, M Stewart Nature structural & molecular biology 19 (3), 328-336, 2012 | 117 | 2012 |
| Mechanisms of ataxin-3 misfolding and fibril formation: kinetic analysis of a disease-associated polyglutamine protein AM Ellisdon, MC Pearce, SP Bottomley Journal of molecular biology 368 (2), 595-605, 2007 | 111 | 2007 |
| Polyglutamine expansion in ataxin-3 does not affect protein stability: implications for misfolding and disease MKM Chow, AM Ellisdon, LD Cabrita, SP Bottomley Journal of Biological Chemistry 279 (46), 47643-47651, 2004 | 100 | 2004 |
| Cell traversal activity is important for Plasmodium falciparum liver infection in humanized mice ASP Yang, MT O’Neill, C Jennison, S Lopaticki, CC Allison, JS Armistead, ... Cell reports 18 (13), 3105-3116, 2017 | 95 | 2017 |
| Human embryonic stem cell models of Huntington disease JC Niclis, AO Trounson, M Dottori, AM Ellisdon, SP Bottomley, Y Verlinsky, ... Reproductive biomedicine online 19 (1), 106-113, 2009 | 91 | 2009 |
| Characterization of the pathoimmunology of necrotizing enterocolitis reveals novel therapeutic opportunities SX Cho, I Rudloff, JC Lao, MA Pang, R Goldberg, CB Bui, CA McLean, ... Nature communications 11 (1), 5794, 2020 | 68 | 2020 |
| Homodimerization attenuates the anti-inflammatory activity of interleukin-37 AM Ellisdon, CA Nold-Petry, L D’Andrea, SX Cho, JC Lao, I Rudloff, ... Science immunology 2 (8), eaaj1548, 2017 | 61 | 2017 |
| Stonefish toxin defines an ancient branch of the perforin-like superfamily AM Ellisdon, CF Reboul, S Panjikar, K Huynh, CA Oellig, KL Winter, ... Proceedings of the National Academy of Sciences 112 (50), 15360-15365, 2015 | 60 | 2015 |
| The phosphatidylinositol (3, 4, 5)-trisphosphate-dependent Rac exchanger 1· Ras-related C3 botulinum toxin substrate 1 (P-Rex1· Rac1) complex reveals the basis of Rac1 … CM Lucato, ML Halls, LM Ooms, HJ Liu, CA Mitchell, JC Whisstock, ... Journal of Biological Chemistry 290 (34), 20827-20840, 2015 | 55 | 2015 |
| Compartmentalization of GPCR signalling controls unique cellular responses AM Ellisdon, ML Halls Biochemical Society Transactions 44 (2), 562-567, 2016 | 49 | 2016 |
| P-Rex1 and P-Rex2 RacGEFs and cancer N Srijakotre, J Man, LM Ooms, CM Lucato, AM Ellisdon, CA Mitchell Biochemical Society Transactions 45 (4), 963-977, 2017 | 45 | 2017 |
| Structural biology of the PCI-protein fold AM Ellisdon, M Stewart Bioarchitecture 2 (4), 118-123, 2012 | 44 | 2012 |
| Structural Basis for the Interaction between Yeast Spt-Ada-Gcn5 Acetyltransferase (SAGA) Complex Components Sgf11 and Sus1 2 AM Ellisdon, D Jani, A Köhler, E Hurt, M Stewart Journal of biological chemistry 285 (6), 3850-3856, 2010 | 42 | 2010 |
| Preassembled GPCR signaling complexes mediate distinct cellular responses to ultralow ligand concentrations S Civciristov, AM Ellisdon, R Suderman, CK Pon, BA Evans, O Kleifeld, ... Science signaling 11 (551), eaan1188, 2018 | 39 | 2018 |
| The structural impact of a polyglutamine tract is location-dependent AL Robertson, J Horne, AM Ellisdon, B Thomas, MJ Scanlon, ... Biophysical journal 95 (12), 5922-5930, 2008 | 38 | 2008 |
| The role of protein misfolding in the pathogenesis of human diseases AM Ellisdon, SP Bottomley IUBMB life 56 (3), 119-123, 2004 | 37 | 2004 |
