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Nicola A. Scott
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Cholesterol increases protein levels of the E3 ligase MARCH6 and thereby stimulates protein degradation
LJ Sharpe, V Howe, NA Scott, W Luu, L Phan, JM Berk, M Hochstrasser, ...
Journal of Biological Chemistry 294 (7), 2436-2448, 2019
392019
The cholesterol synthesis enzyme lanosterol 14α-demethylase is post-translationally regulated by the E3 ubiquitin ligase MARCH6
NA Scott, LJ Sharpe, IM Capell-Hattam, SJ Gullo, W Luu, AJ Brown
Biochemical Journal 477 (2), 541-555, 2020
282020
The E3 ubiquitin ligase MARCHF6 as a metabolic integrator in cholesterol synthesis and beyond
NA Scott, LJ Sharpe, AJ Brown
Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2021
222021
Valosin-containing protein mediates the ERAD of squalene monooxygenase and its cholesterol-responsive degron
NK Chua, NA Scott, AJ Brown
Biochemical Journal 476 (18), 2545-2560, 2019
162019
Cholesterol synthesis enzyme SC4MOL is fine-tuned by sterols and targeted for degradation by the E3 ligase MARCHF6
L Qian, NA Scott, IM Capell-Hattam, EA Draper, NM Fenton, W Luu, ...
Journal of Lipid Research 64 (5), 2023
72023
The role of the rhomboid superfamily in ER protein quality control: from mechanisms and functions to diseases
S Bhaduri, NA Scott, SE Neal
Cold Spring Harbor Perspectives in Biology 15 (2), a041248, 2023
22023
SC5D is the sixth enzyme in cholesterol biosynthesis targeted by the E3 ubiquitin ligase MARCHF6.
NM Fenton, L Qian, NA Scott, EG Paine, LJ Sharpe, AJ Brown
Biochimica et Biophysica acta. Molecular and Cell Biology of Lipids, 159482 …, 2024
2024
The Mammalian Rhomboid-like Derlins Regulate Endoplasmic Reticulum Morphology
E Jordahl, N Scott, S Neal
Journal of Biological Chemistry 299 (3), S581, 2023
2023
The E3 ubiquitin ligase MARCHF6 is a critical regulator of cholesterol metabolism
N Scott
UNSW Sydney, 2021
2021
Squalene Monooxygenase at the Nexus between Cholesterol Homeostasis and Proteostasis
NK Chua, V Howe, N Jatana, G Hart-Smith, NA Scott, L Thukral, AJ Brown
The FASEB Journal 34 (S1), 1-1, 2020
2020
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