| Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes SL Masters, A Dunne, SL Subramanian, RL Hull, GM Tannahill, FA Sharp, ... Nature immunology 11 (10), 897-904, 2010 | 1424 | 2010 |
| Intestinal FXR agonism promotes adipose tissue browning and reduces obesity and insulin resistance S Fang, JM Suh, SM Reilly, E Yu, O Osborn, D Lackey, E Yoshihara, ... Nature medicine 21 (2), 159-165, 2015 | 733 | 2015 |
| Thioredoxin/Txnip: redoxisome, as a redox switch for the pathogenesis of diseases E Yoshihara, S Masaki, Y Matsuo, Z Chen, H Tian, J Yodoi Frontiers in immunology 4, 76697, 2014 | 356 | 2014 |
| FXR regulates intestinal cancer stem cell proliferation T Fu, S Coulter, E Yoshihara, TG Oh, S Fang, F Cayabyab, Q Zhu, ... Cell 176 (5), 1098-1112. e18, 2019 | 340 | 2019 |
| Endocrinization of FGF1 produces a neomorphic and potent insulin sensitizer JM Suh, JW Jonker, M Ahmadian, R Goetz, D Lackey, O Osborn, Z Huang, ... Nature 513 (7518), 436-439, 2014 | 265 | 2014 |
| Immune-evasive human islet-like organoids ameliorate diabetes E Yoshihara, C O’Connor, E Gasser, Z Wei, TG Oh, TW Tseng, D Wang, ... Nature 586 (7830), 606-611, 2020 | 241 | 2020 |
| Vitamin D switches BAF complexes to protect β cells Z Wei, E Yoshihara, N He, N Hah, W Fan, AFM Pinto, T Huddy, Y Wang, ... Cell 173 (5), 1135-1149. e15, 2018 | 204 | 2018 |
| ERRγ is required for the metabolic maturation of therapeutically functional glucose-responsive β cells E Yoshihara, Z Wei, CS Lin, S Fang, M Ahmadian, Y Kida, T Tseng, Y Dai, ... Cell metabolism 23 (4), 622-634, 2016 | 175 | 2016 |
| ERRs mediate a metabolic switch required for somatic cell reprogramming to pluripotency YS Kida, T Kawamura, Z Wei, T Sogo, S Jacinto, A Shigeno, H Kushige, ... Cell stem cell 16 (5), 547-555, 2015 | 142 | 2015 |
| Disruption of TBP-2 ameliorates insulin sensitivity and secretion without affecting obesity E Yoshihara, S Fujimoto, N Inagaki, K Okawa, S Masaki, J Yodoi, ... Nature communications 1 (1), 127, 2010 | 140 | 2010 |
| Thioredoxin binding protein-2/thioredoxin-interacting protein is a critical regulator of insulin secretion and peroxisome proliferator-activated receptor function S Oka*, E Yoshihara* (*co-first author), A Bizen-Abe, W Liu, M Watanabe, ... Endocrinology 150 (3), 1225-1234, 2008 | 104 | 2008 |
| Thioredoxin binding protein (TBP)-2/Txnip and α-arrestin proteins in cancer and diabetes mellitus H Masutani, E Yoshihara, S Masaki, Z Chen, J Yodoi Journal of clinical biochemistry and nutrition 50 (1), 23-34, 2011 | 75 | 2011 |
| TXNIP/TBP-2: a master regulator for glucose homeostasis E Yoshihara Antioxidants 9 (8), 765, 2020 | 74 | 2020 |
| Thiol redox transitions by thioredoxin and thioredoxin-binding protein-2 in cell signaling E Yoshihara, Z Chen, Y Matsuo, H Masutani, J Yodoi Methods in enzymology 474, 67-82, 2010 | 67 | 2010 |
| Advances in pancreatic islet transplantation sites for the treatment of diabetes F Cayabyab, LR Nih, E Yoshihara Frontiers in Endocrinology 12, 732431, 2021 | 57 | 2021 |
| Deficiency of thioredoxin binding protein-2 (TBP-2) enhances TGF-β signaling and promotes epithelial to mesenchymal transition S Masaki, H Masutani, E Yoshihara, J Yodoi PLoS One 7 (6), e39900, 2012 | 40 | 2012 |
| Dendritic cells derived from TBP‐2‐deficient mice are defective in inducing T cell responses A Son, H Nakamura, H Okuyama, S Oka, E Yoshihara, W Liu, Y Matsuo, ... European journal of immunology 38 (5), 1358-1367, 2008 | 37 | 2008 |
| ERRγ preserves brown fat innate thermogenic activity M Ahmadian, S Liu, SM Reilly, N Hah, W Fan, E Yoshihara, P Jha, ... Cell reports 22 (11), 2849-2859, 2018 | 31 | 2018 |
| Thioredoxin-binding protein-2 (TBP-2/VDUP1/TXNIP) regulates T-cell sensitivity to glucocorticoid during HTLV-I-induced transformation Z Chen, DA Lopez-Ramos, E Yoshihara, Y Maeda, H Masutani, K Sugie, ... Leukemia 25 (3), 440-448, 2011 | 31 | 2011 |
| Differential roles of Annexin A1 (ANXA1/lipocortin-1/lipomodulin) and thioredoxin binding protein-2 (TBP-2/VDUP1/TXNIP) in glucocorticoid signaling of HTLV-I-transformed T cells Z Chen, E Yoshihara, A Son, Y Matsuo, H Masutani, K Sugie, M Maeda, ... Immunology letters 131 (1), 11-18, 2010 | 31 | 2010 |
