| NASH and insulin resistance: insulin hypersecretion and specific association with the insulin resistance syndrome S Chitturi, S Abeygunasekera, GC Farrell, J Holmes‐Walker, JM Hui, ... Hepatology 35 (2), 373-379, 2002 | 1346 | 2002 |
| PPARγ signaling and metabolism: the good, the bad and the future M Ahmadian, JM Suh, N Hah, C Liddle, AR Atkins, M Downes, RM Evans Nature medicine 19 (5), 557-566, 2013 | 1175 | 2013 |
| Orphan nuclear receptors constitutive androstane receptor and pregnane X receptor share xenobiotic and steroid ligands LB Moore, DJ Parks, SA Jones, RK Bledsoe, TG Consler, JB Stimmel, ... Journal of Biological Chemistry 275 (20), 15122-15127, 2000 | 905 | 2000 |
| The orphan human pregnane X receptor mediates the transcriptional activation of CYP3A4 by rifampicin through a distal enhancer module B Goodwin, E Hodgson, C Liddle Molecular pharmacology 56 (6), 1329-1339, 1999 | 719 | 1999 |
| Hepatic cytochrome P450 2E1 is increased in patients with nonalcoholic steatohepatitis MD Weltman, GC Farrell, P Hall, M Ingelman‐Sundberg, C Liddle Hepatology 27 (1), 128-133, 1998 | 699 | 1998 |
| Regulation of circadian behaviour and metabolism by REV-ERB-α and REV-ERB-β H Cho, X Zhao, M Hatori, TY Ruth, GD Barish, MT Lam, LW Chong, ... Nature 485 (7396), 123-127, 2012 | 673 | 2012 |
| Vitamin D receptor-mediated stromal reprogramming suppresses pancreatitis and enhances pancreatic cancer therapy MH Sherman, TY Ruth, DD Engle, N Ding, AR Atkins, H Tiriac, ... Cell 159 (1), 80-93, 2014 | 514 | 2014 |
| Serum leptin in NASH correlates with hepatic steatosis but not fibrosis: a manifestation of lipotoxicity? S Chitturi, G Farrell, L Frost, A Kriketos, R Lin, C Liddle, D Samarasinghe, ... Hepatology 36 (2), 403-409, 2002 | 491 | 2002 |
| In vitro and in vivo reversal of P-glycoprotein-mediated multidrug resistance by a novel potent modulator, XR9576 P Mistry, AJ Stewart, W Dangerfield, S Okiji, C Liddle, D Bootle, JA Plumb, ... Cancer research 61 (2), 749-758, 2001 | 460 | 2001 |
| Increased hepatocyte CYP2E1 expression in a rat nutritional model of hepatic steatosis with inflammation MD Weltman, GC Farrell, C Liddle Gastroenterology 111 (6), 1645-1653, 1996 | 438 | 1996 |
| A vitamin D receptor/SMAD genomic circuit gates hepatic fibrotic response N Ding, TY Ruth, N Subramaniam, MH Sherman, C Wilson, R Rao, ... Cell 153 (3), 601-613, 2013 | 402 | 2013 |
| Intestinal FXR agonism promotes adipose tissue browning and reduces obesity and insulin resistance S Fang, JM Suh, SM Reilly, E Yu, O Osborn, D Lackey, E Yoshihara, ... Nature medicine 21 (2), 159, 2015 | 387 | 2015 |
| Pre-translational regulation of cytochrome P450 genes is responsible for disease-specific changes of individual P450 enzymes among patients with cirrhosis J George, C Liddle, M Murray, K Byth, GC Farrell Biochemical pharmacology 49 (7), 873-881, 1995 | 360 | 1995 |
| Regulation of drug metabolizing enzymes and transporters in infection, inflammation, and cancer ET Morgan, CM Lee, BA Nyagode Encyclopedia of Drug Metabolism and Interactions, 1-45, 2011 | 336 | 2011 |
| An inhibitor of the protein kinases TBK1 and IKK-ɛ improves obesity-related metabolic dysfunctions in mice SM Reilly, SH Chiang, SJ Decker, L Chang, M Uhm, MJ Larsen, JR Rubin, ... Nature medicine 19 (3), 313, 2013 | 271 | 2013 |
| Transcriptional regulation of the human CYP3A4gene by the constitutive androstane receptor B Goodwin, E Hodgson, DJ D'Costa, GR Robertson, C Liddle Molecular pharmacology 62 (2), 359-365, 2002 | 263 | 2002 |
| HFE mutations, hepatic iron, and fibrosis: ethnic‐specific association of NASH with C282Y but not with fibrotic severity S Chitturi, M Weltman, GC Farrell, D McDonald, C Liddle, ... Hepatology 36 (1), 142-149, 2002 | 258 | 2002 |
| Improved prediction of fibrosis in chronic hepatitis C using measures of insulin resistance in a probability index A Sud, JM Hui, GC Farrell, P Bandara, JG Kench, C Fung, R Lin, ... Hepatology 39 (5), 1239-1247, 2004 | 237 | 2004 |
| Which patients with hepatitis C develop liver complications? MH Khan, GC Farrell, K Byth, R Lin, M Weltman, J George, ... Hepatology 31 (2), 513-520, 2000 | 217 | 2000 |
| Nuclear receptors constitutive androstane receptor and pregnane X receptor ameliorate cholestatic liver injury CAM Stedman, C Liddle, SA Coulter, J Sonoda, JGA Alvarez, DD Moore, ... Proceedings of the National Academy of Sciences 102 (6), 2063-2068, 2005 | 208 | 2005 |
Ronald M EvansProfessor, Salk InstituteVerified email at salk.edu
