| T cell factor 1-expressing memory-like CD8+ T cells sustain the immune response to chronic viral infections DT Utzschneider, M Charmoy, V Chennupati, L Pousse, DP Ferreira, ... Immunity 45 (2), 415-427, 2016 | 837 | 2016 |
| TOX reinforces the phenotype and longevity of exhausted T cells in chronic viral infection F Alfei, K Kanev, M Hofmann, M Wu, HE Ghoneim, P Roelli, ... Nature 571 (7764), 265-269, 2019 | 687 | 2019 |
| Gain of toxicity from ALS/FTD-linked repeat expansions in C9ORF72 is alleviated by antisense oligonucleotides targeting GGGGCC-containing RNAs J Jiang, Q Zhu, TF Gendron, S Saberi, M McAlonis-Downes, A Seelman, ... Neuron 90 (3), 535-550, 2016 | 558 | 2016 |
| MicroRNA-155 is required for effector CD8+ T cell responses to virus infection and cancer JC Dudda, B Salaun, Y Ji, DC Palmer, GC Monnot, E Merck, ... Immunity 38 (4), 742-753, 2013 | 342 | 2013 |
| Precursor exhausted T cells: key to successful immunotherapy? A Kallies, D Zehn, DT Utzschneider Nature Reviews Immunology 20 (2), 128-136, 2020 | 301 | 2020 |
| T cells maintain an exhausted phenotype after antigen withdrawal and population reexpansion DT Utzschneider, A Legat, SA Fuertes Marraco, L Carrié, I Luescher, ... Nature immunology 14 (6), 603-610, 2013 | 294 | 2013 |
| T cell differentiation in chronic infection and cancer: functional adaptation or exhaustion? DE Speiser, DT Utzschneider, SG Oberle, C Münz, P Romero, D Zehn Nature reviews immunology 14 (11), 768-774, 2014 | 293 | 2014 |
| Early precursor T cells establish and propagate T cell exhaustion in chronic infection DT Utzschneider, SS Gabriel, D Chisanga, R Gloury, PM Gubser, ... Nature immunology 21 (10), 1256-1266, 2020 | 192 | 2020 |
| High antigen levels induce an exhausted phenotype in a chronic infection without impairing T cell expansion and survival DT Utzschneider, F Alfei, P Roelli, D Barras, V Chennupati, S Darbre, ... Journal of Experimental Medicine 213 (9), 1819-1834, 2016 | 170 | 2016 |
| Functional avidity: a measure to predict the efficacy of effector T cells? S Vigano, DT Utzschneider, M Perreau, G Pantaleo, D Zehn, A Harari Journal of Immunology Research 2012, 2012 | 149 | 2012 |
| Transforming growth factor-β-regulated mTOR activity preserves cellular metabolism to maintain long-term T cell responses in chronic infection SS Gabriel, C Tsui, D Chisanga, F Weber, M Llano-León, PM Gubser, ... Immunity 54 (8), 1698-1714. e5, 2021 | 90 | 2021 |
| MYB orchestrates T cell exhaustion and response to checkpoint inhibition C Tsui, L Kretschmer, S Rapelius, SS Gabriel, D Chisanga, K Knöpper, ... Nature 609 (7926), 354-360, 2022 | 85 | 2022 |
| Type I interferons induced by endogenous or exogenous viral infections promote metastasis and relapse of leishmaniasis M Rossi, P Castiglioni, MA Hartley, RO Eren, F Prével, C Desponds, ... Proceedings of the National Academy of Sciences 114 (19), 4987-4992, 2017 | 85 | 2017 |
| Active maintenance of T cell memory in acute and chronic viral infection depends on continuous expression of FOXO1 DT Utzschneider, A Delpoux, D Wieland, X Huang, CY Lai, M Hofmann, ... Cell reports 22 (13), 3454-3467, 2018 | 75 | 2018 |
| Continuous activity of Foxo1 is required to prevent anergy and maintain the memory state of CD8+ T cells A Delpoux, RH Michelini, S Verma, CY Lai, KD Omilusik, DT Utzschneider, ... Journal of Experimental Medicine 215 (2), 575-594, 2018 | 73 | 2018 |
| Interdependence of kallikrein-related peptidases in proteolytic networks N Beaufort, K Plaza, D Utzschneider, A Schwarz, JM Burkhart, ... Biological chemistry 391 (5), 581-587, 2010 | 69 | 2010 |
| Type 1 conventional dendritic cells maintain and guide the differentiation of precursors of exhausted T cells in distinct cellular niches S Dähling, AM Mansilla, K Knöpper, A Grafen, DT Utzschneider, M Ugur, ... Immunity 55 (4), 656-670. e8, 2022 | 51 | 2022 |
| NLRC5 shields T lymphocytes from NK-cell-mediated elimination under inflammatory conditions K Ludigs, C Jandus, DT Utzschneider, F Staehli, S Bessoles, AT Dang, ... Nature communications 7 (1), 10554, 2016 | 48 | 2016 |
| Structure-function analyses of human kallikrein-related peptidase 2 establish the 99-loop as master regulator of activity W Skala, DT Utzschneider, V Magdolen, M Debela, S Guo, CS Craik, ... Journal of Biological Chemistry 289 (49), 34267-34283, 2014 | 39 | 2014 |
| Exacerbated leishmaniasis caused by a viral endosymbiont can be prevented by immunization with its viral capsid P Castiglioni, MA Hartley, M Rossi, F Prevel, C Desponds, ... PLoS neglected tropical diseases 11 (1), e0005240, 2017 | 33 | 2017 |
