| Reactivation of the p53 tumor suppressor pathway by a stapled p53 peptide F Bernal, AF Tyler, SJ Korsmeyer, LD Walensky, GL Verdine Journal of the American Chemical Society 129 (9), 2456-2457, 2007 | 677 | 2007 |
| MDM4 is a key therapeutic target in cutaneous melanoma A Gembarska, F Luciani, C Fedele, EA Russell, M Dewaele, S Villar, ... Nature medicine 18 (8), 1239-1247, 2012 | 356 | 2012 |
| A stapled p53 helix overcomes HDMX-mediated suppression of p53 F Bernal, M Wade, M Godes, TN Davis, DG Whitehead, AL Kung, ... Cancer cell 18 (5), 411-422, 2010 | 356 | 2010 |
| Essential role of the linear ubiquitin chain assembly complex in lymphoma revealed by rare germline polymorphisms Y Yang, R Schmitz, J Mitala, A Whiting, W Xiao, M Ceribelli, GW Wright, ... Cancer discovery 4 (4), 480-493, 2014 | 174 | 2014 |
| Synthesis and Biophysical Characterization of Stabilized α‐Helices of BCL‐2 Domains GH Bird, F Bernal, K Pitter, LD Walensky Methods in enzymology 446, 369-386, 2008 | 130 | 2008 |
| Total Synthesis of the Proposed Azaspiracid‐1 Structure, Part 1: Construction of the Enantiomerically Pure C1–C20, C21–C27, and C28–C40 Fragments KC Nicolaou, Y Li, N Uesaka, TV Koftis, S Vyskocil, T Ling, ... Angewandte Chemie 115 (31), 3771-3776, 2003 | 110 | 2003 |
| Total synthesis and structural elucidation of azaspiracid-1. Construction of key building blocks for originally proposed structure KC Nicolaou, PM Pihko, F Bernal, MO Frederick, W Qian, N Uesaka, ... Journal of the American Chemical Society 128 (7), 2244-2257, 2006 | 96 | 2006 |
| Cooperative domain formation by homologous motifs in HOIL-1L and SHARPIN plays a crucial role in LUBAC stabilization H Fujita, A Tokunaga, S Shimizu, AL Whiting, F Aguilar-Alonso, K Takagi, ... Cell reports 23 (4), 1192-1204, 2018 | 93 | 2018 |
| Synthesis of the FGHI ring system of azaspiracid KC Nicolaou, PM Pihko, N Diedrichs, N Zou, F Bernal Angewandte Chemie 113 (7), 1302-1305, 2001 | 82 | 2001 |
| Stabilized p53 peptides and uses thereof F Bernal, LD Walensky, GL Verdine, SJ Korsmeyer US Patent 8,889,632, 2014 | 81 | 2014 |
| Total synthesis and structural elucidation of azaspiracid-1. Synthesis-based analysis of originally proposed structures and indication of their non-identity to the natural product KC Nicolaou, DYK Chen, Y Li, N Uesaka, G Petrovic, TV Koftis, F Bernal, ... Journal of the American Chemical Society 128 (7), 2258-2267, 2006 | 70 | 2006 |
| Dissection of the BCL‐2 family signaling network with stabilized α‐helices of BCL‐2 domains K Pitter, F Bernal, J LaBelle, LD Walensky Methods in enzymology 446, 387-408, 2008 | 63 | 2008 |
| Synthesis of the ABCD ring system of azaspiracid KC Nicolaou, W Qian, F Bernal, N Uesaka, PM Pihko, J Hinrichs Angewandte Chemie 113 (21), 4192-4195, 2001 | 62* | 2001 |
| Role of non-genomic androgen signalling in suppressing proliferation of fibroblasts and fibrosarcoma cells G Castoria, P Giovannelli, M Di Donato, A Ciociola, R Hayashi, F Bernal, ... Cell Death & Disease 5 (12), e1548-e1548, 2014 | 47 | 2014 |
| Cancer therapies and diagnostics LD Walensky, F Bernal, G Wahl, M Wade US Patent 10,822,374, 2020 | 45 | 2020 |
| High levels of Hdmx promote cell growth in a subset of uveal melanomas J de Lange, AFAS Teunisse, M Verlaan-de Vries, K Lodder, S Lam, ... American journal of cancer research 2 (5), 492, 2012 | 38 | 2012 |
| Stabilized p53 peptides and uses thereof F Bernal, LD Walensky, GL Verdine, SJ Korsmeyer US Patent 9,527,896, 2016 | 35 | 2016 |
| Synthesis of N-heterocycles via lactam-derived ketene aminal phosphates. Asymmetric synthesis of cyclic amino acids. KC Nicolaou, K Namoto Chemical Communications, 1757-1758, 1998 | 25 | 1998 |
| Stabilized P53 peptides and uses thereof F Bernal, LD Walensky, GL Verdine, SJ Korsmeyer US Patent 10,202,431, 2019 | 22 | 2019 |
| Inhibition of bacterial gene transcription with an RpoN-based stapled peptide SR Payne, DI Pau, AL Whiting, YJ Kim, BM Pharoah, C Moi, CN Boddy, ... Cell chemical biology 25 (9), 1059-1066. e4, 2018 | 18 | 2018 |
