Craig Morton
Craig Morton
Principal Research Scientist, CSIRO
Verified email at
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Mechanism of activation of protein kinase JAK2 by the growth hormone receptor
AJ Brooks, W Dai, ML O’Mara, D Abankwa, Y Chhabra, RA Pelekanos, ...
Science 344 (6185), 1249783, 2014
Solution structure of the link module: a hyaluronan-binding domain involved in extracellular matrix stability and cell migration
D Kohda, CJ Morton, AA Parkar, H Hatanaka, FM Inagaki, ID Campbell, ...
Cell 86 (5), 767-775, 1996
Structure of the Alzheimer's disease amyloid precursor protein copper binding domain: a regulator of neuronal copper homeostasis
KJ Barnham, WJ McKinstry, G Multhaup, D Galatis, CJ Morton, CC Curtain, ...
Journal of Biological Chemistry 278 (19), 17401-17407, 2003
Oncogenic protein interfaces: small molecules, big challenges
TL Nero, CJ Morton, JK Holien, J Wielens, MW Parker
Nature Reviews Cancer 14 (4), 248-262, 2014
Anxiety over GABAA receptor structure relieved by AChBP
BA Cromer, CJ Morton, MW Parker
Trends in biochemical sciences 27 (6), 280-287, 2002
Intrasteric control of AMPK via the γ1 subunit AMP allosteric regulatory site
J Adams, ZP Chen, BJW Van Denderen, CJ Morton, MW Parker, ...
Protein science 13 (1), 155-165, 2004
The folding kinetics and thermodynamics of the Fyn-SH3 domain
KW Plaxco, JI Guijarro, CJ Morton, M Pitkeathly, ID Campbell, CM Dobson
Biochemistry 37 (8), 2529-2537, 1998
Rational design of an organometallic glutathione transferase inhibitor
WH Ang, LJ Parker, A De Luca, L Juillerat‐Jeanneret, CJ Morton, ...
Angewandte Chemie International Edition 48 (21), 3854-3857, 2009
Critical role for the second extracellular loop in the binding of both orthosteric and allosteric G protein-coupled receptor ligands
VA Avlani, KJ Gregory, CJ Morton, MW Parker, PM Sexton, ...
Journal of Biological Chemistry 282 (35), 25677-25686, 2007
Transitional changes in the CRP structure lead to the exposure of proinflammatory binding sites
D Braig, TL Nero, HG Koch, B Kaiser, X Wang, JR Thiele, CJ Morton, ...
Nature communications 8 (1), 14188, 2017
Folding kinetics of the SH3 domain of PI3 kinase by real-time NMR combined with optical spectroscopy
JI Guijarro, CJ Morton, KW Plaxco, ID Campbell, CM Dobson
Journal of molecular biology 276 (3), 657-667, 1998
Cytoplasmic ATP-sensing domains regulate gating of skeletal muscle ClC-1 chloride channels
B Bennetts, GY Rychkov, HL Ng, CJ Morton, D Stapleton, MW Parker, ...
Journal of Biological Chemistry 280 (37), 32452-32458, 2005
Water mediated protein‐DNA interactions: The relationship of thermodynamics to structural detail
CJ Morton, JE Ladbury
Protein Science 5 (10), 2115-2118, 1996
Solution structure and peptide binding of the SH3 domain from human Fyn
CJ Morton, DJR Pugh, ELJ Brown, JD Kahmann, DAC Renzoni, ...
Structure 4 (6), 705-714, 1996
SH3 Domains: Molecular ‘Velcro’1
CJ Morton, ID Campbell
Current Biology 4 (7), 615-617, 1994
Potent hepatitis C inhibitors bind directly to NS5A and reduce its affinity for RNA
DB Ascher, J Wielens, TL Nero, L Doughty, CJ Morton, MW Parker
Scientific reports 4 (1), 4765, 2014
Structural and thermodynamic characterization of the interaction of the SH3 domain from Fyn with the proline-rich binding site on the p85 subunit of PI3-kinase
DA Renzoni, DJR Pugh, G Siligardi, P Das, CJ Morton, C Rossi, ...
Biochemistry 35 (49), 15646-15653, 1996
The effects of guanidine hydrochloride on the’random coil ‘conformations and NMR chemical shifts of the peptide series GGXGG
KW Plaxco, CJ Morton, SB Grimshaw, JA Jones, M Pitkeathly, ...
Journal of biomolecular NMR 10, 221-230, 1997
Identification and characterization of a new cognitive enhancer based on inhibition of insulin‐regulated aminopeptidase
AL Albiston, CJ Morton, HL Ng, V Pham, HR Yeatman, S Ye, ...
The FASEB Journal 22 (12), 4209-4217, 2008
Molecular Evolution of Glutathione S-Transferases in the Genus Drosophila
WY Low, HL Ng, CJ Morton, MW Parker, P Batterham, C Robin
Genetics 177 (3), 1363-1375, 2007
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