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Benjamin Porebski
Benjamin Porebski
Sortera Bio
Verified email at sortera.bio
Title
Cited by
Cited by
Year
The role of protein dynamics in the evolution of new enzyme function
E Campbell, M Kaltenbach, GJ Correy, PD Carr, BT Porebski, ...
Nature chemical biology 12 (11), 944-950, 2016
3042016
Consensus protein design
BT Porebski, AM Buckle
Protein Engineering, Design and Selection 29 (7), 245-251, 2016
2162016
Germinal center antibody mutation trajectories are determined by rapid self/foreign discrimination
DL Burnett, DB Langley, P Schofield, JR Hermes, TD Chan, J Jackson, ...
Science 360 (6385), 223-226, 2018
1452018
A synthetic genetic polymer with an uncharged backbone chemistry based on alkyl phosphonate nucleic acids
S Arangundy-Franklin, AI Taylor, BT Porebski, V Genna, S Peak-Chew, ...
Nature chemistry 11 (6), 533-542, 2019
872019
Epitope flexibility and dynamic footprint revealed by molecular dynamics of a pMHC-TCR complex
CF Reboul, GR Meyer, BT Porebski, NA Borg, AM Buckle
PLoS computational biology 8 (3), e1002404, 2012
692012
Modelling of thyroid peroxidase reveals insights into its enzyme function and autoantigenicity
SN Le, BT Porebski, J McCoey, J Fodor, B Riley, M Godlewska, M Gora, ...
PloS one 10 (12), e0142615, 2015
632015
Denisovan, modern human and mouse TNFAIP3 alleles tune A20 phosphorylation and immunity
NW Zammit, OM Siggs, PE Gray, K Horikawa, DB Langley, SN Walters, ...
Nature immunology 20 (10), 1299-1310, 2019
602019
Discovery and evolution of RNA and XNA reverse transcriptase function and fidelity
G Houlihan, S Arangundy-Franklin, BT Porebski, N Subramanian, ...
Nature chemistry 12 (8), 683-690, 2020
572020
Macromolecular condensation buffers intracellular water potential
JL Watson, E Seinkmane, CT Styles, A Mihut, LK Krüger, KE McNally, ...
Nature 623 (7988), 842-852, 2023
542023
Key determinants of selective binding and activation by the monocyte chemoattractant proteins at the chemokine receptor CCR2
ZE Huma, J Sanchez, HD Lim, JL Bridgford, C Huang, BJ Parker, ...
Science signaling 10 (480), eaai8529, 2017
492017
Cofactor-dependent conformational heterogeneity of GAD65 and its role in autoimmunity and neurotransmitter homeostasis
I Kass, DE Hoke, MGS Costa, CF Reboul, BT Porebski, NP Cowieson, ...
Proceedings of the National Academy of Sciences 111 (25), E2524-E2529, 2014
472014
Structural and dynamic properties that govern the stability of an engineered fibronectin type III domain
BT Porebski, AA Nickson, DE Hoke, MR Hunter, L Zhu, S McGowan, ...
Protein Engineering, Design & Selection 28 (3), 67-78, 2015
432015
Reactive centre loop dynamics and serpin specificity
EM Marijanovic, J Fodor, BT Riley, BT Porebski, MGS Costa, I Kass, ...
Scientific reports 9 (1), 3870, 2019
422019
Random-sequence genetic oligomer pools display an innate potential for ligation and recombination
H Mutschler, AI Taylor, BT Porebski, A Lightowlers, G Houlihan, ...
Elife 7, e43022, 2018
422018
Direct and indirect mechanisms of KLK4 inhibition revealed by structure and dynamics
BT Riley, O Ilyichova, MGS Costa, BT Porebski, SJ De Veer, JE Swedberg, ...
Scientific reports 6 (1), 35385, 2016
382016
A redundant role of human thyroid peroxidase propeptide for cellular, enzymatic, and immunological activity
M Godlewska, M Góra, AM Buckle, BT Porebski, EH Kemp, BJ Sutton, ...
Thyroid 24 (2), 371-382, 2014
372014
Critical evaluation of in silico methods for prediction of coiled-coil domains in proteins
C Li, C Ching Han Chang, J Nagel, BT Porebski, M Hayashida, T Akutsu, ...
Briefings in bioinformatics 17 (2), 270-282, 2016
232016
Rapid discovery of high-affinity antibodies via massively parallel sequencing, ribosome display and affinity screening
BT Porebski, M Balmforth, G Browne, A Riley, K Jamali, MJLJ Fürst, ...
Nature biomedical engineering 8 (3), 214-232, 2024
222024
Conformational diversity facilitates antibody mutation trajectories and discrimination between foreign and self-antigens
DL Burnett, P Schofield, DB Langley, J Jackson, K Bourne, E Wilson, ...
Proceedings of the National Academy of Sciences 117 (36), 22341-22350, 2020
222020
Circumventing the stability-function trade-off in an engineered FN3 domain
BT Porebski, PJ Conroy, N Drinkwater, P Schofield, R Vazquez-Lombardi, ...
Protein Engineering, Design and Selection 29 (11), 541-550, 2016
222016
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