Natalie Trevaskis
Natalie Trevaskis
Associate Professor, Monash University
Verified email at
Cited by
Cited by
Lipids and lipid-based formulations: optimizing the oral delivery of lipophilic drugs
CJH Porter, NL Trevaskis, WN Charman
Nature reviews Drug discovery 6 (3), 231-248, 2007
Strategies to address low drug solubility in discovery and development
HD Williams, NL Trevaskis, SA Charman, RM Shanker, WN Charman, ...
Pharmacological reviews 65 (1), 315-499, 2013
From sewer to saviour—targeting the lymphatic system to promote drug exposure and activity
NL Trevaskis, LM Kaminskas, CJH Porter
Nature reviews Drug discovery 14 (11), 781-803, 2015
Lipid-based delivery systems and intestinal lymphatic drug transport: a mechanistic update
NL Trevaskis, WN Charman, CJH Porter
Advanced drug delivery reviews 60 (6), 702-716, 2008
50 years of oral lipid-based formulations: provenance, progress and future perspectives
OM Feeney, MF Crum, CL McEvoy, NL Trevaskis, HD Williams, ...
Advanced drug delivery reviews 101, 167-194, 2016
The mechanisms of pharmacokinetic food-drug interactions–A perspective from the UNGAP group
M Koziolek, S Alcaro, P Augustijns, AW Basit, M Grimm, B Hens, CL Hoad, ...
European Journal of Pharmaceutical Sciences 134, 31-59, 2019
Impact of gastrointestinal tract variability on oral drug absorption and pharmacokinetics: An UNGAP review
Z Vinarov, M Abdallah, JAG Agundez, K Allegaert, AW Basit, ...
European Journal of Pharmaceutical Sciences 162, 105812, 2021
Sex-specific adipose tissue imprinting of regulatory T cells
A Vasanthakumar, D Chisanga, J Blume, R Gloury, K Britt, DC Henstridge, ...
Nature 579 (7800), 581-585, 2020
From influenza to COVID-19: Lipid nanoparticle mRNA vaccines at the frontiers of infectious diseases
EH Pilkington, EJA Suys, NL Trevaskis, AK Wheatley, D Zukancic, ...
Acta biomaterialia 131, 16-40, 2021
Lipid-based formulations and drug supersaturation: harnessing the unique benefits of the lipid digestion/absorption pathway
HD Williams, NL Trevaskis, YY Yeap, MU Anby, CW Pouton, CJH Porter
Pharmaceutical research 30, 2976-2992, 2013
Targeted delivery of a model immunomodulator to the lymphatic system: comparison of alkyl ester versus triglyceride mimetic lipid prodrug strategies
S Han, T Quach, L Hu, A Wahab, WN Charman, VJ Stella, NL Trevaskis, ...
Journal of Controlled Release 177, 1-10, 2014
Intestinal bile secretion promotes drug absorption from lipid colloidal phases via induction of supersaturation
YY Yeap, NL Trevaskis, T Quach, P Tso, WN Charman, CJH Porter
Molecular pharmaceutics 10 (5), 1874-1889, 2013
A new in vitro lipid digestion – in vivo absorption model to evaluate the mechanisms of drug absorption from lipid-based formulations
MF Crum, NL Trevaskis, HD Williams, CW Pouton, CJH Porter
Pharmaceutical research 33, 970-982, 2016
Targeted drug delivery to lymphocytes: a route to site-specific immunomodulation?
NL Trevaskis, WN Charman, CJH Porter
Molecular pharmaceutics 7 (6), 2297-2309, 2010
Lipid absorption triggers drug supersaturation at the intestinal unstirred water layer and promotes drug absorption from mixed micelles
YY Yeap, NL Trevaskis, CJH Porter
Pharmaceutical research 30, 3045-3058, 2013
Methotrexate-conjugated PEGylated dendrimers show differential patterns of deposition and activity in tumor-burdened lymph nodes after intravenous and subcutaneous …
LM Kaminskas, VM McLeod, DB Ascher, GM Ryan, S Jones, JM Haynes, ...
Molecular pharmaceutics 12 (2), 432-443, 2015
The lymph lipid precursor pool is a key determinant of intestinal lymphatic drug transport
NL Trevaskis, CJH Porter, WN Charman
Journal of Pharmacology and Experimental Therapeutics 316 (2), 881-891, 2006
Lymphatic targeting by albumin-hitchhiking: applications and optimisation
M Abdallah, OO Müllertz, IK Styles, A Mörsdorf, JF Quinn, MR Whittaker, ...
Journal of Controlled Release 327, 117-128, 2020
Glyceride‐mimetic prodrugs incorporating self‐immolative spacers promote lymphatic transport, avoid first‐pass metabolism, and enhance oral bioavailability
L Hu, T Quach, S Han, SF Lim, P Yadav, D Senyschyn, NL Trevaskis, ...
Angewandte Chemie 128 (44), 13904-13909, 2016
Mesenteric lymphatic dysfunction promotes insulin resistance and represents a potential treatment target in obesity
E Cao, MJ Watt, CJ Nowell, T Quach, JS Simpson, V De Melo Ferreira, ...
Nature metabolism 3 (9), 1175-1188, 2021
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