Christopher Liddle
Christopher Liddle
Professor of Clinical Pharmacology and Hepatology, University of Sydney
Verified email at sydney.edu.au - Homepage
TitleCited byYear
NASH and insulin resistance: insulin hypersecretion and specific association with the insulin resistance syndrome
S Chitturi, S Abeygunasekera, GC Farrell, J Holmes-Walker, JM Hui, ...
Hepatology 35 (2), 373-379, 2002
12822002
PPARγ signaling and metabolism: the good, the bad and the future
M Ahmadian, JM Suh, N Hah, C Liddle, AR Atkins, M Downes, RM Evans
Nature medicine 19 (5), 557, 2013
10542013
Orphan nuclear receptors constitutive androstane receptor and pregnane X receptor share xenobiotic and steroid ligands
LB Moore, DJ Parks, SA Jones, RK Bledsoe, TG Consler, JB Stimmel, ...
Journal of Biological Chemistry 275 (20), 15122-15127, 2000
8902000
The orphan human pregnane X receptor mediates the transcriptional activation of CYP3A4 by rifampicin through a distal enhancer module
B Goodwin, E Hodgson, C Liddle
Molecular pharmacology 56 (6), 1329-1339, 1999
7061999
Hepatic cytochrome P450 2E1 is increased in patients with nonalcoholic steatohepatitis
MD Weltman, GC Farrell, P Hall, M Ingelman‐Sundberg, C Liddle
Hepatology 27 (1), 128-133, 1998
6841998
Regulation of circadian behaviour and metabolism by REV-ERB-α and REV-ERB-β
H Cho, X Zhao, M Hatori, TY Ruth, GD Barish, MT Lam, LW Chong, ...
Nature 485 (7396), 123, 2012
6152012
Serum leptin in NASH correlates with hepatic steatosis but not fibrosis: a manifestation of lipotoxicity?
S Chitturi, G Farrell, L Frost, A Kriketos, R Lin, C Liddle, D Samarasinghe, ...
Hepatology 36 (2), 403-409, 2002
4812002
Vitamin D receptor-mediated stromal reprogramming suppresses pancreatitis and enhances pancreatic cancer therapy
MH Sherman, TY Ruth, DD Engle, N Ding, AR Atkins, H Tiriac, ...
Cell 159 (1), 80-93, 2014
4272014
Increased hepatocyte CYP2E1 expression in a rat nutritional model of hepatic steatosis with inflammation
MD Weltman, GC Farrell, C Liddle
Gastroenterology 111 (6), 1645-1653, 1996
4201996
A vitamin D receptor/SMAD genomic circuit gates hepatic fibrotic response
N Ding, TY Ruth, N Subramaniam, MH Sherman, C Wilson, R Rao, ...
Cell 153 (3), 601-613, 2013
3622013
Pre-translational regulation of cytochrome P450 genes is responsible for disease-specific changes of individual P450 enzymes among patients with cirrhosis
J George, C Liddle, M Murray, K Byth, GC Farrell
Biochemical pharmacology 49 (7), 873-881, 1995
3541995
Intestinal FXR agonism promotes adipose tissue browning and reduces obesity and insulin resistance
S Fang, JM Suh, SM Reilly, E Yu, O Osborn, D Lackey, E Yoshihara, ...
Nature medicine 21 (2), 159, 2015
3312015
Regulation of drug metabolizing enzymes and transporters in infection, inflammation, and cancer
ET Morgan, CM Lee, BA Nyagode
Encyclopedia of Drug Metabolism and Interactions, 1-45, 2011
3222011
Transcriptional regulation of the human CYP3A4gene by the constitutive androstane receptor
B Goodwin, E Hodgson, DJ D'Costa, GR Robertson, C Liddle
Molecular pharmacology 62 (2), 359-365, 2002
2562002
HFE mutations, hepatic iron, and fibrosis: ethnic‐specific association of NASH with C282Y but not with fibrotic severity
S Chitturi, M Weltman, GC Farrell, D McDonald, C Liddle, ...
Hepatology 36 (1), 142-149, 2002
2492002
An inhibitor of the protein kinases TBK1 and IKK-ɛ improves obesity-related metabolic dysfunctions in mice
SM Reilly, SH Chiang, SJ Decker, L Chang, M Uhm, MJ Larsen, JR Rubin, ...
Nature medicine 19 (3), 313, 2013
2402013
Improved prediction of fibrosis in chronic hepatitis C using measures of insulin resistance in a probability index
A Sud, JM Hui, GC Farrell, P Bandara, JG Kench, C Fung, R Lin, ...
Hepatology 39 (5), 1239-1247, 2004
2322004
Which patients with hepatitis C develop liver complications?
MH Khan, GC Farrell, K Byth, R Lin, M Weltman, J George, ...
Hepatology 31 (2), 513-520, 2000
2102000
Coinfection with hepatitis B and C or B, C and δ viruses results in severe chronic liver disease and responds poorly to terferon‐a treatment
MD Weltman, A Brotodihardjo, EB Crewe, GC Farrell, M Bililus, ...
Journal of viral hepatitis 2 (1), 39-45, 1995
2031995
Nuclear receptors constitutive androstane receptor and pregnane X receptor ameliorate cholestatic liver injury
CAM Stedman, C Liddle, SA Coulter, J Sonoda, JGA Alvarez, DD Moore, ...
Proceedings of the National Academy of Sciences 102 (6), 2063-2068, 2005
2012005
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Articles 1–20