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David R. J. Palmer
David R. J. Palmer
Department of Chemistry, University of Saskatchewan
Verified email at usask.ca - Homepage
Title
Cited by
Cited by
Year
The enolase superfamily: a general strategy for enzyme-catalyzed abstraction of the α-protons of carboxylic acids
PC Babbitt, MS Hasson, JE Wedekind, DRJ Palmer, WC Barrett, GH Reed, ...
Biochemistry 35 (51), 16489-16501, 1996
4291996
Unexpected divergence of enzyme function and sequence:“N-acylamino acid racemase” is o-succinylbenzoate synthase
DRJ Palmer, JB Garrett, V Sharma, R Meganathan, PC Babbitt, JA Gerlt
Biochemistry 38 (14), 4252-4258, 1999
1631999
Evolution of enzymatic activities in the enolase superfamily: characterization of the (D)-glucarate/galactarate catabolic pathway in Escherichia coli
BK Hubbard, M Koch, DRJ Palmer, PC Babbitt, JA Gerlt
Biochemistry 37 (41), 14369-14375, 1998
1041998
Succinylphosphonate esters are competitive inhibitors of MenD that show active-site discrimination between homologous α-ketoglutarate-decarboxylating enzymes
M Fang, RD Toogood, A Macova, K Ho, SG Franzblau, MR McNeil, ...
Biochemistry 49 (12), 2672-2679, 2010
582010
Evolution of enzymatic activities in the enolase superfamily: crystallographic and mutagenesis studies of the reaction catalyzed by D-glucarate dehydratase from Escherichia coli
AM Gulick, BK Hubbard, JA Gerlt, I Rayment
Biochemistry 39 (16), 4590-4602, 2000
582000
The Lesser “Burden Borne” by o-Succinylbenzoate Synthase:  An “Easy” Reaction Involving a Carboxylate Carbon Acid
EA Taylor, DRJ Palmer, JA Gerlt
Journal of the American Chemical Society 123 (24), 5824-5825, 2001
492001
A Previously Unrecognized Kanosamine Biosynthesis Pathway in Bacillus subtilis
ND Vetter, DM Langill, S Anjum, J Boisvert-Martel, RC Jagdhane, ...
Journal of the American Chemical Society 135 (16), 5970-5973, 2013
462013
Evolution of Enzymatic Activities in the Enolase Superfamily:  Crystal Structure of (D)-Glucarate Dehydratase from Pseudomonas putida,
AM Gulick, DRJ Palmer, PC Babbitt, JA Gerlt, I Rayment
Biochemistry 37 (41), 14358-14368, 1998
461998
Methanogen Homoaconitase Catalyzes Both Hydrolyase Reactions in Coenzyme B Biosynthesis∗
RM Drevland, Y Jia, DRJ Palmer, DE Graham
Journal of biological chemistry 283 (43), 28888-28896, 2008
422008
Steady-State Kinetics and Molecular Evolution of Escherichia coli MenD [(1R,6R)-2-Succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate Synthase], an …
M Bhasin, JL Billinsky, DRJ Palmer
Biochemistry 42 (46), 13496-13504, 2003
402003
Using Substrate Analogues To Probe the Kinetic Mechanism and Active Site of Escherichia coli MenD
M Fang, A Macova, KL Hanson, J Kos, DRJ Palmer
Biochemistry 50 (40), 8712-8721, 2011
322011
Biomimetic Design Results in a Potent Allosteric Inhibitor of Dihydrodipicolinate Synthase from Campylobacter jejuni
YV Skovpen, CJT Conly, DAR Sanders, DRJ Palmer
Journal of the American Chemical Society 138 (6), 2014-2020, 2016
312016
Kinetics and product analysis of the reaction catalysed by recombinant homoaconitase from Thermus thermophilus
Y Jia, T Tomita, K Yamauchi, M Nishiyama, DRJ Palmer
Biochemical Journal 396 (3), 479-485, 2006
302006
The structure of NtdA, a sugar aminotransferase involved in the kanosamine biosynthetic pathway in Bacillus subtilis, reveals a new subclass of aminotransferases
KE van Straaten, JB Ko, R Jagdhane, S Anjum, DRJ Palmer, ...
Journal of Biological Chemistry 288 (47), 34121-34130, 2013
292013
Synthesis and antifungal properties of compounds which target the α-aminoadipate pathway
DRJ Palmer, H Balogh, G Ma, X Zhou, M Marko, SGW Kaminskyj
Die Pharmazie-An International Journal of Pharmaceutical Sciences 59 (2), 93-98, 2004
282004
Evolution of enzymatic activities: multiple pathways for generating and partitioning a common enolic intermediate by glucarate dehydratase from Pseudomonas putida
DRJ Palmer, JA Gerlt
Journal of the American Chemical Society 118 (42), 10323-10324, 1996
281996
Dihydrodipicolinate Synthase from Campylobacter jejuni: Kinetic Mechanism of Cooperative Allosteric Inhibition and Inhibitor-Induced Substrate Cooperativity
YV Skovpen, DRJ Palmer
Biochemistry 52 (32), 5454-5462, 2013
262013
Evolution of enzymatic activities in the enolase superfamily: Partitioning of reactive intermediates by (D)-glucarate dehydratase from Pseudomonas putida
DRJ Palmer, BK Hubbard, JA Gerlt
Biochemistry 37 (41), 14350-14357, 1998
251998
Evidence of allosteric enzyme regulation via changes in conformational dynamics: a hydrogen/deuterium exchange investigation of dihydrodipicolinate synthase
MA Sowole, S Simpson, YV Skovpen, DRJ Palmer, L Konermann
Biochemistry 55 (38), 5413-5422, 2016
242016
Kinetic evaluation of glucose 1-phosphate analogues with a thymidylyltransferase using a continuous coupled enzyme assay
SM Forget, A Jee, DA Smithen, R Jagdhane, S Anjum, SA Beaton, ...
Organic & Biomolecular Chemistry 13 (3), 866-875, 2015
242015
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