| The role of protein dynamics in the evolution of new enzyme function E Campbell, M Kaltenbach, GJ Correy, PD Carr, BT Porebski, ... Nature chemical biology 12 (11), 944-950, 2016 | 285 | 2016 |
| Consensus protein design BT Porebski, AM Buckle Protein Engineering, Design and Selection 29 (7), 245-251, 2016 | 186 | 2016 |
| Germinal center antibody mutation trajectories are determined by rapid self/foreign discrimination DL Burnett, DB Langley, P Schofield, JR Hermes, TD Chan, J Jackson, ... Science 360 (6385), 223-226, 2018 | 140 | 2018 |
| A synthetic genetic polymer with an uncharged backbone chemistry based on alkyl phosphonate nucleic acids S Arangundy-Franklin, AI Taylor, BT Porebski, V Genna, S Peak-Chew, ... Nature chemistry 11 (6), 533-542, 2019 | 77 | 2019 |
| Epitope flexibility and dynamic footprint revealed by molecular dynamics of a pMHC-TCR complex CF Reboul, GR Meyer, BT Porebski, NA Borg, AM Buckle PLoS computational biology 8 (3), e1002404, 2012 | 64 | 2012 |
| Modelling of thyroid peroxidase reveals insights into its enzyme function and autoantigenicity SN Le, BT Porebski, J McCoey, J Fodor, B Riley, M Godlewska, M Gora, ... PloS one 10 (12), e0142615, 2015 | 55 | 2015 |
| Denisovan, modern human and mouse TNFAIP3 alleles tune A20 phosphorylation and immunity NW Zammit, OM Siggs, PE Gray, K Horikawa, DB Langley, SN Walters, ... Nature immunology 20 (10), 1299-1310, 2019 | 54 | 2019 |
| Discovery and evolution of RNA and XNA reverse transcriptase function and fidelity G Houlihan, S Arangundy-Franklin, BT Porebski, N Subramanian, ... Nature chemistry 12 (8), 683-690, 2020 | 50 | 2020 |
| Key determinants of selective binding and activation by the monocyte chemoattractant proteins at the chemokine receptor CCR2 ZE Huma, J Sanchez, HD Lim, JL Bridgford, C Huang, BJ Parker, ... Science signaling 10 (480), eaai8529, 2017 | 45 | 2017 |
| Cofactor-dependent conformational heterogeneity of GAD65 and its role in autoimmunity and neurotransmitter homeostasis I Kass, DE Hoke, MGS Costa, CF Reboul, BT Porebski, NP Cowieson, ... Proceedings of the National Academy of Sciences 111 (25), E2524-E2529, 2014 | 43 | 2014 |
| Random-sequence genetic oligomer pools display an innate potential for ligation and recombination H Mutschler, AI Taylor, BT Porebski, A Lightowlers, G Houlihan, ... Elife 7, e43022, 2018 | 42 | 2018 |
| Structural and dynamic properties that govern the stability of an engineered fibronectin type III domain BT Porebski, AA Nickson, DE Hoke, MR Hunter, L Zhu, S McGowan, ... Protein Engineering, Design & Selection 28 (3), 67-78, 2015 | 39 | 2015 |
| Direct and indirect mechanisms of KLK4 inhibition revealed by structure and dynamics BT Riley, O Ilyichova, MGS Costa, BT Porebski, SJ De Veer, JE Swedberg, ... Scientific reports 6 (1), 35385, 2016 | 35 | 2016 |
| Reactive centre loop dynamics and serpin specificity EM Marijanovic, J Fodor, BT Riley, BT Porebski, MGS Costa, I Kass, ... Scientific reports 9 (1), 3870, 2019 | 34 | 2019 |
| A redundant role of human thyroid peroxidase propeptide for cellular, enzymatic, and immunological activity M Godlewska, M Góra, AM Buckle, BT Porebski, EH Kemp, BJ Sutton, ... Thyroid 24 (2), 371-382, 2014 | 33 | 2014 |
| Conformational diversity facilitates antibody mutation trajectories and discrimination between foreign and self-antigens DL Burnett, P Schofield, DB Langley, J Jackson, K Bourne, E Wilson, ... Proceedings of the National Academy of Sciences 117 (36), 22341-22350, 2020 | 21 | 2020 |
| Circumventing the stability-function trade-off in an engineered FN3 domain BT Porebski, PJ Conroy, N Drinkwater, P Schofield, R Vazquez-Lombardi, ... Protein Engineering, Design and Selection 29 (11), 541-550, 2016 | 21 | 2016 |
| Critical evaluation of in silico methods for prediction of coiled-coil domains in proteins C Li, C Ching Han Chang, J Nagel, BT Porebski, M Hayashida, T Akutsu, ... Briefings in bioinformatics 17 (2), 270-282, 2016 | 21 | 2016 |
| Structural and dynamic requirements for optimal activity of the essential bacterial enzyme dihydrodipicolinate synthase CF Reboul, BT Porebski, MDW Griffin, RCJ Dobson, MA Perugini, ... PLoS computational biology 8 (6), e1002537, 2012 | 20 | 2012 |
| Smoothing a rugged protein folding landscape by sequence-based redesign BT Porebski, S Keleher, JJ Hollins, AA Nickson, EM Marijanovic, NA Borg, ... Scientific Reports 6 (1), 33958, 2016 | 18 | 2016 |
Ashley BuckleReplayVerified email at replay.bio
