|NASH and insulin resistance: insulin hypersecretion and specific association with the insulin resistance syndrome|
S Chitturi, S Abeygunasekera, GC Farrell, J Holmes-Walker, JM Hui, ...
Hepatology 35 (2), 373-379, 2002
|PPARγ signaling and metabolism: the good, the bad and the future|
M Ahmadian, JM Suh, N Hah, C Liddle, AR Atkins, M Downes, RM Evans
Nature medicine 19 (5), 557, 2013
|Orphan nuclear receptors constitutive androstane receptor and pregnane X receptor share xenobiotic and steroid ligands|
LB Moore, DJ Parks, SA Jones, RK Bledsoe, TG Consler, JB Stimmel, ...
Journal of Biological Chemistry 275 (20), 15122-15127, 2000
|The orphan human pregnane X receptor mediates the transcriptional activation of CYP3A4 by rifampicin through a distal enhancer module|
B Goodwin, E Hodgson, C Liddle
Molecular pharmacology 56 (6), 1329-1339, 1999
|Hepatic cytochrome P450 2E1 is increased in patients with nonalcoholic steatohepatitis|
MD Weltman, GC Farrell, P Hall, M Ingelman‐Sundberg, C Liddle
Hepatology 27 (1), 128-133, 1998
|Regulation of circadian behaviour and metabolism by REV-ERB-α and REV-ERB-β|
H Cho, X Zhao, M Hatori, TY Ruth, GD Barish, MT Lam, LW Chong, ...
Nature 485 (7396), 123, 2012
|Serum leptin in NASH correlates with hepatic steatosis but not fibrosis: a manifestation of lipotoxicity?|
S Chitturi, G Farrell, L Frost, A Kriketos, R Lin, C Liddle, D Samarasinghe, ...
Hepatology 36 (2), 403-409, 2002
|Vitamin D receptor-mediated stromal reprogramming suppresses pancreatitis and enhances pancreatic cancer therapy|
MH Sherman, TY Ruth, DD Engle, N Ding, AR Atkins, H Tiriac, ...
Cell 159 (1), 80-93, 2014
|Increased hepatocyte CYP2E1 expression in a rat nutritional model of hepatic steatosis with inflammation|
MD Weltman, GC Farrell, C Liddle
Gastroenterology 111 (6), 1645-1653, 1996
|A vitamin D receptor/SMAD genomic circuit gates hepatic fibrotic response|
N Ding, TY Ruth, N Subramaniam, MH Sherman, C Wilson, R Rao, ...
Cell 153 (3), 601-613, 2013
|Pre-translational regulation of cytochrome P450 genes is responsible for disease-specific changes of individual P450 enzymes among patients with cirrhosis|
J George, C Liddle, M Murray, K Byth, GC Farrell
Biochemical pharmacology 49 (7), 873-881, 1995
|Intestinal FXR agonism promotes adipose tissue browning and reduces obesity and insulin resistance|
S Fang, JM Suh, SM Reilly, E Yu, O Osborn, D Lackey, E Yoshihara, ...
Nature medicine 21 (2), 159, 2015
|Regulation of drug metabolizing enzymes and transporters in infection, inflammation, and cancer|
ET Morgan, CM Lee, BA Nyagode
Encyclopedia of Drug Metabolism and Interactions, 1-45, 2011
|Transcriptional regulation of the human CYP3A4gene by the constitutive androstane receptor|
B Goodwin, E Hodgson, DJ D'Costa, GR Robertson, C Liddle
Molecular pharmacology 62 (2), 359-365, 2002
|HFE mutations, hepatic iron, and fibrosis: ethnic‐specific association of NASH with C282Y but not with fibrotic severity|
S Chitturi, M Weltman, GC Farrell, D McDonald, C Liddle, ...
Hepatology 36 (1), 142-149, 2002
|An inhibitor of the protein kinases TBK1 and IKK-ɛ improves obesity-related metabolic dysfunctions in mice|
SM Reilly, SH Chiang, SJ Decker, L Chang, M Uhm, MJ Larsen, JR Rubin, ...
Nature medicine 19 (3), 313, 2013
|Improved prediction of fibrosis in chronic hepatitis C using measures of insulin resistance in a probability index|
A Sud, JM Hui, GC Farrell, P Bandara, JG Kench, C Fung, R Lin, ...
Hepatology 39 (5), 1239-1247, 2004
|Which patients with hepatitis C develop liver complications?|
MH Khan, GC Farrell, K Byth, R Lin, M Weltman, J George, ...
Hepatology 31 (2), 513-520, 2000
|Coinfection with hepatitis B and C or B, C and δ viruses results in severe chronic liver disease and responds poorly to terferon‐a treatment|
MD Weltman, A Brotodihardjo, EB Crewe, GC Farrell, M Bililus, ...
Journal of viral hepatitis 2 (1), 39-45, 1995
|Nuclear receptors constitutive androstane receptor and pregnane X receptor ameliorate cholestatic liver injury|
CAM Stedman, C Liddle, SA Coulter, J Sonoda, JGA Alvarez, DD Moore, ...
Proceedings of the National Academy of Sciences 102 (6), 2063-2068, 2005