Johannes Zuber
Johannes Zuber
Group Leader - IMP (Research Institute of Molecular Pathology), Vienna, Austria
Verified email at - Homepage
TitleCited byYear
RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia
J Zuber, J Shi, E Wang, AR Rappaport, H Herrmann, EA Sison, D Magoon, ...
Nature 478 (7370), 524, 2011
Cancer stem cell definitions and terminology: the devil is in the details
P Valent, D Bonnet, R De Maria, T Lapidot, M Copland, JV Melo, ...
Nature Reviews Cancer 12 (11), 767, 2012
An oncogenomics-based in vivo RNAi screen identifies tumor suppressors in liver cancer
L Zender, W Xue, J Zuber, CP Semighini, A Krasnitz, B Ma, P Zender, ...
Cell 135 (5), 852-864, 2008
Toward understanding and exploiting tumor heterogeneity
AA Alizadeh, V Aranda, A Bardelli, C Blanpain, C Bock, C Borowski, ...
Nature medicine 21 (8), 846, 2015
Genome-wide RNA-mediated interference screen identifies miR-19 targets in Notch-induced T-cell acute lymphoblastic leukaemia
KJ Mavrakis, AL Wolfe, E Oricchio, T Palomero, K De Keersmaecker, ...
Nature cell biology 12 (4), 372, 2010
A genome-wide survey of RAS transformation targets
J Zuber, OI Tchernitsa, B Hinzmann, AC Schmitz, M Grips, M Hellriegel, ...
Nature genetics 24 (2), 144, 2000
An optimized microRNA backbone for effective single-copy RNAi
C Fellmann, T Hoffmann, V Sridhar, B Hopfgartner, M Muhar, M Roth, ...
Cell reports 5 (6), 1704-1713, 2013
Anti-apoptotic Mcl-1 is essential for the development and sustained growth of acute myeloid leukemia
SP Glaser, EF Lee, E Trounson, P Bouillet, A Wei, WD Fairlie, DJ Izon, ...
Genes & development 26 (2), 120-125, 2012
A rapid and scalable system for studying gene function in mice using conditional RNA interference
PK Premsrirut, LE Dow, SY Kim, M Camiolo, CD Malone, C Miething, ...
Cell 145 (1), 145-158, 2011
Transcriptional plasticity promotes primary and acquired resistance to BET inhibition
P Rathert, M Roth, T Neumann, F Muerdter, JS Roe, M Muhar, S Deswal, ...
Nature 525 (7570), 543, 2015
TAp63 induces senescence and suppresses tumorigenesis in vivo
X Guo, WM Keyes, C Papazoglu, J Zuber, W Li, SW Lowe, H Vogel, ...
Nature cell biology 11 (12), 1451, 2009
Role of SWI/SNF in acute leukemia maintenance and enhancer-mediated Myc regulation
J Shi, WA Whyte, CJ Zepeda-Mendoza, JP Milazzo, C Shen, JS Roe, ...
Genes & development 27 (24), 2648-2662, 2013
Toolkit for evaluating genes required for proliferation and survival using tetracycline-regulated RNAi
J Zuber, K McJunkin, C Fellmann, LE Dow, MJ Taylor, GJ Hannon, ...
Nature biotechnology 29 (1), 79, 2011
Forward and reverse genetics through derivation of haploid mouse embryonic stem cells
U Elling, J Taubenschmid, G Wirnsberger, R O'Malley, SP Demers, ...
Cell stem cell 9 (6), 563-574, 2011
An integrated approach to dissecting oncogene addiction implicates a Myb-coordinated self-renewal program as essential for leukemia maintenance
J Zuber, AR Rappaport, W Luo, E Wang, C Chen, AV Vaseva, J Shi, ...
Genes & development 25 (15), 1628-1640, 2011
Mouse models of human AML accurately predict chemotherapy response
J Zuber, I Radtke, TS Pardee, Z Zhao, AR Rappaport, W Luo, ...
Genes & development 23 (7), 877-889, 2009
Functional identification of optimized RNAi triggers using a massively parallel sensor assay
C Fellmann, J Zuber, K McJunkin, K Chang, CD Malone, RA Dickins, Q Xu, ...
Molecular cell 41 (6), 733-746, 2011
MLL3 is a haploinsufficient 7q tumor suppressor in acute myeloid leukemia
C Chen, Y Liu, AR Rappaport, T Kitzing, N Schultz, Z Zhao, AS Shroff, ...
Cancer cell 25 (5), 652-665, 2014
Functional identification of tumor-suppressor genes through an in vivo RNA interference screen in a mouse lymphoma model
A Bric, C Miething, CU Bialucha, C Scuoppo, L Zender, A Krasnitz, Z Xuan, ...
Cancer cell 16 (4), 324-335, 2009
In vivo RNAi screening identifies a mechanism of sorafenib resistance in liver cancer
R Rudalska, D Dauch, T Longerich, K McJunkin, T Wuestefeld, TW Kang, ...
Nature medicine 20 (10), 1138, 2014
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